Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jen-Fei Chu"'
Publikováno v:
Cell Reports, Vol 29, Iss 10, Pp 3118-3133.e6 (2019)
Summary: Tightly regulated transport of messenger ribonucleoprotein (mRNP) granules to diverse locations of dendrites and axons is essential for appropriately timed protein synthesis within distinct sub-neuronal compartments. Perturbations of this re
Externí odkaz:
https://doaj.org/article/46f22ac3dbba47c282612cf9c27b263b
Publikováno v:
Acta neuropathologica, vol 132, iss 5
Acta Neuropathologica
Acta Neuropathologica
For proper mammalian brain development and functioning, the translation of many neuronal mRNAs needs to be repressed without neuronal activity stimulations. We have discovered that the expression of a subclass of neuronal proteins essential for neuro
Publikováno v:
Cell Reports, Vol 29, Iss 10, Pp 3118-3133.e6 (2019)
Summary: Tightly regulated transport of messenger ribonucleoprotein (mRNP) granules to diverse locations of dendrites and axons is essential for appropriately timed protein synthesis within distinct sub-neuronal compartments. Perturbations of this re
Publikováno v:
SSRN Electronic Journal.
Tightly regulated transport of mRNAs in the form of mRNP granules to diverse locations of the dendrites and axons is essential for timed protein synthesis within distinct sub-neuronal compartments. Perturbations in this regulation lead to neurodevelo
Publikováno v:
Journal of the Chinese Chemical Society. 58:296-300
We present a simple method based on the Cu2+ induced unfolding of G-quadruplex (G4) of human telomere sequence d[AG3(T2AG3)3] to screen a number of 3,6-bis(1-methyl-4-vinylpyridinium)carbazole diiodide (BMVC) analogues for better G4 stabilizers. Usin
Publikováno v:
Biophysical Journal. 98:1608-1616
Human telomere contains guanine-rich (G-rich) tandem repeats of single-stranded DNA sequences at its 3′ tail. The G-rich sequences can be folded into various secondary structures, termed G-quadruplexes (G4s), by Hoogsteen basepairing in the presenc
Publikováno v:
Journal of Luminescence. :84-90
Fluorescence studies of 3,6-bis(1-methyl-4-vinylpyridinium) carbazole diiodide (BMVC) in glycerol/water mixtures allow us to elucidate the photophysical behavior of BMVC upon interaction with different DNA structures. The very weak fluorescence emiss
Publikováno v:
Analytical biochemistry. 436(2)
G-quadruplexes are stable secondary structures formed by Hoogsteen base pairing of guanine-rich single-stranded DNA sequences in the presence of monovalent cations (Na(+) or K(+)). Folded G-quadruplex (G4) structures in human telomeres have been prop
Publikováno v:
Current pharmaceutical design. 18(14)
The challenge of G-quadruplexes is that the G-rich sequences can adopt various G4 structures and possibly interconvert among them, particularly under the change of environmental conditions. Both NMR and circular dichroism (CD) show the spectral conve
Autor:
Jen-Fei Chu, 朱任飛
99
Telomeres, the ends of eukaryotic chromosomes, are essential for the stability of chromosomes. In the presence of monovalent cations such as Na+ or K+, the G-rich single stranded DNA of telomere can form a secondary structure through Hoogstee
Telomeres, the ends of eukaryotic chromosomes, are essential for the stability of chromosomes. In the presence of monovalent cations such as Na+ or K+, the G-rich single stranded DNA of telomere can form a secondary structure through Hoogstee
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/58708977636518496108