Zobrazeno 1 - 10
of 553
pro vyhledávání: '"Jemth P."'
Autor:
Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract The virus life cycle depends on host-virus protein-protein interactions, which often involve a disordered protein region binding to a folded protein domain. Here, we used proteomic peptide phage display (ProP-PD) to identify peptides from th
Externí odkaz:
https://doaj.org/article/0dc8318509ba40b4a7a4978a68d342a6
Autor:
Si Min Zhang, Cynthia B.J. Paulin, Huazhang Shu, Miriam Yagüe-Capilla, Maurice Michel, Petra Marttila, Florian Ortis, Henri Colyn Bwanika, Christopher Dirks, Rajagopal Papagudi Venkatram, Elisée Wiita, Ann-Sofie Jemth, Ingrid Almlöf, Olga Loseva, Femke M. Hormann, Tobias Koolmeister, Erika Linde, Sun Lee, Sabin Llona-Minguez, Martin Haraldsson, Hanna Axelsson, Kia Strömberg, Evert J. Homan, Martin Scobie, Thomas Lundbäck, Thomas Helleday, Sean G. Rudd
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108907- (2024)
Summary: SAMHD1 is a dNTP triphosphohydrolase governing nucleotide pool homeostasis and can detoxify chemotherapy metabolites controlling their clinical responses. To understand SAMHD1 biology and investigate the potential of targeting SAMHD1 as neoa
Externí odkaz:
https://doaj.org/article/62a8b016c8c04843b50875f18c4706f6
Autor:
Filip Mihalič, Leandro Simonetti, Girolamo Giudice, Marie Rubin Sander, Richard Lindqvist, Marie Berit Akpiroro Peters, Caroline Benz, Eszter Kassa, Dilip Badgujar, Raviteja Inturi, Muhammad Ali, Izabella Krystkowiak, Ahmed Sayadi, Eva Andersson, Hanna Aronsson, Ola Söderberg, Doreen Dobritzsch, Evangelia Petsalaki, Anna K. Överby, Per Jemth, Norman E. Davey, Ylva Ivarsson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Viruses mimic host short linear motifs (SLiMs) to hijack and deregulate cellular functions. Studies of motif-mediated interactions therefore provide insight into virus-host dependencies, and reveal targets for therapeutic intervention. Here,
Externí odkaz:
https://doaj.org/article/e64e95cb96fe4ac196aaf0a9198064f8
Akademický článek
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Autor:
Arianne M Babina, Serhiy Surkov, Weihua Ye, Jon Jerlström-Hultqvist, Mårten Larsson, Erik Holmqvist, Per Jemth, Dan I Andersson, Michael Knopp
Publikováno v:
eLife, Vol 12 (2023)
Increasing numbers of small proteins with diverse physiological roles are being identified and characterized in both prokaryotic and eukaryotic systems, but the origins and evolution of these proteins remain unclear. Recent genomic sequence analyses
Externí odkaz:
https://doaj.org/article/ce91ea5a032a455499ccf3854d441846
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
Reconstruction of an ancient nuclear coactivator binding domain (NCBD) of CREB-binding protein from a bilaterian animal ancestor living 600 million years ago reveals conserved dynamic properties in human NCBD.
Externí odkaz:
https://doaj.org/article/b3678dcf1c654474a6663ba47b10204e
Autor:
Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 1, Pp 1-27 (2022)
Abstract Specific protein–protein interactions are central to all processes that underlie cell physiology. Numerous studies have together identified hundreds of thousands of human protein–protein interactions. However, many interactions remain to
Externí odkaz:
https://doaj.org/article/f6abadd527bf44d9a60e048c7d8b617c
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Thomas Kruse, Caroline Benz, Dimitriya H. Garvanska, Richard Lindqvist, Filip Mihalic, Fabian Coscia, Raviteja Inturi, Ahmed Sayadi, Leandro Simonetti, Emma Nilsson, Muhammad Ali, Johanna Kliche, Ainhoa Moliner Morro, Andreas Mund, Eva Andersson, Gerald McInerney, Matthias Mann, Per Jemth, Norman E. Davey, Anna K. Överby, Jakob Nilsson, Ylva Ivarsson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Many interactions between viral and host proteins are mediated by short peptide motifs. Here, using a phage-based viral peptide library, the authors identify 269 peptide-based interactions for 18 coronaviruses, including an interaction between SARS-C
Externí odkaz:
https://doaj.org/article/1f444706eff944aca145f8ed28412f90
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105069- (2022)
Summary: The post-synaptic density (PSD) is a phase-separated membraneless compartment of proteins including PSD-95 that undergoes morphological alteration in response to synaptic activity. Here, we investigated the interactome of a three-domain supr
Externí odkaz:
https://doaj.org/article/d1d7673496e94f97b27f0f51f2fef54f