Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jen C C Hume"'
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20156 (2011)
Vector susceptibility to Plasmodium infection is treated primarily as a vector trait, although it is a composite trait expressing the joint occurrence of the parasite and the vector with genetic contributions of both. A comprehensive approach to asse
Externí odkaz:
https://doaj.org/article/1451e35b1c6d4fc39479d92176fbf6fb
Autor:
Alexandra Schwarz, Stefan Helling, Nicolas Collin, Clarissa R Teixeira, Nora Medrano-Mercado, Jen C C Hume, Teresa C Assumpção, Katrin Marcus, Christian Stephan, Helmut E Meyer, José M C Ribeiro, Peter F Billingsley, Jesus G Valenzuela, Jeremy M Sternberg, Günter A Schaub
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 3, Iss 10, p e532 (2009)
Triatomines are vectors of Trypanosoma cruzi, the etiological agent of Chagas disease in Latin America. The most effective vector, Triatoma infestans, has been controlled successfully in much of Latin America using insecticide spraying. Though rarely
Externí odkaz:
https://doaj.org/article/732f8323dfca4b108d9ad7784850bcd4
Autor:
Tovi Lehmann, Jen C C Hume, Monica Licht, Christopher S Burns, Kurt Wollenberg, Fred Simard, Jose' M C Ribeiro
Publikováno v:
PLoS ONE, Vol 4, Iss 2, p e4549 (2009)
As pathogens that circumvent the host immune response are favoured by selection, so are host alleles that reduce parasite load. Such evolutionary processes leave their signature on the genes involved. Deciphering modes of selection operating on immun
Externí odkaz:
https://doaj.org/article/2e9f042f430e4ff89895766343d2531d
Autor:
Thayne H. Dickey, Richi Gupta, Holly McAleese, Tarik Ouahes, Sachy Orr-Gonzalez, Rui Ma, Olga Muratova, Nichole D. Salinas, Jen C. C. Hume, Lynn E. Lambert, Patrick E. Duffy, Niraj H. Tolia
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-10 (2023)
Abstract A malaria vaccine that blocks parasite transmission from human to mosquito would be a powerful method of disrupting the parasite lifecycle and reducing the incidence of disease in humans. Pfs48/45 is a promising antigen in development as a t
Externí odkaz:
https://doaj.org/article/08492bc9918f41c297b57ea2d425e412
Autor:
Sumana Chakravarty, Eric R. James, Stephen L. Hoffman, Lei K. Ding, Jillian Neal, Charles Wyatt, Sahand Kalhori, Anita Manoj, Alemush Imeru, Omely Marte-Salcedo, Sangeeta N. Bhatia, Hope Decederfelt, David M. Cook, Agnes Mwakingwe-Omari, Martha Nason, Jen C. C. Hume, Sara A. Healy, Aarti Kolluri, Natasha Kc, Ijeoma Ikpeama, B. Kim Lee Sim, Peter F. Billingsley, Sean C. Murphy, L. W. Preston Church, Jihyun E. Jeon, Sandra March, Grace K. Lee, Irfan Zaidi, Jacob Raiten, Junhui Duan, Anusha Gunasekera, Thomas L. Richie, Tooba Murshedkar, Jacquelyn Lane, Patrick E. Duffy, Charles Anderson
Publikováno v:
Nature. 595:289-294
The global decline in malaria has stalled1, emphasizing the need for vaccines that induce durable sterilizing immunity. Here we optimized regimens for chemoprophylaxis vaccination (CVac), for which aseptic, purified, cryopreserved, infectious Plasmod
Autor:
Rebecca Barney, Allison Golden, Ihn Kyung Yang, Mahamadoun H. Assadou, Merepen A. Guindo, Patrick E. Duffy, Issaka Sagara, Jen C. C. Hume, Emily N. Reichert, Sara A. Healy, Hannah C Slater, Andy Rashid, Gonzalo J. Domingo
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-10 (2020)
Malaria Journal
Malaria Journal
Background The recent expansion of tools designed to accurately quantify malaria parasite-produced antigens has enabled us to evaluate the performance of rapid diagnostic tests (RDTs) as a function of the antigens they detect—typically histidine ri
Autor:
Elizabeth B. Brickley, Sekou F. Traore, Jen C. C. Hume, Erin E. Gabriel, Issaka Sagara, Ogobara K. Doumbo, Sara A. Healy, Mamadou B. Coulibaly, Patrick E. Duffy
Publikováno v:
Vaccine. 34:5863-5870
Shifting the malaria priorities from a paradigm of control and elimination to a goal of global eradication calls for renewed attention to the interruption of malaria transmission. Sustained progress toward eradication will require both improved under
Autor:
Steve Kuntz, Patrick E. Duffy, Sara A. Healy, Anna Wald, Stefan H. I. Kappe, Jen C. C. Hume, Ruobing Wang, Sean R. Marcsisin, Angela K Talley, Mark Kennedy, Richa Chaturvedi, Olivia C Finney, Kenneth Stuart, Sean C. Murphy, Barbara Metch, Lisa Shelton, Sharon Wong-Madden, Margaret Warner-Lubin, Matthew Fishbaugher, Wesley C. Van Voorhis, Charlotte V. Hobbs, James G. Kublin, Zoe Moodie, Tiffany Silver-Brace
Publikováno v:
Clin Infect Dis
Background Chemoprophylaxis vaccination with sporozoites (CVac) with chloroquine induces protection against a homologous Plasmodium falciparum sporozoite (PfSPZ) challenge, but whether blood-stage parasite exposure is required for protection remains
Autor:
Mamadou B, Coulibaly, Erin E, Gabriel, Youssouf, Sinaba, Daman, Sylla, Adama, Sacko, Lakamy, Sylla, Boubacar, Coulibaly, Jen C C, Hume, Ibrahima, Baber, Mahamadoun H, Assadou, Issaka, Sagara, Yimin, Wu, Sara A, Healy, Ogobara, Doumbo, Sekou F, Traore, Patrick E, Duffy
Publikováno v:
The American journal of tropical medicine and hygiene. 97(3)
Malaria transmission-blocking vaccines (TBV) have been evaluated in field trials in Mali since 2013. However, the assays currently used to measure serum antibody TB activity (TBA) after vaccination are highly variable, in part due to the lack of opti
Autor:
Ibrahima Baber, Ogobara K. Doumbo, Jen C. C. Hume, Sara A. Healy, Mamadou B. Coulibaly, Patrick E. Duffy, Youssouf Sinaba, Lakamy Sylla, Issaka Sagara, Boubacar Coulibaly, Mahamadoun Hamady Assadou, Daman Sylla, Sekou F. Traore, Yimin Wu, Adama Sacko, Erin E. Gabriel
Publikováno v:
American Journal of Tropical Medicine and Hygiene
American Journal of Tropical Medicine and Hygiene, American Society of Tropical Medicine and Hygiene, 2017, 97 (3), pp.719-725. ⟨10.4269/ajtmh.16-1000⟩
American Journal of Tropical Medicine and Hygiene, American Society of Tropical Medicine and Hygiene, 2017, 97 (3), pp.719-725. ⟨10.4269/ajtmh.16-1000⟩
International audience; Malaria transmission-blocking vaccines (TBV) have been evaluated in field trials in Mali since 2013. However, the assays currently used to measure serum antibody TB activity (TBA) after vaccination are highly variable, in part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abd9f01f1391b85211f1ed558b0d04c
https://www.hal.inserm.fr/inserm-01980300/document
https://www.hal.inserm.fr/inserm-01980300/document