Zobrazeno 1 - 10
of 301
pro vyhledávání: '"Jen‐Tsan Chi"'
Autor:
Ssu-Yu Chen, Jianli Wu, Yubin Chen, Ya-En Wang, Yasaman Setayeshpour, Chiara Federico, Alexander A. Mestre, Chao-Chieh Lin, Jen-Tsan Chi
Publikováno v:
Cell Death and Disease, Vol 15, Iss 10, Pp 1-12 (2024)
Abstract Ninjurin-1 (NINJ1), initially identified as a stress-induced protein in neurons, recently emerged as a key mediator of plasma membrane rupture (PMR) during apoptosis, necrosis, and pyroptosis. However, its involvement in ferroptosis is less
Externí odkaz:
https://doaj.org/article/77c8c3393fa543f4a5ee7ed2cfcac0ae
Autor:
Yanting Chen, Xiaohan Lu, Raeann L. Whitney, Yu Li, Matthew J. Robson, Randy D. Blakely, Jen-Tsan Chi, Steven D. Crowley, Jamie R. Privratsky
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Introduction: Acute kidney injury (AKI) is one of the most common causes of organ failure in critically ill patients. Following AKI, the canonical pro-inflammatory cytokine interleukin-1β (IL-1β) is released predominantly from activated myeloid cel
Externí odkaz:
https://doaj.org/article/c578873524ba41d090b5725020c8e311
Autor:
Duc T. Huynh, Kalina N. Tsolova, Abigail J. Watson, Sai Kwan Khal, Jordan R. Green, Di Li, Jimin Hu, Erik J. Soderblom, Jen-Tsan Chi, Chantell S. Evans, Michael Boyce
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The neurofilament (NF) cytoskeleton is critical for neuronal morphology and function. In particular, the neurofilament-light (NF-L) subunit is required for NF assembly in vivo and is mutated in subtypes of Charcot-Marie-Tooth (CMT) disease.
Externí odkaz:
https://doaj.org/article/bc888ee5fb374fb2a241843afc353ebd
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 475 (2024)
Our previous study discovered that sucrose and other non-reducing sugars (e.g., trehalose and raffinose) could be used to improve the electrotransfer (ET) of molecular cargo, including DNA, mRNA, and ribonucleoprotein in various cell lines and primar
Externí odkaz:
https://doaj.org/article/2a45578b4ec54febbb88f01310716e67
Publikováno v:
Data in Brief, Vol 47, Iss , Pp 108938- (2023)
MESH1 is the metazoan homolog of bacterial SpoT, the main phosphatase that dephosphorylates and degrades (p)ppGpp, the alarmone involved in the bacterial stringent response. The functional role of MESH1 in human cells is unknown. To define the global
Externí odkaz:
https://doaj.org/article/424338ccd95f47388840f61b8930e32f
Autor:
Jen-Tsan Chi, Pei Zhou
Publikováno v:
PLoS Pathogens, Vol 19, Iss 2, p e1011105 (2023)
Externí odkaz:
https://doaj.org/article/5db0c3852de445f398f2935dc7331275
Autor:
Tianai Sun, Chien-Kuang Cornelia Ding, Yuning Zhang, Yang Zhang, Chao-Chieh Lin, Jianli Wu, Yasaman Setayeshpour, Si’Ana Coggins, Caitlin Shepard, Everardo Macias, Baek Kim, Pei Zhou, Raluca Gordân, Jen-Tsan Chi
Publikováno v:
Cell Death and Disease, Vol 13, Iss 3, Pp 1-24 (2022)
Abstract All organisms are constantly exposed to various stresses, necessitating adaptive strategies for survival. In bacteria, the main stress-coping mechanism is the stringent response triggered by the accumulation of “alarmone” (p)ppGpp to arr
Externí odkaz:
https://doaj.org/article/7a49a4d8b7594d4a8a1846204b4d39c6
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 2680-2684 (2022)
All organisms are constantly exposed to various stresses, necessitating adaptive strategies for survival. In bacteria, the main metabolic stress-coping mechanism is the stringent response, which is triggered by the accumulation of “alarmone” (p)p
Externí odkaz:
https://doaj.org/article/512a5d0c1b06429ea32740b9fcd67f64
Autor:
Chao-Chieh Lin, Chien-Kuang Cornelia Ding, Tianai Sun, Jianli Wu, Kai-Yuan Chen, Pei Zhou, Jen-Tsan Chi
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-10 (2021)
Abstract All organisms exposed to metabolic and environmental stresses have developed various stress adaptive strategies to maintain homeostasis. The main bacterial stress survival mechanism is the stringent response triggered by the accumulation “
Externí odkaz:
https://doaj.org/article/150a25f87ae44ccaa6345387880b3114
Autor:
Eui Jung Moon, Stephano S. Mello, Caiyun G. Li, Jen-Tsan Chi, Kaushik Thakkar, Jacob G. Kirkland, Edward L. Lagory, Ik Jae Lee, Anh N. Diep, Yu Miao, Marjan Rafat, Marta Vilalta, Laura Castellini, Adam J. Krieg, Edward E. Graves, Laura D. Attardi, Amato J. Giaccia
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Hypoxia plays a critical role in tumor progression including invasion and metastasis. Here, the authors screened several hypoxia inducible genes and identified the oncogenic role of MAFF in breast cancer metastasis and that it activates IL11/STAT3 pa
Externí odkaz:
https://doaj.org/article/74a0bdf041f848a69bf653962a2ec1b4