Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jeng-dar Yang"'
Autor:
Chenfei Huang, Yuechao Zhao, Shengchen Lin, Lin Li, Xuan Guo, Sebastian Yumiseba, Jeng-dar Yang, Robert Hariri, Qian Ye, Shuyang He, Adrian Kilcoyne
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-12 (2023)
Abstract Objective Human placenta-derived exosomes (pExo) were generated, characterized, and evaluated as a therapeutic candidate for the treatment of osteoarthritis (OA). Methods pExo was generated from full-term human placenta tissues by sequential
Externí odkaz:
https://doaj.org/article/eb8bbde944544bb08846f4141663cdb5
Publikováno v:
BioProcessing Journal. 5:15-23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd0b0f18c023f9904306bf6b36f2f743
https://doi.org/10.12665/j53.yang
https://doi.org/10.12665/j53.yang
Autor:
Alaric Collins, Jeng-Dar Yang, Melvin Silberklang, Stephen Czarnecki, Hong-Hue Hsu, Peter Gecik, Abraham Lasdun, Ganapathy Muthukumar, Ramakrishnan Sundaram
Publikováno v:
Biotechnology and Bioengineering. 52:696-706
We have developed a serum-free cell culture process utilizing a recombinant baculovirus (AcNPV) expression vector to infect Trichoplusia ni insect cells for the production of the human lysosomal enzyme, glucocerebrosidase. The enzyme, which is harves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb13791c6dbdc4a6608b02f57aee832
https://doi.org/10.1002/(sici)1097-0290(19961220)52:6<696::aid-bit7>3.0.co
https://doi.org/10.1002/(sici)1097-0290(19961220)52:6<696::aid-bit7>3.0.co
Publikováno v:
Journal of Biotechnology. 33:107-122
A modeling framework is proposed to assess the detrimental effects of air sparging and other bubble phenomena (vortex entrainment, coalescence, bursting) on freely suspended cells in an aerated, agitated bioreactor. It is assumed that cells may be re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145e0328172518d5aa827b0e34bfa845
https://doi.org/10.1016/0168-1656(94)90104-x
https://doi.org/10.1016/0168-1656(94)90104-x
This paper presents a T-flask based screening platform for evaluating and identifying plant hydrolysates for cell culture processes. The development of this platform was driven by an urgent need of replacing a soy hydrolysate that was no longer avail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5535f7766d103dcba1a6ef0c7c24482c
https://europepmc.org/articles/PMC2289789/
https://europepmc.org/articles/PMC2289789/
Autor:
Michael Benjamino, Canghai Lu, Carlos Gonzalez, Brad Stasny, Jennifer Gangi, Brett Collopy, Melissa Hanson, Joseph Gleason, Woodrow Guinto, Monica Fung, Joseph Henley, Jeng-Dar Yang, Elisabeth Ille
Publikováno v:
Biotechnology and bioengineering. 98(1)
This case study focuses on the scale-up of a Sp2/0 mouse myeloma cell line based fed-batch bioreactor process, from the initial 3-L bench scale to the 2,500-L scale. A stepwise scale-up strategy that involved several intermediate steps in increasing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d233e663d8fb2a4d72dae7709e63b1a
https://pubmed.ncbi.nlm.nih.gov/17657776
https://pubmed.ncbi.nlm.nih.gov/17657776
Publikováno v:
Biotechnology and bioengineering. 69(1)
Controlled feeding of nutrient supplements to a cell culture to enhance monoclonal antibody productivity has been practiced widely in high-yield, fed-batch processes. In this study, a similar feeding concept has been applied to a perfused culture and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9876c8f1b602011a34eefcaaccb6edd
https://pubmed.ncbi.nlm.nih.gov/10820333
https://pubmed.ncbi.nlm.nih.gov/10820333
Autor:
Maoliang Wang, Marc Whitlow, L. S. Lee, A. Nepomich, Jeng-Dar Yang, Charles D. Conover, David Filpula
Publikováno v:
Protein engineering. 11(12)
Unlike natural antibodies, single-chain Fv (sFv) proteins normally lack asparagine-linked glycosylation. Many designed immunoconjugates and other therapeutics currently employ the advantageous conjugation chemistry or targeting properties provided by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fecc199f26dd9875eda664989d83d7f5
https://pubmed.ncbi.nlm.nih.gov/9930678
https://pubmed.ncbi.nlm.nih.gov/9930678
Autor:
Nam Sun Wang, Jeng-Dar Yang
Publikováno v:
Applied biochemistry and biotechnology. 42(1)
An in situ optical probe was developed to measure reliably the local specific interfacial area of the suspended phase (specifically air bubbles) in a bioreactor. The light transmission-based probe can be simply and inexpensively constructed from read
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e69d990a5e64b477afdb651995b3a13
https://pubmed.ncbi.nlm.nih.gov/8215348
https://pubmed.ncbi.nlm.nih.gov/8215348
Autor:
Nam Sun Wang, Jeng-Dar Yang
Publikováno v:
Biotechnology Techniques. 5
A simple, inexpensive apparatus wholly consisting of readily available components is developed to measure the local volumetric gas holdup in aerated agitated bioreactors based on the principle of phase separation. The device can determine the gas hol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f4930a1f413a1568a907fb279cf2c09
https://doi.org/10.1007/bf00185012
https://doi.org/10.1007/bf00185012