Zobrazeno 1 - 10
of 302
pro vyhledávání: '"Jen-Tsan Chi"'
Autor:
Yanting Chen, Xiaohan Lu, Raeann L. Whitney, Yu Li, Matthew J. Robson, Randy D. Blakely, Jen-Tsan Chi, Steven D. Crowley, Jamie R. Privratsky
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Introduction: Acute kidney injury (AKI) is one of the most common causes of organ failure in critically ill patients. Following AKI, the canonical pro-inflammatory cytokine interleukin-1β (IL-1β) is released predominantly from activated myeloid cel
Externí odkaz:
https://doaj.org/article/c578873524ba41d090b5725020c8e311
Autor:
Duc T. Huynh, Kalina N. Tsolova, Abigail J. Watson, Sai Kwan Khal, Jordan R. Green, Di Li, Jimin Hu, Erik J. Soderblom, Jen-Tsan Chi, Chantell S. Evans, Michael Boyce
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The neurofilament (NF) cytoskeleton is critical for neuronal morphology and function. In particular, the neurofilament-light (NF-L) subunit is required for NF assembly in vivo and is mutated in subtypes of Charcot-Marie-Tooth (CMT) disease.
Externí odkaz:
https://doaj.org/article/bc888ee5fb374fb2a241843afc353ebd
Publikováno v:
Cancers, Vol 16, Iss 11, p 1991 (2024)
Prostate cancer (PC) stands as the most frequently diagnosed non-skin cancer and ranks as the second highest cause of cancer-related deaths among men in the United States. For those facing non-metastatic PC necessitating intervention, solely local tr
Externí odkaz:
https://doaj.org/article/9349ec9c55594335a884a2d5f6eeddb1
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 475 (2024)
Our previous study discovered that sucrose and other non-reducing sugars (e.g., trehalose and raffinose) could be used to improve the electrotransfer (ET) of molecular cargo, including DNA, mRNA, and ribonucleoprotein in various cell lines and primar
Externí odkaz:
https://doaj.org/article/2a45578b4ec54febbb88f01310716e67
Publikováno v:
Data in Brief, Vol 47, Iss , Pp 108938- (2023)
MESH1 is the metazoan homolog of bacterial SpoT, the main phosphatase that dephosphorylates and degrades (p)ppGpp, the alarmone involved in the bacterial stringent response. The functional role of MESH1 in human cells is unknown. To define the global
Externí odkaz:
https://doaj.org/article/424338ccd95f47388840f61b8930e32f
Autor:
Jen-Tsan Chi, Pei Zhou
Publikováno v:
PLoS Pathogens, Vol 19, Iss 2, p e1011105 (2023)
Externí odkaz:
https://doaj.org/article/5db0c3852de445f398f2935dc7331275
Autor:
Tianai Sun, Chien-Kuang Cornelia Ding, Yuning Zhang, Yang Zhang, Chao-Chieh Lin, Jianli Wu, Yasaman Setayeshpour, Si’Ana Coggins, Caitlin Shepard, Everardo Macias, Baek Kim, Pei Zhou, Raluca Gordân, Jen-Tsan Chi
Publikováno v:
Cell Death and Disease, Vol 13, Iss 3, Pp 1-24 (2022)
Abstract All organisms are constantly exposed to various stresses, necessitating adaptive strategies for survival. In bacteria, the main stress-coping mechanism is the stringent response triggered by the accumulation of “alarmone” (p)ppGpp to arr
Externí odkaz:
https://doaj.org/article/7a49a4d8b7594d4a8a1846204b4d39c6
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 2680-2684 (2022)
All organisms are constantly exposed to various stresses, necessitating adaptive strategies for survival. In bacteria, the main metabolic stress-coping mechanism is the stringent response, which is triggered by the accumulation of “alarmone” (p)p
Externí odkaz:
https://doaj.org/article/512a5d0c1b06429ea32740b9fcd67f64
Publikováno v:
Cancers, Vol 15, Iss 15, p 3861 (2023)
Given the enormous suffering and death associated with human cancers, there is an urgent need for novel therapeutic approaches to target tumor growth and metastasis. While initial efforts have focused on the dysregulated oncogenic program of cancer c
Externí odkaz:
https://doaj.org/article/5545196d461c42249e52241a316d9ae5
Autor:
Chao-Chieh Lin, Chien-Kuang Cornelia Ding, Tianai Sun, Jianli Wu, Kai-Yuan Chen, Pei Zhou, Jen-Tsan Chi
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-10 (2021)
Abstract All organisms exposed to metabolic and environmental stresses have developed various stress adaptive strategies to maintain homeostasis. The main bacterial stress survival mechanism is the stringent response triggered by the accumulation “
Externí odkaz:
https://doaj.org/article/150a25f87ae44ccaa6345387880b3114