Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jeni C. Luckett"'
Autor:
Alison E. John, Rebecca H. Graves, K. Tao Pun, Giovanni Vitulli, Ellen J. Forty, Paul F. Mercer, Josie L. Morrell, John W. Barrett, Rebecca F. Rogers, Maryam Hafeji, Lloyd I. Bibby, Elaine Gower, Valerie S. Morrison, Yim Man, James A. Roper, Jeni C. Luckett, Lee A. Borthwick, Ben S. Barksby, Rachel A. Burgoyne, Rory Barnes, Joelle Le, David J. Flint, Susan Pyne, Anthony Habgood, Louise A. Organ, Chitra Joseph, Rochelle C. Edwards-Pritchard, Toby M. Maher, Andrew J. Fisher, Natasja Stæhr Gudmann, Diana J. Leeming, Rachel C. Chambers, Pauline T. Lukey, Richard P. Marshall, Simon J. F. Macdonald, R. Gisli Jenkins, Robert J. Slack
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The αvβ6 integrin is key in activating the pro-fibrotic cytokine TGFβ in idiopathic pulmonary fibrosis. Here, the authors show an inhaled small molecule αvβ6 inhibitor GSK3008348 induces prolonged inhibition of TGFβ signaling pathways in human
Externí odkaz:
https://doaj.org/article/0b6e5916f4cb4d2e9b4186f07f1b86ee
Autor:
Jo E. Lewis, Ricardo J. Samms, Scott Cooper, Jeni C. Luckett, Alan C. Perkins, Andrew C. Adams, Kostas Tsintzas, Francis J. P. Ebling
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract FGF21 exerts profound metabolic effects in Siberian hamsters exposed to long day (LD) photoperiods that increase appetite and adiposity, however these effects are attenuated in short day (SD) animals that display hypophagia and reduced adipo
Externí odkaz:
https://doaj.org/article/95e972ce73d34b99befdbcf40d02600f
Autor:
Cansu Karyal, Jaime Hughes, Michelle L. Kelly, Jeni C. Luckett, Philip V. Kaye, Alan Cockayne, Nigel P. Minton, Ruth Griffin
Publikováno v:
Microorganisms, Vol 9, Iss 2, p 306 (2021)
Clostridioides difficile is the main cause of health-care-associated infectious diarrhoea. Toxins, TcdA and TcdB, secreted by this bacterium damage colonic epithelial cells and in severe cases this culminates in pseudomembranous colitis, toxic megaco
Externí odkaz:
https://doaj.org/article/e611c52d6d454bf3b11ceedab05891c6
Autor:
Waraporn Suvannapruk, Leanne E Fisher, Jeni C Luckett, Max K Edney, Anna M Kotowska, Dong‐Hyun Kim, David J Scurr, Amir M Ghaemmaghami, Morgan R Alexander
Publikováno v:
Advanced Science, Vol 11, Iss 15, Pp n/a-n/a (2024)
Abstract A key goal for implanted medical devices is that they do not elicit a detrimental immune response. Macrophages play critical roles in the modulation of the host immune response and are the cells responsible for persistent inflammatory reacti
Externí odkaz:
https://doaj.org/article/b5cf615ac2274b8cbf84de8de62bd4aa
Autor:
Jean-Frédéric Dubern, Andrew L. Hook, Alessandro M. Carabelli, Chien-Yi Chang, Christopher A. Lewis-Lloyd, Jeni C. Luckett, Laurence Burroughs, Adam A. Dundas, David J. Humes, Derek J. Irvine, Morgan R. Alexander, Paul Williams
Publikováno v:
Science Advances. 9
Innovative approaches to prevent catheter-associated urinary tract infections (CAUTIs) are urgently required. Here, we describe the discovery of an acrylate copolymer capable of resisting single- and multispecies bacterial biofilm formation, swarming