Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jemila C. Kester"'
Autor:
Karen J Kieser, Cara C Boutte, Jemila C Kester, Christina E Baer, Amy K Barczak, Xavier Meniche, Michael C Chao, E Hesper Rego, Christopher M Sassetti, Sarah M Fortune, Eric J Rubin
Publikováno v:
PLoS Pathogens, Vol 11, Iss 6, p e1005010 (2015)
Cell growth and division are required for the progression of bacterial infections. Most rod-shaped bacteria grow by inserting new cell wall along their mid-section. However, mycobacteria, including the human pathogen Mycobacterium tuberculosis, produ
Externí odkaz:
https://doaj.org/article/765fe55a1c6d4311bb94f15f6f51c4b4
Autor:
Daniel A. Russell, J. A. Judd, Alexander Dills, Joseph T. Wade, Jemila C. Kester, M. Mir, Erica Lasek-Nesselquist, E. Dove, Sarah M. Fortune, Rebekah M. Dedrick, Pascal Lapierre, Christopher G Meier, Keith M. Derbyshire, Ian D. Wolf, A. Joseph, Ryan R Clark, M. Stone, Graham F. Hatfull, Jill G. Canestrari, Junhao Zhu, Todd A. Gray, Samantha E. Wirth, Ashutosh Upadhyay, E. R. Rubin, Michael J. Palumbo, Carol Smith
Publikováno v:
mBio
mBio, Vol 12, Iss 2 (2021)
mBio, Vol 12, Iss 2 (2021)
Diseases caused by mycobacterial species result in millions of deaths per year globally, and present a substantial health and economic burden, especially in immunocompromised patients. Difficulties inherent in working with mycobacterial pathogens hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26779fa33222648452693fc48bf4c821
http://europepmc.org/articles/PMC8092266
http://europepmc.org/articles/PMC8092266
Autor:
Yasu S. Morita, Todd A. Gray, James R Brenner, Sarah M. Fortune, Jemila C. Kester, Ian L Sparks, Keith M. Derbyshire, Julia Puffal, Brittany R Anderson, Alexander Dills, Joseph T. Wade, Julius Judd, Malavika Prithviraj, Corelle A. Z. Rokicki
Publikováno v:
J Bacteriol
Mycobacteria spatially organize their plasma membrane, and many enzymes involved in envelope biosynthesis associate with a membrane compartment termed the intracellular membrane domain (IMD). The IMD is concentrated in the polar regions of growing ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde5a52c8640f36fa0ebc31b89d8ab42
https://doi.org/10.1101/2021.02.17.431749
https://doi.org/10.1101/2021.02.17.431749
Autor:
Tatos Akopian, Junhao Zhu, Michael R. Chase, Olga Kandror, Jemila C. Kester, Alfred L. Goldberg, Eric J. Rubin, Sarah M. Fortune
Publikováno v:
Journal of Bacteriology
Tuberculosis, caused by Mycobacterium tuberculosis, imposes a major global health burden, surpassing HIV and malaria in annual deaths. The ClpP1P2 proteolytic complex and its cofactor ClpX are attractive drug targets, but their precise cellular funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04062d4a84b572b54e3fbc6593a2ac87
https://doi.org/10.1128/jb.00608-20
https://doi.org/10.1128/jb.00608-20
Autor:
Kirsten Schneider, David L. Trumper, Mao Taketani, Yu-Ja Huang, Brij Bhushan, Kyle Benton, Jun Young Yoon, Steven J. Holcomb, Jemila C. Kester, Linda G. Griffith, John Kemmitt, David Carpenter, Pierre Sphabmixay, George Eng, Ömer H. Yilmaz, Gar Rohatgi, Charles V. Wright, Victor Hernandez-Gordillo, Jianbo Zhang, David T. Breault, Christopher A. Voigt
Publikováno v:
Med (N Y)
Elsevier
Elsevier
Summary Background The gut microbiome plays an important role in human health and disease. Gnotobiotic animal and in vitro cell-based models provide some informative insights into mechanistic crosstalk. However, there is no existing system for a long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1599aed3d1ad9f64e2a24555e261fca
https://doi.org/10.1101/2020.07.02.185082
https://doi.org/10.1101/2020.07.02.185082
Autor:
Jason Velazquez, Jemila C. Kester, Linda G. Griffith, Douglas A. Lauffenburger, Douglas K. Brubaker, Charles V. Wright
Publikováno v:
American Society for Microbiology
Antimicrob Agents Chemother
Antimicrob Agents Chemother
A clinically relevant risk factor forClostridioides difficile-associated dis-ease (CDAD) is recent antibiotic treatment. Although broad-spectrum antibioticshave been shown to disrupt the structure of the gut microbiota, some antibioticsappear to incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea49dcb4e32236a91a61a6bb4431c7b1
https://hdl.handle.net/1721.1/124762
https://hdl.handle.net/1721.1/124762
Autor:
Jemila C. Kester, Linda G. Griffith, Douglas A. Lauffenburger, Douglas K. Brubaker, Charles V. Wright, Jason Velazquez
The most clinically relevant risk factor for Clostridioides difficile-associated disease (CDAD) is recent antibiotic treatment. Though most broad-spectrum antibiotics significantly disrupt the structure of the gut microbiota, only particular ones inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a1a05f0dc88846ea6f238c2e8f8909
Autor:
Elizabeth M. Ward, Wen Li Kelly Chen, Cristina Y. Zamora, Barbara Imperiali, Jemila C. Kester, Linda G. Griffith, Jason Velazquez
Publikováno v:
Glycobiology
An in vitro gut-immune co-culture model with apical and basal accessibility, designed to more closely resemble a human intestinal microenvironment, was employed to study the role of the N-linked protein glycosylation pathway in Campylobacter jejuni p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d3452d7ca6e3b729add005ed1a54d58
https://pubmed.ncbi.nlm.nih.gov/31965157
https://pubmed.ncbi.nlm.nih.gov/31965157
Autor:
Alfred L. Garfall, Alison K. Spencer, Vasilena Gocheva, Marsha L. Quick, Jemila C. Kester, Robert L. Bowman, Leila Akkari, Johanna A. Joyce
Publikováno v:
Genes and Development, vol. 30, no. 2, pp. 220-232
Proteases are important for regulating multiple tumorigenic processes, including angiogenesis, tumor growth, and invasion. Elevated protease expression is associated with poor patient prognosis across numerous tumor types. Several multigene protease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f810c9c89de5e9fcdba280b4411e1958
https://doi.org/10.1101/gad.270439.115
https://doi.org/10.1101/gad.270439.115
Autor:
Sarah M. Fortune, Jemila C. Kester
Publikováno v:
Critical Reviews in Biochemistry and Molecular Biology. 49:91-101
One of the challenges in clinical infectious diseases is the problem of chronic infections, which can require long durations of antibiotic treatment and often recur. An emerging explanation for the refractoriness of some infections to treatment is th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd98397ae3d537b6bbef0988c0730bb
https://doi.org/10.3109/10409238.2013.869543
https://doi.org/10.3109/10409238.2013.869543