Zobrazeno 1 - 10
of 229
pro vyhledávání: '"Jenefer M Blackwell"'
Autor:
Rachael Lappan, Cajsa Classon, Shashi Kumar, Om Prakash Singh, Ricardo V de Almeida, Jaya Chakravarty, Poonam Kumari, Sangeeta Kansal, Shyam Sundar, Jenefer M Blackwell
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 9, p e0007444 (2019)
Visceral leishmaniasis (VL) caused by Leishmania donovani remains of public health concern in rural India. Those at risk of VL are also at risk of other neglected tropical diseases (NTDs) including soil transmitted helminths. Intestinal helminths are
Externí odkaz:
https://doaj.org/article/5a91551cf5d84ee28325e1658abc094f
Autor:
Michaela Fakiola, Om Prakash Singh, Genevieve Syn, Toolika Singh, Bhawana Singh, Jaya Chakravarty, Shyam Sundar, Jenefer M Blackwell
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 8, p e0007673 (2019)
Amphotericin B provides improved therapy for visceral leishmaniasis (VL) caused by Leishmania donovani, with single dose liposomal-encapsulated Ambisome providing the best cure rates. The VL elimination program aims to reduce the incidence rate in th
Externí odkaz:
https://doaj.org/article/22bf23feb15b42699e79bb956f3eab4e
Autor:
Jaya Chakravarty, Epco Hasker, Sangeeta Kansal, Om Prakash Singh, Paritosh Malaviya, Abhishek Kumar Singh, Ankita Chourasia, Toolika Singh, Medhavi Sudarshan, Akhil Pratap Singh, Bhawana Singh, Rudra Pratap Singh, Bart Ostyn, Michaela Fakiola, Albert Picado, Joris Menten, Jenefer M Blackwell, Mary E Wilson, David Sacks, Marleen Boelaert, Shyam Sundar
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 3, p e0007216 (2019)
BACKGROUND:Asymptomatic Leishmania donovani infections outnumber clinical presentations, however the predictors for development of active disease are not well known. We aimed to identify serological, immunological and genetic markers for progression
Externí odkaz:
https://doaj.org/article/6242884481ed4d80a4e523cd6bf58445
Autor:
Donporn Riyapa, Darawan Rinchai, Veerachat Muangsombut, Chayanin Wuttinontananchai, Mohammed Toufiq, Damien Chaussabel, Manabu Ato, Jenefer M Blackwell, Sunee Korbsrisate
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221016 (2019)
Neutrophil extracellular traps (NETs) are a recently identified, web-like, extracellular structure composed of decondensed nuclear DNA and associated antimicrobial granules. NETs are extruded into the extracellular environment via the reactive oxygen
Externí odkaz:
https://doaj.org/article/5165f9a526304a13980e940f56f62cf6
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 113, Iss 6 (2018)
Toxoplasma gondii uses epigenetic mechanisms to regulate both endogenous and host cell gene expression. To identify genes with putative epigenetic functions, we developed an in silico pipeline to interrogate the T. gondii proteome of 8313 proteins. S
Externí odkaz:
https://doaj.org/article/21fb74d79beb4431927b58634ef6b469
Autor:
Alba L Peixoto-Rangel, E Nancy Miller, Léa Castellucci, Sarra E Jamieson, Ricardo Guerra Peixe, Liliani de Souza Elias, Rodrigo Correa-Oliveira, Lílian MG Bahia-Oliveira, Jenefer M Blackwell
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 104, Iss 8, Pp 1187-1190 (2009)
Toxoplasma gondii infection is an important mediator of ocular disease in Brazil more frequently than reported from elsewhere. Infection and pathology are characterized by a strong proinflammatory response which in mice is triggered by interaction of
Externí odkaz:
https://doaj.org/article/fc571dd8c5ad4560b3d9ba6bd54d6a41
Autor:
Sarra E Jamieson, Heather Cordell, Eskild Petersen, Rima McLeod, Ruth E Gilbert, Jenefer M Blackwell
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 104, Iss 2, Pp 162-169 (2009)
Analysing human genetic variation provides a powerful tool in understanding risk factors for disease. Toxoplasma gondii acquired by the mother can be transmitted to the fetus. Infants with the most severe clinical signs in brain and eye are those inf
Externí odkaz:
https://doaj.org/article/4df9736314b34d2aa38c36d20cfe33eb
Autor:
Denise Anderson, Heather J Cordell, Michaela Fakiola, Richard W Francis, Genevieve Syn, Elizabeth S H Scaman, Elizabeth Davis, Simon J Miles, Toby McLeay, Sarra E Jamieson, Jenefer M Blackwell
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119333 (2015)
A body mass index (BMI) >22kg/m2 is a risk factor for type 2 diabetes (T2D) in Aboriginal Australians. To identify loci associated with BMI and T2D we undertook a genome-wide association study using 1,075,436 quality-controlled single nucleotide poly
Externí odkaz:
https://doaj.org/article/4a4a7d6a36d24e1f85dc0d45e1a4b795
Autor:
Jakris Eu-Ahsunthornwattana, E Nancy Miller, Michaela Fakiola, Wellcome Trust Case Control Consortium, Selma M B Jeronimo, Jenefer M Blackwell, Heather J Cordell
Publikováno v:
PLoS Genetics, Vol 10, Iss 7, p e1004445 (2014)
Approaches based on linear mixed models (LMMs) have recently gained popularity for modelling population substructure and relatedness in genome-wide association studies. In the last few years, a bewildering variety of different LMM methods/software pa
Externí odkaz:
https://doaj.org/article/f2b4e35645e24b3a8e7485c6a613a9e4
Autor:
Marie S Rye, Nicole M Warrington, Elizabeth S H Scaman, Shyan Vijayasekaran, Harvey L Coates, Denise Anderson, Craig E Pennell, Jenefer M Blackwell, Sarra E Jamieson
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48215 (2012)
BACKGROUND: Otitis media (OM) is a common childhood disease characterised by middle ear inflammation and effusion. Susceptibility to recurrent acute OM (rAOM; ≥ 3 episodes of AOM in 6 months) and chronic OM with effusion (COME; MEE ≥ 3 months) is
Externí odkaz:
https://doaj.org/article/871b8bef397b4efab4c8395143b27ab9