Clinical predictors of poor outcomes in patients with sickle cell disease and COVID-19 infection

Autor: Mehdi Nouraie, Michael U. Callaghan, Ahmar U. Zaidi, Caterina P. Minniti, Victor R. Gordeuk, Charleen Jacobs, Elizabeth S. Klings, Jeffrey Glassberg, Jena Simon, Sarah Carpenter, Andrew Crouch, Jin Han, Deepa Manwani, Gary D. Crouch

Publikováno v: Blood Advances

Key Points SCD patients with COVID-19 display a broad range of severity, with a higher case fatality than the non-SCD population (10.9% vs 3.3%). Older patients not treated with hydroxyurea with end organ damage who present with acute kidney injury,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b6b47f3487bd71ad365b4a03be702b
https://doi.org/10.1182/bloodadvances.2020003456

Developing an emergency department order set to treat acute pain in sickle cell disease

Autor: Sarah N Gibbs, Kaedrea Jackson, Dana Shani, Irina Yermilov, Bonnie Brown, Michael S. Broder, Sally Liang, Jena Simon, Tartania Brown, David O. Beenhouwer, Melanie Malloy, Yves Duroseau, Marie-Laure Romney

Publikováno v: Journal of the American College of Emergency Physicians Open
Journal of the American College of Emergency Physicians Open, Vol 2, Iss 4, Pp n/a-n/a (2021)

Study Objective Patients with sickle cell disease (SCD) have many emergency department visits because of painful vaso‐occlusive episodes (VOE). Guidelines recommend treatment within 30 minutes of triage, but this is rarely achieved in clinical prac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d02f845da9bd5d42524836432c7d5b
https://pubmed.ncbi.nlm.nih.gov/34401866

Integration of Mobile Health Into Sickle Cell Disease Care to Increase Hydroxyurea Utilization: Protocol for an Efficacy and Implementation Study

Autor: Theodore Wun, Cathy L. Melvin, Lisa DiMartino, Cecelia Calhoun, Marsha Treadwell, Nirmish Shah, Ana A. Baumann, Victor R. Gordeuk, Robert W. Gibson, Donald Brambilla, Michael B. Potter, Jane S. Hankins, Jena Simon, Hayden B. Bosworth, Richard Lottenberg, Abdullah Kutlar, Maria E. Fernandez, Lisa M. Klesges

Publikováno v: JMIR Research Protocols, Vol 9, Iss 7, p e16319 (2020)
JMIR Research Protocols

Background Hydroxyurea prevents disease complications among patients with sickle cell disease (SCD). Although its efficacy has been endorsed by the National Health Lung and Blood Institute evidence-based guidelines, its adoption is low, both by patie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::838afc1dbd81f873ac8a8e9f65a96ed1
https://www.researchprotocols.org/2020/7/e16319

Derivation and preliminary validation of a risk score to predict 30-day ED revisits for sickle cell pain

Autor: Jordan M. Jeong, Gary Yu, Jena Simon, Nilesh Patel, Justin J. McNamee, Jeffrey Glassberg

Publikováno v: The American Journal of Emergency Medicine. 33:1396-1401

Background Emergency department (ED) revisits and 30-day readmissions have been proposed as markers for quality of ED care for sickle cell disease (SCD). Objective To create a scoring system that quantifies the risk of 30-day revisit after ED dischar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3abee57151cc99f2f0923d5bfa308c12
https://doi.org/10.1016/j.ajem.2015.07.015

Bayesian analyses demonstrate tissue blood volume is not decreased during acute sickle cell pain episodes: A preliminary study

Autor: Daniel S. Gareau, Jeffrey Glassberg, Jena Simon, Maria Perry

BACKGROUND Pain is the most common complication of Sickle Cell Disease (SCD). Tissue oximetry properties in SCD during steady state and acute pain are not well described. METHODS This was a cross sectional study of tissue oximetry properties in indiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50bd02b9c712fb5976e2b81e646e4013
https://europepmc.org/articles/PMC4515395/