Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Jemily Malvar"'
Autor:
Michael D. Keller, Patrick J. Hanley, Yueh-Yun Chi, Paibel Aguayo-Hiraldo, Christopher C. Dvorak, Michael R. Verneris, Donald B. Kohn, Sung-Yun Pai, Blachy J. Dávila Saldaña, Benjamin Hanisch, Troy C. Quigg, Roberta H. Adams, Ann Dahlberg, Shanmuganathan Chandrakasan, Hasibul Hasan, Jemily Malvar, Mariah A. Jensen-Wachspress, Christopher A. Lazarski, Gelina Sani, John M. Idso, Haili Lang, Pamela Chansky, Chase D. McCann, Jay Tanna, Allistair A. Abraham, Jennifer L. Webb, Abeer Shibli, Amy K. Keating, Prakash Satwani, Pawel Muranski, Erin Hall, Michael J. Eckrich, Evan Shereck, Holly Miller, Ewelina Mamcarz, Rajni Agarwal, Satiro N. De Oliveira, Mark T. Vander Lugt, Christen L. Ebens, Victor M. Aquino, Jeffrey J. Bednarski, Julia Chu, Suhag Parikh, Jennifer Whangbo, Michail Lionakis, Elias T. Zambidis, Elizabeth Gourdine, Catherine M. Bollard, Michael A. Pulsipher
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Viral infections remain a major risk in immunocompromised pediatric patients, and virus-specific T cell (VST) therapy has been successful for treatment of refractory viral infections in prior studies. We performed a phase II multicenter stud
Externí odkaz:
https://doaj.org/article/fcdca2f7424c452f994b7e545a14509b
Autor:
Christopher Kuo, Jemily Malvar, Yueh‐Yun Chi, Eugene S. Kim, Rachana Shah, Fariba Navid, James E. Stein, Leo Mascarenhas
Publikováno v:
Cancer Medicine, Vol 12, Iss 20, Pp 20231-20241 (2023)
Abstract Background Thoracotomy is considered the standard surgical approach for the management of pulmonary metastases in osteosarcoma (OST). Several studies have identified the advantages of a thoracoscopic approach, however, the clinical significa
Externí odkaz:
https://doaj.org/article/821cf3a111a54546a3ab218009f9d5a8
Autor:
Sally Cohen‐Cutler, Arthur Olch, Kenneth Wong, Jemily Malvar, Richard Sposto, Pierre Kobierski, Amit Sura, Louis S. Constine, David R. Freyer
Publikováno v:
Cancer Medicine, Vol 10, Iss 3, Pp 905-913 (2021)
ABSTRACT Background Radiation‐related screening guidelines for survivors of childhood cancer currently use irradiated regions (IR) to determine risk for late effects. However, contemporary radiotherapy techniques utilize volumetric dosimetry (VD) t
Externí odkaz:
https://doaj.org/article/a532515ba2724cf1813c8751aadbeac7
Autor:
Sarah K. Tasian, Lewis B. Silverman, James A. Whitlock, Richard Sposto, Joseph P. Loftus, Eric S. Schafer, Kirk R. Schultz, Raymond J. Hutchinson, Paul S. Gaynon, Etan Orgel, Caroline M. Bateman, Todd M. Cooper, Theodore W. Laetsch, Maria Luisa Sulis, Yueh-Yun Chi, Jemily Malvar, Alan S. Wayne, Susan R. Rheingold
Publikováno v:
Haematologica, Vol 107, Iss 10 (2022)
Phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) signaling is commonly dysregulated in acute lymphoblastic leukemia (ALL). The TACL2014-001 phase I trial of the mTOR inhibitor temsirolimus in combination with cyclophosphamide
Externí odkaz:
https://doaj.org/article/8445bc9f98404419b1d22c8a88c190ec
Autor:
Jianping Sun, Larry Wang, Michael John Zobel, Abigail K Zamora, Hong-wei Wu, Danny Lascano, Jemily Malvar, Michael A Sheard, Robert C Seeger, Eugene S Kim
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Immunotherapy with anti-disialoganglioside dinutuximab has improved survival for children with high-risk neuroblastoma (NB) when given after induction chemotherapy and surgery. However, disease recurrence and resistance persist. Dinutuxima
