Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jeng Chang Lee"'
Autor:
Huai Chueh Chiang, Cheng Che Lee, Yueh Feng Lee, Han Wei Huang, Szu Jung Chen, Yu Min Yeh, Li Hsien Chen, Jang Yang Chang, Bo Wen Lin, Chou Ching K. Lin, Meng Ru Shen, Peng Chan Lin, Jeng Chang Lee
Publikováno v:
Theranostics
Rationale: Oxaliplatin-induced peripheral neuropathy (OIPN) is a common adverse effect that causes delayed treatment and poor prognosis among colorectal cancer (CRC) patients. However, its mechanism remains elusive, and no effective treatment is avai
Autor:
Po-Chen Chu, Jeng Chang Lee, Yih Jyh Lin, Kuen Tyng Lin, Chen Ching-Shih, Peng Chan Lin, Christina Wu, Tanios Bekaii-Saab, Chung Ta Lee, Hsing Yu Wu
Publikováno v:
Oncogene. 37:3440-3455
Although the role of insulin-like growth factor-I receptor (IGF-IR) in promoting colorectal liver metastasis is known, the mechanism by which IGF-IR is upregulated in colorectal cancer (CRC) is not defined. In this study, we obtained evidence that mu
Autor:
Szu-Jung Chen, Li-Hsien Chen, Yu-Min Yeh, Chou-Ching K Lin, Peng-Chan Lin, Han-Wei Huang, Meng-Ru Shen, Bo-Wen Lin, Jeng-Chang Lee, Cheng-Che Lee, Yueh-Feng Lee, Huai-Chueh Chiang, Jang-Yang Chang
Publikováno v:
Theranostics; 2021, Vol. 11 Issue 10, p4672-4687, 16p
Publikováno v:
FEBS Letters. 586:2260-2266
In nucleus, eIF4E regulates the nucleus export of specific mRNA. In this study, altered 4E-BP3 (eIF4E-binding protein 3) expression resulted in profoundly affected cyclin D1 protein levels, partially due to changes in the cytoplasmic cyclin D1 mRNA l
Autor:
Chao Jung Tsao, Pei Jung Lu, Ai Li Shiau, Kun Tu Yeh, Jan-Gowth Chang, Yih Huei Uen, Yin Hsun Feng, Chao Liang Wu, Jeng Chang Lee
Publikováno v:
Cancer Biology & Therapy. 11:111-121
Sprouty protein is a novel feedback regulator involved in downstream inactivation of several growth factor receptor pathways. Sprouty2 (Spry2) protein was shown to be downregulated in human cancers. High levels of microRNA-21 (miRNA-21) expression ha
Publikováno v:
Hu li za zhi The journal of nursing. 58(2)
Resection through an anal sphincter-saving (ASS) operation may affect a low rectal cancer patient'snormal defecation function. The long and complex reconstruction process following such a procedure makes understanding the patient rehabilitation exper
Autor:
Pei Jung Lu, Chao Jung Tsao, Gia Shing Shieh, Jeng Chang Lee, Kun Tu Yeh, Ai Li Shiau, Yin Hsun Feng, Chao Liang Wu, Jan-Gowth Chang
Publikováno v:
Cancer science. 101(9)
Sprouty2 (Spry2) is known to increase the expression of epidermal growth factor receptors (EGFR) by conjugating with c-Casitas B-lineage lymphoma (C-Cbl) to decrease protein degradation. The effect of Spry2 on the treatment of gefitinib, a tyrosine k
Autor:
Jeng Chang Lee, Ya Ping Chen, Ying Ju Chen, Yi-Wen Liu, Tzeng Horng Leu, Yao Wen Liu, Yi Chao Lee, Bo Wen Lin, Tai Chien Huang, Liang Yi Hung, Joseph T. Tseng, Wen Chang Chang, Chien Hsien Lai
Publikováno v:
Journal of Cellular and Molecular Medicine
Abnormal expression of Aurora-A and epidermal growth factor receptor (EGFR) is observed in different kinds of cancer and associated with poor prognosis in cancer patients. However, the relationship between Aurora-A and EGFR in tumour development was
Autor:
Lo-Ti Tsao, Shen-Jeu Won, Shiow-Hwa Day, Yi-Chen Lin, Jeng-Chang Lee, Mei-Lin Tsai, Chun-Nan Lin, Mei-Ing Chung, Horng-Huey Ko, Jih-Pyang Wang
Publikováno v:
Journal of natural products. 65(3)
A new lignan glycoside, 4-O-alpha-L-arabinopyranosyl-(1' "-->2' ')-beta-D-apiofuranosyldiphyllin (2), named procumbenoside A, and 11 known compounds were isolated from the whole plant of Justicia procumbens. The structure of 2 was established by spec
Publikováno v:
World journal of surgery. 25(3)
Angiogenesis is of vital importance during the development and progression of solid tumors. Vascular endothelial growth factor (VEGF) is a major regulator of angiogenesis and could be produced by some cancer cells. To investigate the clinical relevan