Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jelle Y. Broos"'
Autor:
Lisa JM Slimmen, Jelle Y Broos, Badies HAN Manaï, Silvia C Estevão, Martin Giera, Gijs Kooij, Wendy WJ Unger, Hettie M Janssens
Publikováno v:
Clinical & Translational Immunology, Vol 13, Iss 9, Pp n/a-n/a (2024)
Abstract Objectives In cystic fibrosis (CF), an imbalanced lipid metabolism is associated with lung inflammation. Little is known about the role that specific lipid mediators (LMs) exert in CF lung inflammation, and whether their levels change during
Externí odkaz:
https://doaj.org/article/4da749ba07244adea715809f78ff6e20
Autor:
Jelle Y. Broos, Rianne T. M. van der Burgt, Julia Konings, Merel Rijnsburger, Oliver Werz, Helga E. de Vries, Martin Giera, Gijs Kooij
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Background Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system (CNS), characterized by neuroinflammation, demyelination, and neurodegeneration. Considering the increasing prevalence among young adults worldw
Externí odkaz:
https://doaj.org/article/b8147a83a1be4f0c90161f152952badb
Autor:
Kitty Reemst, Jelle Y. Broos, Maralinde R. Abbink, Chiara Cimetti, Martin Giera, Gijs Kooij, Aniko Korosi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Brain lipid dysregulation is a hallmark of depression and Alzheimer’s disease, also marked by chronic inflammation. Early-life stress (ELS) and dietary intake of polyunsaturated fatty acids (PUFAs) are risk factors for these pathologies and are kno
Externí odkaz:
https://doaj.org/article/395dae8aad7e45b5abc4103bb25a9bcf
Autor:
Jeroen Baardman, Sanne G. S. Verberk, Saskia van der Velden, Marion J. J. Gijbels, Cindy P. P. A. van Roomen, Judith C. Sluimer, Jelle Y. Broos, Guillermo R. Griffith, Koen H. M. Prange, Michel van Weeghel, Soufyan Lakbir, Douwe Molenaar, Elisa Meinster, Annette E. Neele, Gijs Kooij, Helga E. de Vries, Esther Lutgens, Kathryn E. Wellen, Menno P. J. de Winther, Jan Van den Bossche
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Inhibition of the metabolic enzyme ATP-citrate lyase can attenuate atherosclerosis by preventing dyslipidemia and potentially also by reducing macrophage-mediated inflammation. Here, the authors show that specific targeting of ACLY in macrophages res
Externí odkaz:
https://doaj.org/article/2c0a011d044046398f11e576a0b58fa9
Autor:
Elien Grajchen, Melanie Loix, Paulien Baeten, Beatriz F. Côrte-Real, Ibrahim Hamad, Sam Vanherle, Mansour Haidar, Jonas Dehairs, Jelle Y. Broos, James M. Ntambi, Robert Zimmermann, Rolf Breinbauer, Piet Stinissen, Niels Hellings, Sanne G. S. Verberk, Gijs Kooij, Martin Giera, Johannes V. Swinnen, Bieke Broux, Markus Kleinewietfeld, Jerome J. A. Hendriks, Jeroen F. J. Bogie
Publikováno v:
Cellular and Molecular Immunology, 20(6), 666-679. Nature Publishing Group
Grajchen, E, Loix, M, Baeten, P, Côrte-Real, B F, Hamad, I, Vanherle, S, Haidar, M, Dehairs, J, Broos, J Y, Ntambi, J M, Zimmermann, R, Breinbauer, R, Stinissen, P, Hellings, N, Verberk, S G S, Kooij, G, Giera, M, Swinnen, J V, Broux, B, Kleinewietfeld, M, Hendriks, J J A & Bogie, J F J 2023, ' Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity ', Cellular and Molecular Immunology, vol. 20, no. 6, pp. 666-679 . https://doi.org/10.1038/s41423-023-01011-2
