Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Jenifer Coburn"'
Autor:
Matthew C. Surdel, Jenifer Coburn
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Leptospirosis is a significant zoonosis worldwide, with disease severity ranging from a mild non-specific illness to multi-organ dysfunction and hemorrhage. The disease is caused by pathogenic bacteria of the genus Leptospira, which are classified in
Externí odkaz:
https://doaj.org/article/dc685a17f50f4bf4bf56e61fb04f8967
Autor:
Michael W. Curtis, Christa H. Fierros, Beth L. Hahn, Matthew C. Surdel, Julie Kessler, Phillip N. Anderson, Marine Vandewalle-Capo, Mari Bonde, Jieqing Zhu, Sven Bergström, Jenifer Coburn
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
P66, a bifunctional integral outer membrane protein, is necessary for Borrelia burgdorferi to establish initial infection and to disseminate in mice. The integrin binding function of P66 facilitates extravasation and dissemination, but the role of it
Externí odkaz:
https://doaj.org/article/b6ebf64375444d37a26cc3a9e0849ecc
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Leptospirosis is an important cause of morbidity and mortality worldwide. Disease severity ranges from asymptomatic colonization to widespread hemorrhage and multiorgan dysfunction. The causative agents, Leptospira spp., are zoonotic Gram-negative sp
Externí odkaz:
https://doaj.org/article/07560083817d440fb765b2226fee1076
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Leptospirosis is an emerging zoonosis caused by pathogenic Leptospira spp. Because rodents are natural hosts of Leptospira, rodent models of pathogenesis have been limited, but are valuable to understand infection in reservoir animals even in the abs
Externí odkaz:
https://doaj.org/article/79bdb5ba13d64961bff1028a35dbfa0f
Autor:
Xi Tan, Yi-Pin Lin, Michael J Pereira, Mildred Castellanos, Beth L Hahn, Phillip Anderson, Jenifer Coburn, John M Leong, George Chaconas
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010511 (2022)
Hematogenous dissemination is a critical step in the evolution of local infection to systemic disease. The Lyme disease (LD) spirochete, which efficiently disseminates to multiple tissues, has provided a model for this process, in particular for the
Externí odkaz:
https://doaj.org/article/7b7e2ab6362140cd9904abec60836d9d
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/f3f4b575062a4fa8af6948a5fd58deb2
Autor:
Yi-Pin Lin, Xi Tan, Jennifer A Caine, Mildred Castellanos, George Chaconas, Jenifer Coburn, John M Leong
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008516 (2020)
Lyme disease, caused by Borrelia burgdorferi, B. afzelii and B. garinii, is a chronic, multi-systemic infection and the spectrum of tissues affected can vary with the Lyme disease strain. For example, whereas B. garinii infection is associated with n
Externí odkaz:
https://doaj.org/article/1ad014698e9545f688fb88e77871c272
Autor:
Christa Winslow, Jenifer Coburn
Publikováno v:
F1000Research, Vol 8 (2019)
This review highlights some of the highest-profile developments and advancements in the research on Borrelia burgdorferi, the Lyme disease spirochete, that have emerged in the last two years. Particular emphasis is placed on the controversy surroundi
Externí odkaz:
https://doaj.org/article/5be81f6217e3436aa08de32d98230b2f
Autor:
Hiromi Sato, Jenifer Coburn
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 7, p e0005830 (2017)
Pathogenic Leptospira transmits from animals to humans, causing the zoonotic life-threatening infection called leptospirosis. This infection is reported worldwide with higher risk in tropical regions. Symptoms of leptospirosis range from mild illness
Externí odkaz:
https://doaj.org/article/27e28ddeb52e45c98cc7401ec7294955
Autor:
Jennifer A Caine, Jenifer Coburn
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Borrelia burgdorferi is the causative agent of Lyme disease in the U.S., with at least 25,000 cases reported to the CDC each year. B. burgdorferi is thought to enter and exit the bloodstream to achieve rapid dissemination to distal tissue sites durin
Externí odkaz:
https://doaj.org/article/c177e4ae215e46b29ef13c6e676ab928