Zobrazeno 1 - 10
of 348
pro vyhledávání: '"Jelske"'
Autor:
Natasha A. Trzaskalski, Branka Vulesevic, My-Anh Nguyen, Natasha Jeraj, Evgenia Fadzeyeva, Nadya M. Morrow, Cassandra A.A. Locatelli, Nicole Travis, Antonio A. Hanson, Julia R.C. Nunes, Conor O’Dwyer, Jelske N. van der Veen, Ilka Lorenzen-Schmidt, Rick Seymour, Serena M. Pulente, Andrew C. Clément, Angela M. Crawley, René L. Jacobs, Mary-Anne Doyle, Curtis L. Cooper, Kyoung-Han Kim, Morgan D. Fullerton, Erin E. Mulvihill
Publikováno v:
JCI Insight, Vol 8, Iss 2 (2023)
Elevated circulating dipeptidyl peptidase-4 (DPP4) is a biomarker for liver disease, but its involvement in gluconeogenesis and metabolic associated fatty liver disease progression remains unclear. Here, we identified that DPP4 in hepatocytes but not
Externí odkaz:
https://doaj.org/article/40cdcc7f6d5742ecbe16d60323de171c
Autor:
John P. Kennelly, Stephanie Carlin, Tingting Ju, Jelske N. van der Veen, Randal C. Nelson, Jean Buteau, Aducio Thiesen, Caroline Richard, Ben P. Willing, René L. Jacobs
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 999-1021 (2021)
Background & Aims: Patients with ulcerative colitis have low concentrations of the major membrane lipid phosphatidylcholine (PC) in gastrointestinal mucus, suggesting that defects in colonic PC metabolism might be involved in the development of colit
Externí odkaz:
https://doaj.org/article/13b401fe7615444286f1361c641b7deb
Autor:
Anita Ayer, Daniel J. Fazakerley, Cacang Suarna, Ghassan J. Maghzal, Diba Sheipouri, Kevin J. Lee, Michelle C. Bradley, Lucía Fernández-del-Rio, Sergey Tumanov, Stephanie MY. Kong, Jelske N. van der Veen, Andrian Yang, Joshua W.K. Ho, Steven G. Clarke, David E. James, Ian W. Dawes, Dennis E. Vance, Catherine F. Clarke, René L. Jacobs, Roland Stocker
Publikováno v:
Redox Biology, Vol 46, Iss , Pp 102127- (2021)
Mitochondrial energy production and function rely on optimal concentrations of the essential redox-active lipid, coenzyme Q (CoQ). CoQ deficiency results in mitochondrial dysfunction associated with increased mitochondrial oxidative stress and a rang
Externí odkaz:
https://doaj.org/article/e5e37048d10e4f0db080cc6d7d4696a3
Publikováno v:
Frontiers in Artificial Intelligence, Vol 4 (2021)
This paper investigates the usability of Twitter as a resource for the study of language change in progress in low-resource languages. It is a panel study of a vigorous change in progress, the loss of final t in four relative pronouns (dy't, dêr't,
Externí odkaz:
https://doaj.org/article/fd7fb664b61048d68e79ffbfd2b8bf39
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100093- (2021)
The liver is the central organ regulating cholesterol synthesis, storage, transport, and elimination. Mouse carboxylesterase 1d (Ces1d) and its human ortholog CES1 have been described to possess lipase activity and play roles in hepatic triacylglycer
Externí odkaz:
https://doaj.org/article/af94da54767141b7abd24b951a8c83f3
Autor:
John P. Kennelly, Jelske N. van der Veen, Randal C. Nelson, Kelly-Ann Leonard, Rick Havinga, Jean Buteau, Folkert Kuipers, René L. Jacobs
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 9, Pp 1695-1708 (2018)
De novo phosphatidylcholine (PC) synthesis via CTP:phosphocholine cytidylyltransferase-α (CTα) is required for VLDL secretion. To determine the precise role of de novo PC synthesis in intestinal lipid metabolism, we deleted CTα exclusively in the
Externí odkaz:
https://doaj.org/article/92c736a4f02e47748548008985011563
Autor:
Jelske N. van der Veen, Susanne Lingrell, Xia Gao, Abhijit Takawale, Zamaneh Kassiri, Dennis E. Vance, René L. Jacobs
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 4, Pp 656-667 (2017)
Mice lacking phosphatidylethanolamine N-methyltransferase (PEMT) are protected from high-fat diet (HFD)-induced obesity and insulin resistance. However, these mice develop severe nonalcoholic fatty liver disease (NAFLD) when fed the HFD, which is mai
Externí odkaz:
https://doaj.org/article/c58efff704c94360a34c5d02f2ebdb93
Autor:
Paul G. Kemps, Timo C. Zondag, Eline C. Steenwijk, Quirine Andriessen, Jelske Borst, Sandra Vloemans, Dave L. Roelen, Lenard M. Voortman, Robert M. Verdijk, Carel J. M. van Noesel, Arjen H. G. Cleven, Cynthia Hawkins, Veronica Lang, Arnoud H. de Ru, George M. C. Janssen, Geert W. Haasnoot, Kees L. M. C. Franken, Ronald van Eijk, Nienke Solleveld-Westerink, Tom van Wezel, R. Maarten Egeler, Auke Beishuizen, Jan A. M. van Laar, Oussama Abla, Cor van den Bos, Peter A. van Veelen, Astrid G. S. van Halteren
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Langerhans Cell Histiocytosis (LCH) is a neoplastic disorder of hematopoietic origin characterized by inflammatory lesions containing clonal histiocytes (LCH-cells) intermixed with various immune cells, including T cells. In 50–60% of LCH-patients,
Externí odkaz:
https://doaj.org/article/e72482c223694d18a86b7155b95eb24c
Uncertainty in the behavior of other traffic participants is a crucial factor in collision avoidance for automated driving; here, stochastic metrics could avoid overly conservative decisions. This paper introduces a Stochastic Model Predictive Contro
Externí odkaz:
http://arxiv.org/abs/2310.17381
Autor:
Xia Gao, Jelske N. van der Veen, Carlos Fernandez-Patron, Jean E. Vance, Dennis E. Vance, René L. Jacobs
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 9, Pp 1701-1710 (2015)
Mice that lack phosphatidylethanolamine N-methyltransferase (Pemt−/− mice) are protected from high-fat (HF) diet-induced obesity. HF-fed Pemt−/− mice show higher oxygen consumption and heat production, indicating that more energy might be uti
Externí odkaz:
https://doaj.org/article/465786c6169c45c49ba76e325b71c7a3