Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Jeng-Hsien Yen"'
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 5, Pp 489-498 (2024)
Abstract Large cohort studies have disclosed the association between obesity and rheumatoid arthritis (RA) risk. The sarcopenia prevalence in RA patients can be up to 31%. However, there is little information linking adipokines to sarcopenia in RA, s
Externí odkaz:
https://doaj.org/article/1127807041ad4400b617ccbdd7d7cda1
Autor:
Tzu-Jung Fang, Chia-Hui Lin, Yuan-Zhao Lin, Min-HSi Chiu, Ruei-Nian Li, Hua-Chen Chan, Yao-Tsung Yeh, Jeng-Hsien Yen
Publikováno v:
Journal of the Formosan Medical Association, Vol 121, Iss 8, Pp 1431-1441 (2022)
Background/purpose: Recent studies showed that Histone deacetylases 6 (HDAC6) inhibitors could improve arthritis in rheumatoid arthritis (RA) rodent models, whereas lower HDAC6 expression was observed in RA patients’ synovial fibroblasts, raising t
Externí odkaz:
https://doaj.org/article/0e6c1ea7c4934211be745c8e88414d08
Autor:
Chia-Chun Tseng, Ya-Wen Sung, Kuan-Yu Chen, Pin-Yi Wang, Chang-Yi Yen, Wan-Yu Sung, Cheng-Chin Wu, Tsan-Teng Ou, Wen-Chan Tsai, Wei-Ting Liao, Chung-Jen Chen, Su-Chen Lee, Shun-Jen Chang, Jeng-Hsien Yen
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 11995 (2023)
Connective tissue disease-associated interstitial lung disease (CTD-ILD) is a severe manifestation of CTD that leads to significant morbidity and mortality. Clinically, ILD can occur in diverse CTDs. Pathologically, CTD-ILD is characterized by variou
Externí odkaz:
https://doaj.org/article/521a1d59faac4ac190111c4fb0c46887
Autor:
Ruei-Nian Li, Tsan-Teng Ou, Chia-Hui Lin, Yuan-Zhao Lin, Tzu-Jung Fang, Yi-Jing Chen, Chia-Chun Tseng, Wan-Yu Sung, Cheng-Chin Wu, Jeng-Hsien Yen
Publikováno v:
Diagnostics, Vol 13, Iss 2, p 206 (2023)
Aim: The activation of NLRP3 inflammasome leads to the stimulation of cytokines and is significantly involved in the pathogenesis and progression of autoimmune diseases. The purpose of this study is to examine the associations of NLRP3 gene polymorph
Externí odkaz:
https://doaj.org/article/66b65c2c1d3b4026ba904e7939a4895d
Autor:
Wan-Yu Sung, Yuan-Zhao Lin, Daw-Yang Hwang, Chia-Hui Lin, Ruei-Nian Li, Chia-Chun Tseng, Cheng-Chin Wu, Tsan-Teng Ou, Jeng-Hsien Yen
Publikováno v:
Diagnostics, Vol 12, Iss 12, p 3006 (2022)
(1) Background: It is widely accepted that aberrant methylation patterns contribute to the development of systemic lupus erythematosus (SLE). Ten–eleven translocation (TET) methylcytosine dioxygenase is an essential enzyme of which there are three
Externí odkaz:
https://doaj.org/article/f520d6bfde4f4423af56c6b75e39286b
Autor:
Yi-Jing Chen, Wei-Chun Hung, Yu-Hsiang Chou, Chern-Hsiung Lai, Po Peng, Pei-Syuan Jhou, Min-Ru Tsai, Jim Jinn-Chyuan Sheu, Jeng-Hsien Yen
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9883 (2022)
Rheumatoid arthritis (RA) and periodontitis are suggested to be closely linked based on microbial dysbiosis, but limited subgingival bacteria have been proven in the pathogenesis of RA. We enrolled 30 RA patients and 25 controls and divided them into
Externí odkaz:
https://doaj.org/article/2e817644ce044fdf8f95ecff9e70cc1f
Autor:
Chia-Chun Tseng, Chung-Jen Chen, Jeng-Hsien Yen, Hsi-Yuan Huang, Jan-Gowth Chang, Shun-Jen Chang, Wei-Ting Liao
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-13 (2018)
Abstract Background Accumulating evidence implicates mitochondrial DNA (mtDNA) alleles, which are independent of the nuclear genome, in disease, especially in human metabolic diseases. However, this area of investigation has lagged behind in research
Externí odkaz:
https://doaj.org/article/a6c474c52a54431abcdfab66acd9914c
Autor:
Tzu-Hsuan Wong, Chon-Lin Lee, Hsiang-Han Su, Chin-Lai Lee, Chao-Chien Wu, Chin-Chou Wang, Chau-Chyun Sheu, Ruay-Sheng Lai, Sum-Yee Leung, Chi-Cheng Lin, Yu-Feng Wei, Chien-Jen Wang, Yu-Chun Lin, Hua-Ling Chen, Ming-Shyan Huang, Jeng-Hsien Yen, Shau-Ku Huang, Jau-Ling Suen
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract Chronic exposure to ambient polycyclic aromatic hydrocarbons (PAHs) is associated with asthma, but its regulatory mechanisms remain incompletely defined. We report herein that elevated levels of urinary 1-hydroxypyrene, a biomarker of PAH ex
Externí odkaz:
https://doaj.org/article/a0379ce7611248c0a83dc40bde2a7d25
Autor:
Chia-Chun Tseng, Man-Chun Wong, Wei-Ting Liao, Chung-Jen Chen, Su-Chen Lee, Jeng-Hsien Yen, Shun-Jen Chang
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8, p 4187 (2021)
Variants of transcription factor binding sites (TFBSs) constitute an important part of the human genome. Current evidence demonstrates close links between nucleotides within TFBSs and gene expression. There are multiple pathways through which genomic
Externí odkaz:
https://doaj.org/article/51c3b78d98074e57b139b4c560cb5b4e
Autor:
Chia-Chun Tseng, Man Chun Wong, Wei-Ting Liao, Chung-Jen Chen, Su-Chen Lee, Jeng-Hsien Yen, Shun-Jen Chang
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 13, p 4702 (2020)
Current knowledge of gout centers on hyperuricemia. Relatively little is known regarding the pathogenesis of gouty inflammation. To investigate the epigenetic background of gouty inflammation independent of hyperuricemia and its relationship to genet
Externí odkaz:
https://doaj.org/article/19fce8d75bb84b46a175dd2d9d1c69fd