Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Jen, Liou"'
Publikováno v:
Contact, Vol 4 (2021)
Recent studies indicated potential importance of membrane contact sites (MCS) between the endoplasmic reticulum (ER) and other cellular organelles. These MCS have unique protein and lipid composition and serve as hubs for inter-organelle communicatio
Externí odkaz:
https://doaj.org/article/85e80d5d11694b199f37b584528026fb
Autor:
Vladimir Zhemkov, Jonathon A Ditlev, Wan-Ru Lee, Mikaela Wilson, Jen Liou, Michael K Rosen, Ilya Bezprozvanny
Publikováno v:
eLife, Vol 10 (2021)
Sigma 1 receptor (S1R) is a 223-amino-acid-long transmembrane endoplasmic reticulum (ER) protein. S1R modulates activity of multiple effector proteins and is a well-established drug target. However, signaling functions of S1R in cells are poorly unde
Externí odkaz:
https://doaj.org/article/151f396a8d22489085371cbc83db875d
Autor:
Suneeta Chimalapati, Marcela de Souza Santos, Alexander E Lafrance, Ann Ray, Wan-Ru Lee, Giomar Rivera-Cancel, Gonçalo Vale, Krzysztof Pawlowski, Matthew A Mitsche, Jeffrey G McDonald, Jen Liou, Kim Orth
Publikováno v:
eLife, Vol 9 (2020)
Pathogens find diverse niches for survival including inside a host cell where replication occurs in a relatively protective environment. Vibrio parahaemolyticus is a facultative intracellular pathogen that uses its type 3 secretion system 2 (T3SS2) t
Externí odkaz:
https://doaj.org/article/a8424b4b04004c88957a624611019e5f
Publikováno v:
Nature Immunology. 24:136-147
Hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) by phospholipase C-γ (PLCγ1) represents a critical step in T cell antigen receptor (TCR) signaling and subsequent thymocyte and T cell responses. PIP2 replenishment following its depletion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97a76bdd367405dd307d65b372dee49e
https://doi.org/10.1038/s41590-022-01372-2
https://doi.org/10.1038/s41590-022-01372-2
Publikováno v:
eLife, Vol 8 (2019)
RET is a receptor tyrosine kinase (RTK) that plays essential roles in development and has been implicated in several human diseases. Different from most of RTKs, RET requires not only its cognate ligands but also co-receptors for activation, the mech
Externí odkaz:
https://doaj.org/article/9170d56b942a49c3bc5ccdc2d8982bc2
Autor:
Hsin-Yi Hung, Shih-Min Lin, Chia-Ying Li, Sio-Hong Lam, Yu-Yi Chan, Meei-Jen Liou, Po-Chuen Shieh, Fu-An Chen, Ping-Chung Kuo, Tian-Shung Wu
Publikováno v:
Molecules, Vol 26, Iss 6, p 1599 (2021)
A highly specific and sensitive proton nuclear magnetic resonance (1H-NMR) method has been developed for the quantification of ephedrine alkaloid derivatives in Ephedra herbal commercial prescriptions. At the region of δ 4.0 to 5.0 ppm in the 1H NMR
Externí odkaz:
https://doaj.org/article/eabfabf317174da59a3e6ed351297f85
Autor:
Jen Liou
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5174c7ac7274c35428c6c3ff9bf5a4d
https://doi.org/10.1096/fasebj.2022.36.s1.0i150
https://doi.org/10.1096/fasebj.2022.36.s1.0i150
Autor:
Chi-Lun Chang, Ting-Sung Hsieh, T. Tony Yang, Karen G. Rothberg, D. Berfin Azizoglu, Elzibeth Volk, Jung-Chi Liao, Jen Liou
Publikováno v:
Cell Reports, Vol 5, Iss 3, Pp 813-825 (2013)
Endoplasmic reticulum (ER)-plasma membrane (PM) junctions are highly conserved subcellular structures. Despite their importance in Ca2+ signaling and lipid trafficking, the molecular mechanisms underlying the regulation and functions of ER-PM junctio
Externí odkaz:
https://doaj.org/article/af9cb6ddd2564e449a564842957003c3
Publikováno v:
Molecular Biology of the Cell. 33
Plasma membrane (PM) phosphatidylinositol 4,5-bisphosphate (PIP2) homeostasis in stimulated cells is mediated by recruiting the lipid transfer protein Nir2 to endoplasmic reticulum (ER)–PM junctions. In this article, Nir1 is identified as a novel E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a05bd939f80d1e7c1526de7c88567397
https://doi.org/10.1091/mbc.e21-07-0356
https://doi.org/10.1091/mbc.e21-07-0356
Spatiotemporal regulation of NADP(H) phosphatase Nocturnin and its role in oxidative stress response
Autor:
Carla B. Green, Arianna Dino, Carlo Giovanni Quintanilla, Anushka Wickramaratne, Crystal A. Khan, Isara Laothamatas, Peng Gao, Jen Liou
Publikováno v:
Proc Natl Acad Sci U S A
An intimate link exists between circadian clocks and metabolism with nearly every metabolic pathway in the mammalian liver under circadian control. Circadian regulation of metabolism is largely driven by rhythmic transcriptional activation of clock-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99c90fed2c6432514e0cdaa734b3997b
https://doi.org/10.1073/pnas.1913712117
https://doi.org/10.1073/pnas.1913712117