Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jenifer E. Shattuck"'
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The factors regulating stress granule dissolution are not fully understood. Here, the authors identify Sky1 as a stress granule component in yeast, and show that Sky1 kinase activity is required for timely stress granule disassembly during stress rec
Externí odkaz:
https://doaj.org/article/a7152e5c571747a8a63d8a8f489ddb47
Autor:
Eric D. Ross, Andrew K. Lamb, Matthew H. Baer, Kacy R. Paul, Jenifer E. Shattuck, Sean M. Cascarina, Amy E. Boncella, Anastasia Fomicheva
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Many RNA-binding proteins contain aggregation-prone prion-like domains (PrLDs), and mutations in several of these have been linked to degenerative diseases. Additionally, many of these proteins are associated with stress granules, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da2d328bf01f6d94e1ea05875b7670c4
https://doi.org/10.1073/pnas.1912723117
https://doi.org/10.1073/pnas.1912723117
Publikováno v:
Curr Genet
Serine‐arginine (SR) protein kinases regulate diverse cellular activities, including various steps in RNA maturation and transport. The yeast Saccharomyces cerevisiae expresses a single SR kinase, Sky1. Sky1 has a bipartite kinase domain, separated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6157c4ffca65e02a8dc48b58501e618
https://doi.org/10.1007/s00294-019-01044-z
https://doi.org/10.1007/s00294-019-01044-z
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Nature Communications
Stress granules are membraneless protein- and mRNA-rich organelles that form in response to perturbations in environmental conditions. Stress granule formation is reversible, and persistent stress granules have been implicated in a variety of neurode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad86724b2d3dae1fd22e37202817162d
https://doaj.org/article/a7152e5c571747a8a63d8a8f489ddb47
https://doaj.org/article/a7152e5c571747a8a63d8a8f489ddb47
Autor:
Margaret Gruca, Aubrey Waechter, Kyle S. MacLea, Jenifer E. Shattuck, Eric D. Ross, Zobaida Ben-Musa, Kacy R. Paul
Publikováno v:
Molecular and cellular biology. 35(5)
Multiple yeast prions have been identified that result from the structural conversion of proteins into a self-propagating amyloid form. Amyloid-based prion activity in yeast requires a series of discrete steps. First, the prion protein must form an a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9439d71c41ff27a64f7d9043f569d0d4
https://pubmed.ncbi.nlm.nih.gov/25547291
https://pubmed.ncbi.nlm.nih.gov/25547291
Autor:
Melissa B. Coates, Brett D. Blakeley, Ite A. Laird-Offringa, Evelyn Tran, Jenifer E. Shattuck, Brian R. McNaughton
Publikováno v:
Biochemistry. 52(28)
U1A binds U1hpII, a hairpin RNA with a 10-nucleotide loop. A U1A mutant (ΔK50ΔM51) binds U1hpII-derived hairpins with shorter loops, making it an interesting scaffold for engineering or evolving proteins that bind similarly sized disease-related ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::739d8335cd90f13f27ee76badcc457ad
https://pubmed.ncbi.nlm.nih.gov/23806102
https://pubmed.ncbi.nlm.nih.gov/23806102