Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Jeng-Hsien Yen"'
Autor:
Chang‐Yi Yen, Pin‐Yi Wang, Kuan‐Yu Chen, Chia‐Chun Tseng, Cheng‐Chin Wu, Tsan‐Teng Ou, Jeng‐Hsien Yen
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 10, Pp 934-941 (2024)
Abstract Different human leukocyte antigen (HLA) genotypes have been known to be associated with the risk of development of Sjögren's syndrome in different populations, but this association has never been reported in Taiwan. We enrolled 1044 subject
Externí odkaz:
https://doaj.org/article/39119719b7e4410abb9bf217aa4f2fff
Publikováno v:
JMIR Formative Research, Vol 8, p e58048 (2024)
BackgroundMaintaining physical function and preserving spinal flexibility have been challenging in managing ankylosing spondylitis (AS). Most rehabilitation programs, including manual therapy, massage, hydrotherapy, and acupuncture, cannot be perform
Externí odkaz:
https://doaj.org/article/20f2620a36314220883140f6ae881ade
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 5, Pp 489-498 (2024)
Abstract Large cohort studies have disclosed the association between obesity and rheumatoid arthritis (RA) risk. The sarcopenia prevalence in RA patients can be up to 31%. However, there is little information linking adipokines to sarcopenia in RA, s
Externí odkaz:
https://doaj.org/article/1127807041ad4400b617ccbdd7d7cda1
Autor:
Tzu-Jung Fang, Chia-Hui Lin, Yuan-Zhao Lin, Min-HSi Chiu, Ruei-Nian Li, Hua-Chen Chan, Yao-Tsung Yeh, Jeng-Hsien Yen
Publikováno v:
Journal of the Formosan Medical Association, Vol 121, Iss 8, Pp 1431-1441 (2022)
Background/purpose: Recent studies showed that Histone deacetylases 6 (HDAC6) inhibitors could improve arthritis in rheumatoid arthritis (RA) rodent models, whereas lower HDAC6 expression was observed in RA patients’ synovial fibroblasts, raising t
Externí odkaz:
https://doaj.org/article/0e6c1ea7c4934211be745c8e88414d08
Autor:
Ruei-Nian Li, Tsan-Teng Ou, Chia-Hui Lin, Yuan-Zhao Lin, Tzu-Jung Fang, Yi-Jing Chen, Chia-Chun Tseng, Wan-Yu Sung, Cheng-Chin Wu, Jeng-Hsien Yen
Publikováno v:
Diagnostics, Vol 13, Iss 2, p 206 (2023)
Aim: The activation of NLRP3 inflammasome leads to the stimulation of cytokines and is significantly involved in the pathogenesis and progression of autoimmune diseases. The purpose of this study is to examine the associations of NLRP3 gene polymorph
Externí odkaz:
https://doaj.org/article/66b65c2c1d3b4026ba904e7939a4895d
Autor:
Wan-Yu Sung, Yuan-Zhao Lin, Daw-Yang Hwang, Chia-Hui Lin, Ruei-Nian Li, Chia-Chun Tseng, Cheng-Chin Wu, Tsan-Teng Ou, Jeng-Hsien Yen
Publikováno v:
Diagnostics, Vol 12, Iss 12, p 3006 (2022)
(1) Background: It is widely accepted that aberrant methylation patterns contribute to the development of systemic lupus erythematosus (SLE). Ten–eleven translocation (TET) methylcytosine dioxygenase is an essential enzyme of which there are three
Externí odkaz:
https://doaj.org/article/f520d6bfde4f4423af56c6b75e39286b
Autor:
Chia-Chun Tseng, Chung-Jen Chen, Jeng-Hsien Yen, Hsi-Yuan Huang, Jan-Gowth Chang, Shun-Jen Chang, Wei-Ting Liao
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-13 (2018)
Abstract Background Accumulating evidence implicates mitochondrial DNA (mtDNA) alleles, which are independent of the nuclear genome, in disease, especially in human metabolic diseases. However, this area of investigation has lagged behind in research
Externí odkaz:
https://doaj.org/article/a6c474c52a54431abcdfab66acd9914c
Autor:
Tzu-Hsuan Wong, Chon-Lin Lee, Hsiang-Han Su, Chin-Lai Lee, Chao-Chien Wu, Chin-Chou Wang, Chau-Chyun Sheu, Ruay-Sheng Lai, Sum-Yee Leung, Chi-Cheng Lin, Yu-Feng Wei, Chien-Jen Wang, Yu-Chun Lin, Hua-Ling Chen, Ming-Shyan Huang, Jeng-Hsien Yen, Shau-Ku Huang, Jau-Ling Suen
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract Chronic exposure to ambient polycyclic aromatic hydrocarbons (PAHs) is associated with asthma, but its regulatory mechanisms remain incompletely defined. We report herein that elevated levels of urinary 1-hydroxypyrene, a biomarker of PAH ex
Externí odkaz:
https://doaj.org/article/a0379ce7611248c0a83dc40bde2a7d25
Autor:
Chia-Chun Tseng, Ling-Yu Wu, Wen-Chan Tsai, Tsan-Teng Ou, Cheng-Chin Wu, Wan-Yu Sung, Po-Lin Kuo, Jeng-Hsien Yen
Publikováno v:
Diagnostics, Vol 9, Iss 3, p 98 (2019)
Using next-generation sequencing to decipher the molecular mechanisms underlying aberrant rheumatoid arthritis synovial fibroblasts (RASF) activation, we performed transcriptome-wide RNA-seq and small RNA-seq on synovial fibroblasts from rheumatoid a
Externí odkaz:
https://doaj.org/article/dc115a5856ad4a8f94934b0ce33197b1
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168919 (2016)
Dendritic cells (DCs) are critical for instructing immune responses toward inflammatory or anti-inflammatory status. Heme oxygenase-1 (HO-1) is known for its cytoprotective effect against oxidative stress and inflammation, suggesting its immune regul
Externí odkaz:
https://doaj.org/article/ab69e155c976417499aaac27c9336961