Externí odkaz:
https://doaj.org/article/bfe8dc20ceaf4f77a6534d0a408d1595
Autor:
Rie Nakata, Hiroyuki Shimada, G. Esteban Fernandez, Rob Fanter, Muller Fabbri, Jemily Malvar, Pascale Zimmermann, Yves A. DeClerck
Publikováno v:
Journal of Extracellular Vesicles, Vol 6, Iss 1 (2017)
The bone marrow (BM) niche is a microenvironment promoting survival, dormancy and therapeutic resistance in tumor cells. Central to this function are mesenchymal stromal cells (MSCs). Here, using neuroblastoma (NB) as a model, we demonstrate that NB
Externí odkaz:
https://doaj.org/article/a0faaa563f9543ae93f61de5ae2f307a
Publikováno v:
Journal of Clinical and Translational Science, Vol 2, Pp 37-37 (2018)
OBJECTIVES/SPECIFIC AIMS: Low cancer clinical trial (CCTs) enrollment may contribute to the poor survival improvement for adolescents and young adults (AYAs, aged 15–39 years) with cancer. Treatment site is thought to exacerbate this problem. This
Externí odkaz:
https://doaj.org/article/01d3028350d640df8da674abc22b883d
Autor:
Etan Orgel, Kristin R. Knight, Yueh-Yun Chi, Jemily Malvar, Teresa Rushing, Victoria Mena, Laurie S. Eisenberg, Shahrad R. Rassekh, Colin J.D. Ross, Erika N. Scott, Michael Neely, Edward A. Neuwelt, Leslie L. Muldoon, David R. Freyer
Publikováno v:
Clinical Cancer Research. :OF1-OF9
Purpose: Cisplatin-induced hearing loss (CIHL) is common and permanent. As compared with earlier otoprotectants, we hypothesized N-acetylcysteine (NAC) offers potential for stronger otoprotection through stimulation of glutathione (GSH) production. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24fc3a21c721fd467460a97d29a8c53e
https://doi.org/10.1158/1078-0432.ccr-23-0252
https://doi.org/10.1158/1078-0432.ccr-23-0252
Autor:
Kelly C. Goldsmith, Julie R. Park, Kimberly Kayser, Jemily Malvar, Yueh-Yun Chi, Susan G. Groshen, Judith G. Villablanca, Kateryna Krytska, Lillian M. Lai, Patricia T. Acharya, Fariba Goodarzian, Bruce Pawel, Hiroyuki Shimada, Susan Ghazarian, Lisa States, Lynley Marshall, Louis Chesler, Meaghan Granger, Ami V. Desai, Rajen Mody, Daniel A. Morgenstern, Suzanne Shusterman, Margaret E. Macy, Navin Pinto, Gudrun Schleiermacher, Kieuhoa Vo, Holger C. Thurm, Joseph Chen, Marlon Liyanage, Gerson Peltz, Katherine K. Matthay, Esther R. Berko, John M. Maris, Araz Marachelian, Yael P. Mossé
Publikováno v:
Nature Medicine. 29:1092-1102
Neuroblastomas harbor ALK aberrations clinically resistant to crizotinib yet sensitive pre-clinically to the third-generation ALK inhibitor lorlatinib. We conducted a first-in-child study evaluating lorlatinib with and without chemotherapy in childre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05cb1069b5caae85576f8251b56aaa50
https://doi.org/10.1038/s41591-023-02297-5
https://doi.org/10.1038/s41591-023-02297-5
Publikováno v:
Haemophilia. 29:100-105
Emicizumab is a humanized bispecific monoclonal antibody licensed for patients with severe haemophilia A. Breakthrough bleeding still occurs in patients on emicizumab and can be managed with recombinant factor VIIa (rFVIIa) or activated prothrombin c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff66879bbd504c7860b91cb1a7148ac3
https://doi.org/10.1111/hae.14684
https://doi.org/10.1111/hae.14684