Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jency L. Showker"'
Autor:
Chen Chen, Nicole J. Mitchell, Jean Gratz, Eric R. Houpt, Yunyun Gong, Patricia A. Egner, John D. Groopman, Ronald T. Riley, Jency L. Showker, Erling Svensen, Estomih R. Mduma, Crystal L. Patil, Felicia Wu
Publikováno v:
Environment International, Vol 115, Iss , Pp 29-37 (2018)
Growth impairment is a major public health issue for children in Tanzania. The question remains as to whether dietary mycotoxins play a role in compromising children's growth. We examined children's exposures to dietary aflatoxin and fumonisin and po
Externí odkaz:
https://doaj.org/article/b2998ac3080b41718997cce7522eef3e
Autor:
Joyce R. Maddox, Janee Gelineau-van Waes, Andrew J. Sachs, Nicole M. Gardner, Kenneth A. Voss, Ronald T. Riley, Jency L. Showker
Publikováno v:
Toxicological Sciences. 150:161-168
FTY720 (fingolimod) is a U.S. Food and Drug Administration-approved drug to treat relapsing remitting multiple sclerosis. FTY720 treatment in pregnant inbred LM/Bc mice results in approximately 60% of embryos having a neural tube defect (NTD). Sphing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::932de61de14efc24d6509a063910d47d
https://doi.org/10.1093/toxsci/kfv321
https://doi.org/10.1093/toxsci/kfv321
Autor:
Allison E. Ashley-Koch, Jency L. Showker, Joyce R. Maddox, Simon G. Gregory, Janee Gelineau-van Waes, Olga Torres, Jorge Matute, Ronald T. Riley, Kenneth A. Voss, Trevor R. Mitchell
Publikováno v:
Molecular Nutrition & Food Research. 59:2209-2224
Scope Fumonisin (FB) occurs in maize and is an inhibitor of ceramide synthase (CerS). We determined the urinary FB1 (UFB1) and sphingoid base 1-phosphate levels in blood from women consuming maize in high and low FB exposure communities in Guatemala.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcb1850291ba6277c8ee98f5a1d89fb9
https://doi.org/10.1002/mnfr.201500499
https://doi.org/10.1002/mnfr.201500499
Autor:
Allison E. Ashley-Koch, Joyce R. Maddox, Simon G. Gregory, J. Gelineau-van Waes, Olga Torres, Jorge Matute, Ronald T. Riley, Jency L. Showker, Kenneth A. Voss
Publikováno v:
World Mycotoxin Journal. 8:143-159
Co-occurrence of fumonisin B1 (FB1) and aflatoxin B1 (AFB1) in maize has been demonstrated in many surveys. Combined-exposure to FB1 and AFB1 was of concern to the Joint FAO/WHO Expert Committee on Food Additives because of the known genotoxicity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53dac2c3f368e6f36fb55f8881bc0d4d
https://doi.org/10.3920/wmj2014.1736
https://doi.org/10.3920/wmj2014.1736
Autor:
Allison E. Ashley-Koch, Simon G. Gregory, Joyce R. Maddox, Jorge Matute, Janee Gelineau-van Waes, Ronald T. Riley, Nicholas C. Zitomer, Jency L. Showker, Olga Torres, Kenneth A. Voss
Publikováno v:
Molecular Nutrition & Food Research. 58:973-983
Scope Fumonisin (FB) intake can be high when maize is a dietary staple. We determined (i) urinary FB (UFB) in women consuming maize in high- and low-exposure communities in Guatemala, (ii) the FB levels in maize, (iii) the relationship between UFB an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b45cdedd5a7cf6f088362c791e5b1581
https://doi.org/10.1002/mnfr.201300481
https://doi.org/10.1002/mnfr.201300481
Autor:
Jency L. Showker, Janee Gelineau-van Waes, Andrew J. Sachs, Nicole M. Gardner, Joyce R. Maddox, Kenneth A. Voss, Ronald T. Riley
Publikováno v:
Toxicology and applied pharmacology. 298
Fumonisin B1 (FB1) is a mycotoxin produced by a common fungal contaminant of corn. Administration of FB1 to pregnant LM/Bc mice induces exencephaly in embryos, and ingestion of FB1-contaminated food during early pregnancy is associated with increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c3357c26f82914c5a0f57469ba507f3
https://pubmed.ncbi.nlm.nih.gov/26905748
https://pubmed.ncbi.nlm.nih.gov/26905748
Autor:
Christine M. Lee, Kenneth A. Voss, Janee Gelineau-van Waes, Nicholas C. Zitomer, Jency L. Showker, Olga Torres, Jorge Matute, Trevor R. Mitchell, Ronald T. Riley, Allison E. Ashley-Koch, Nicole M. Gardner, Cody E. Zipperer, Simon G. Gregory, Joyce R. Maddox
Publikováno v:
Food additivescontaminants. Part A, Chemistry, analysis, control, exposurerisk assessment. 32(6)
Fumonisins (FB) are mycotoxins found in maize. They are hypothesized risk factors for neural tube defects (NTDs) in humans living where maize is a dietary staple. In LM/Bc mice, FB1-treatment of pregnant dams induces NTDs and results in increased lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4419eaf691fe0b3c3bebc28977db9a6
https://pubmed.ncbi.nlm.nih.gov/25833119
https://pubmed.ncbi.nlm.nih.gov/25833119
Publikováno v:
Food and Chemical Toxicology. 43:123-131
Fumonisin B 1 (FB 1 ) is a fungal toxin produced by Fusarium verticillioides that inhibits ceramide synthase (CS), a key enzyme in the de novo sphingolipid biosynthesis pathway. In LLC-PK 1 cells, FB 1 inhibits cell proliferation and induces apoptosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5269258971b8888d6e77ba23cfe172
https://doi.org/10.1016/j.fct.2004.09.001
https://doi.org/10.1016/j.fct.2004.09.001
Publikováno v:
Environmental Toxicology and Pharmacology. 3:221-228
Fumonisin B(1), B(2), and B(3) are inhibitors of ceramide synthase, a key enzyme in the pathway for de novo sphingolipid biosynthesis. Corn, naturally contaminated with either predominantly fumonisin B(1) or pure fumonisin B(1), has been shown to cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::520c7a12904185e81d0e2c16e8aee1db
https://doi.org/10.1016/s1382-6689(97)00015-x
https://doi.org/10.1016/s1382-6689(97)00015-x
Publikováno v:
Toxicology and Applied Pharmacology. 138:211-218
Fumonisin B1 is an inhibitor of ceramide synthase, a key enzyme in de novo sphingolipid biosynthesis and reacylation of free sphingosine. The purpose of this study was to determine the contribution of increased intracellular free sphinganine and decr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed2fe1a6a79d630f6df26360ead3ee3
https://doi.org/10.1006/taap.1996.0119
https://doi.org/10.1006/taap.1996.0119