Grajchen, E, Loix, M, Baeten, P, Côrte-Real, B F, Hamad, I, Vanherle, S, Haidar, M, Dehairs, J, Broos, J Y, Ntambi, J M, Zimmermann, R, Breinbauer, R, Stinissen, P, Hellings, N, Verberk, S G S, Kooij, G, Giera, M, Swinnen, J V, Broux, B, Kleinewietfeld, M, Hendriks, J J A & Bogie, J F J 2023, ' Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity ', Cellular and Molecular Immunology, vol. 20, no. 6, pp. 666-679 . https://doi.org/10.1038/s41423-023-01011-2
The imbalance between pathogenic and protective T cell subsets is a cardinal feature of autoimmune disorders such as multiple sclerosis (MS). Emerging evidence indicates that endogenous and dietary-induced changes in fatty acid metabolism have a majo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0453077196c63a160f7fb022361b2740
https://cris.maastrichtuniversity.nl/en/publications/91c2f0c1-489d-4001-92ff-b59bf00eacea
https://cris.maastrichtuniversity.nl/en/publications/91c2f0c1-489d-4001-92ff-b59bf00eacea
Autor:
Judith C. Sluimer, Michel van Weeghel, Helga E. de Vries, Sanne G.S. Verberk, Soufyan Lakbir, Koen H.M. Prange, Marion J.J. Gijbels, Gijs Kooij, Saskia van der Velden, Menno P.J. de Winther, Cindy P. P. A. van Roomen, Guillermo R. Griffith, Douwe Molenaar, Jan Van den Bossche, Jelle Y. Broos, Elisa Meinster, Esther Lutgens, Jeroen Baardman, Annette E. Neele, Kathryn E. Wellen
Publikováno v:
Baardman, J, Verberk, S G S, van der Velden, S, Gijbels, M J J, van Roomen, C P P A, Sluimer, J C, Broos, J Y, Griffith, G R, Prange, K H M, van Weeghel, M, Lakbir, S, Molenaar, D, Meinster, E, Neele, A E, Kooij, G, de Vries, H E, Lutgens, E, Wellen, K E, de Winther, M P J & Van den Bossche, J 2020, ' Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques ', Nature Communications, vol. 11, no. 1, 6296 . https://doi.org/10.1038/s41467-020-20141-z
Nature Communications
Nature Communications, 11(1):6296. Nature Publishing Group UK
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications, 11(1):6296. Nature Publishing Group
Nature communications, 11(1):6296. Nature Publishing Group
Nature Communications
Nature Communications, 11(1):6296. Nature Publishing Group UK
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications, 11(1):6296. Nature Publishing Group
Nature communications, 11(1):6296. Nature Publishing Group
Macrophages represent a major immune cell population in atherosclerotic plaques and play central role in the progression of this lipid-driven chronic inflammatory disease. Targeting immunometabolism is proposed as a strategy to revert aberrant macrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d624db238132ccb5970a8f084c666343
https://doi.org/10.1038/s41467-020-20141-z
https://doi.org/10.1038/s41467-020-20141-z
Autor:
Slimmen, Lisa JM1,2 (AUTHOR), Broos, Jelle Y3,4 (AUTHOR), Manaï, Badies HAN1 (AUTHOR), Estevão, Silvia C2 (AUTHOR), Giera, Martin4 (AUTHOR), Kooij, Gijs3 (AUTHOR), Unger, Wendy WJ2 (AUTHOR), Janssens, Hettie M1 (AUTHOR) h.janssens@erasmusmc.nl
Publikováno v:
Clinical & Translational Immunology. Sep2024, Vol. 13 Issue 9, p1-12. 12p.
Autor:
Broos, Jelle Y.1,2,3 (AUTHOR), van der Burgt, Rianne T. M.1,2 (AUTHOR), Konings, Julia1,2,4,5 (AUTHOR), Rijnsburger, Merel1,2,4,6 (AUTHOR), Werz, Oliver7 (AUTHOR), de Vries, Helga E.1,4 (AUTHOR), Giera, Martin3 (AUTHOR), Kooij, Gijs1,2,4,5 (AUTHOR) g.kooij@amsterdamumc.nl
Publikováno v:
Journal of Neuroinflammation. 1/17/2024, Vol. 21 Issue 1, p1-20. 20p.
Publikováno v:
Multiple Sclerosis Journal; Oct2022 Suppl 3, Vol. 28, p130-691, 562p
Publikováno v:
Respiratory Therapeutics Week; 10/18/2024, p872-872, 1p