Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Jen Yi Lee"'
Autor:
Lan-Hui Li, Ping Wu, Jen-Yi Lee, Pei-Rong Li, Wan-Yu Hsieh, Chao-Chi Ho, Chen-Lung Ho, Wan-Jiun Chen, Chien-Chun Wang, Muh-Yong Yen, Shun-Min Yang, Huei-Wen Chen
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104203 (2014)
Despite good initial responses, drug resistance and disease recurrence remain major issues for lung adenocarcinoma patients with epidermal growth factor receptor (EGFR) mutations taking EGFR-tyrosine kinase inhibitors (TKI). To discover new strategie
Externí odkaz:
https://doaj.org/article/f38d989bcd034b2b82b732db08a8e9e6
Autor:
Jen-Yi Lee, Yee-Ming Lee, Gee-Chen Chang, Sung-Liang Yu, Wan-Yu Hsieh, Jeremy J W Chen, Huei-Wen Chen, Pan-Chyr Yang
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23756 (2011)
BACKGROUND: Non-small cell lung cancer (NSCLC) patients with L858R or exon 19 deletion mutations in epidermal growth factor receptor (EGFR) have good responses to the tyrosine kinase inhibitor (TKI), gefitinib. However, patients with wild-type EGFR a
Externí odkaz:
https://doaj.org/article/f84e5b0eb3d0446091e72c4b9239a5ea
Autor:
George Stratigopoulos, Ross M. Tanis, Holly L. Aaron, Nicolas F. Berbari, Richard Rausch, Dieter Egli, Manika Purohit, Claudia A. Doege, Kathryn E. Birkenbach, Jerica Tan, Xueting Li, Liheng Wang, Alain J. De Solis, Gabriela J. Martins, Jacob M. Levenson, Rui M. Costa, Jen-Yi Lee, Maria Caterina De Rosa, Yossef Goffer, Rudolph L. Leibel, Jens C. Brüning, Staci E. Engle
Publikováno v:
JCI insight, vol 4, iss 3
Intronic polymorphisms in the α-ketoglutarate-dependent dioxygenase gene (FTO) that are highly associated with increased body weight have been implicated in the transcriptional control of a nearby ciliary gene, retinitis pigmentosa GTPase regulator-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4242183bea06f0394e3c3ab0e0d1e50
https://doi.org/10.1172/jci.insight.123337
https://doi.org/10.1172/jci.insight.123337
Autor:
Jen-Yi Lee, Maiko Kitaoka
Publikováno v:
Molecular biology of the cell. 29(13)
Fluorescence light microscopy is an indispensable approach for the investigation of cell biological mechanisms. With the development of cutting-edge tools such as genetically encoded fluorescent proteins and superresolution methods, light microscopy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e415f4953bb5a7ce172191ea21d6939
https://pubmed.ncbi.nlm.nih.gov/29953344
https://pubmed.ncbi.nlm.nih.gov/29953344
Autor:
Jen Yi Lee, Sheng-Chu Kuo, Hsin Yi Hung, Li Lin, Qian Shi, Hui-Wen Chen, Yu Zhao, Koji Wada, Pan-Chyr Yang, Masuo Goto, Kuo Hsiung Lee
Publikováno v:
Bioorganic & Medicinal Chemistry. 23:1507-1514
Curcumin (1) down-regulates the expression as well as phosphorylation of epidermal growth factor receptor (EGFR) in lung adenocarcinoma cells expressing gefitinib-resistant EGFR. Thirty-seven newly synthesized curcumin analogues including dimethoxycu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51dcb286e0f11e3c1dbd682239a9ea7b
https://doi.org/10.1016/j.bmc.2015.02.003
https://doi.org/10.1016/j.bmc.2015.02.003
Autor:
Sung-Liang Yu, Yu-Shuang Lin, Ya-Chien Yang, Qi-Sheng Hong, Munisamy Sureshbabul, Chun-Chieh Chen, Jen-Yi Lee, Huei-Wen Chen
Publikováno v:
Evidence-Based Complementary and Alternative Medicine, Vol 2013 (2013)
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-based Complementary and Alternative Medicine : eCAM
Colorectal cancer (CRC) is a serious public health problem that results due to changes of diet and various environmental stress factors in the world. Curcumin is a traditional medicine used for treatment of a wide variety of tumors. However, antimeta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::092a08d9d0ab3c96c4a3424d296b5078
https://doi.org/10.1155/2013/541695
https://doi.org/10.1155/2013/541695
Autor:
Jen-Yi Lee
Publikováno v:
Wiley Interdisciplinary Reviews: Developmental Biology. 1:286-293
Bottle cell-driven blastopore lip formation externally marks the initiation of gastrulation in amphibian embryos. The blastopore groove is formed when bottle cells undergo apical constriction and transform from cuboidal to flask-shaped. Apical constr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e6c54e1e4587f504e53d6b2ea812c74
https://doi.org/10.1002/wdev.19
https://doi.org/10.1002/wdev.19
Publikováno v:
Development. 137:3337-3345
The axis of asymmetric cell division is controlled to determine the future position of differentiated cells during animal development. The asymmetric localization of PAR proteins in the Drosophila neuroblast and C. elegans embryo are aligned with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13df536fbfb629bb6441072fe13619b9
https://doi.org/10.1242/dev.054742
https://doi.org/10.1242/dev.054742
Autor:
Wan-Jiun Chen, Chi-Chung Wang, Jeremy J.W. Chen, Jen-Yi Lee, Pan-Chyr Yang, Huei-Wen Chen, Meng-Feng Tsai, Ji-Ying Huang, Sung-Liang Yu, Chia-Wen Huang, Sheng-Fang Su, Chao-Chi Ho
Publikováno v:
Cancer Research. 68:7428-7438
Curcumin (diferuloylmethane) is an active component of the spice turmeric and has a diversity of antitumor activities. In this study, we found that curcumin can inhibit cancer cell invasion and metastasis through activation of the tumor suppressor Dn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::715b7b676f805c189b7c684dbfa34c0f
https://doi.org/10.1158/0008-5472.can-07-6734
https://doi.org/10.1158/0008-5472.can-07-6734
Autor:
Richard M. Harland, Jen-Yi Lee
Publikováno v:
Developmental Biology. 311(1):40-52
Cell shape changes are critical for morphogenetic events such as gastrulation, neurulation, and organogenesis. However, the cell biology driving cell shape changes is poorly understood, especially in vertebrates. The beginning of Xenopus laevis gastr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ddf187c526c29583a0137674f1d5035