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pro vyhledávání: '"Jen Quick-Cleveland"'
Publikováno v:
Cell Reports, Vol 7, Iss 6, Pp 1994-2005 (2014)
Canonical primary microRNA transcripts (pri-miRNAs) are characterized by a ∼30 bp hairpin flanked by single-stranded regions. These pri-miRNAs are recognized and cleaved by the Microprocessor complex consisting of the Drosha nuclease and its obliga
Externí odkaz:
https://doaj.org/article/a04e1f2a41384f83b98665871da5d383
Publikováno v:
RNA (New York, N.Y.), vol 27, iss 12
Understanding transcriptomes requires documenting the structures, modifications, and abundances of RNAs as well as their proximity to other molecules. The methods that make this possible depend critically on enzymes (including mutant derivatives) tha
Autor:
Jen Quick-Cleveland, Sara H. Weitz, Shimon Weiss, Jose Jacob, Kikuye Koyano, Xinshu Xiao, Feng Guo, Ian G. Barr, Rachel Senturia
The essential biological cofactor heme is synthesized in cells in the Fe(II) form. Oxidized Fe(III) heme is specifically required for processing primary transcripts of microRNAs (pri-miRNAs) by the RNA-binding protein DGCR8, a core component of the M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2f3765188eb2dae8deedfbe91c1e283
Publikováno v:
Cell reports, vol 7, iss 6
Cell Reports, Vol 7, Iss 6, Pp 1994-2005 (2014)
Quick-Cleveland, J; Jacob, JP; Weitz, SH; Shoffner, G; Senturia, R; & Guo, F. (2014). The DGCR8 RNA-Binding Heme Domain Recognizes Primary MicroRNAs by Clamping the Hairpin. Cell Reports, 7(6), 1994-2005. doi: 10.1016/j.celrep.2014.05.013. UCLA: Retrieved from: http://www.escholarship.org/uc/item/2rw6m6jt
Cell Reports, Vol 7, Iss 6, Pp 1994-2005 (2014)
Quick-Cleveland, J; Jacob, JP; Weitz, SH; Shoffner, G; Senturia, R; & Guo, F. (2014). The DGCR8 RNA-Binding Heme Domain Recognizes Primary MicroRNAs by Clamping the Hairpin. Cell Reports, 7(6), 1994-2005. doi: 10.1016/j.celrep.2014.05.013. UCLA: Retrieved from: http://www.escholarship.org/uc/item/2rw6m6jt
Canonical primary microRNA transcripts (pri-miRNAs) are characterized by a ~30bp hairpin flanked by single-stranded regions. These pri-miRNAs are recognized and cleaved by the Microprocessor complex consisting of the Drosha nuclease and its obligate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c384938c32c1dd823eeec331760ff3d9
https://escholarship.org/uc/item/2rw6m6jt
https://escholarship.org/uc/item/2rw6m6jt