Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jelle L. Vosters"'
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51375 (2012)
CD40-CD154 (CD40 ligand) interaction in the co-stimulatory pathway is involved in many (auto)immune processes and both molecules are upregulated in salivary glands of Sjögren's syndrome (SS) patients. Interference within the CD40 pathway has amelior
Externí odkaz:
https://doaj.org/article/af38082c2d02445080fe10e5c6f1312e
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19962 (2011)
Intercellular adhesion molecule-1 (ICAM-1) is involved in migration and co-stimulation of T and B cells. Membrane bound ICAM-1 is over expressed in the salivary glands (SG) of Sjögren's syndrome (SS) patients and has therefore been proposed as a pot
Externí odkaz:
https://doaj.org/article/e7e94273db88427781e2ce01653f7fed
Autor:
Hongen Yin, Jelle L Vosters, Nienke Roescher, Anil D'Souza, Biji T Kurien, Paul P Tak, John A Chiorini
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18003 (2011)
INTRODUCTION: Anti-Ro antibodies can be found in the serum of the majority of patients with Sjögren's syndrome (SS). Immunization with a 60-kDa Ro peptide has been shown to induce SS-like symptoms in mice. The aim of this study was to investigate fa
Externí odkaz:
https://doaj.org/article/69ba32f632aa41c49dcee4295d2d2816
Autor:
PP Tak, Patrick A. Dreyfus, Sébastien Jacques, Gilles Chiocchia, Jelle L. Vosters, Nienke Roescher, John A. Chiorini, Jean Sibilia, Ghada Alsaleh, Xavier Mariette, Jacques-Eric Gottenberg
Publikováno v:
Molecular therapy, 22(4), 821-827. Nature Publishing Group
BAFF (B-cell–activating factor of the tumor necrosis factor family), a pivotal cytokine for B-cell activation, is overexpressed by salivary gland (SG) epithelial cells in primary Sjogren's syndrome (pSS). ΔBAFF, a physiological inhibitor of BAFF,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c57c8c22ee54633c09bd9e1b8a847b5
Publikováno v:
Rheumatology (Oxford, England), 51(9), 1557-1562. Oxford University Press
Objective. A proliferation-inducing ligand (APRIL) and B-cell activating factor (BAFF) are B-cell-related mediators and may play a role in the pathogenesis in SS. In this descriptive study we assessed the expression of APRIL and BAFF in the minor sal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d782f35cecebfd2c28c8d07c9972effb
https://doi.org/10.1093/rheumatology/kes080
https://doi.org/10.1093/rheumatology/kes080
Publikováno v:
Oral Diseases. 18:365-374
Objective Sjogren’s syndrome (SS) patients show aberrant expression of the B cell-related mediators B cell activating factor (BAFF) and a proliferation-inducing ligand (APRIL) in serum and salivary glands (SGs). We studied the biological effect of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6a8fe5ec13bb8c082d3f82be02e4d55
https://doi.org/10.1111/j.1601-0825.2011.01885.x
https://doi.org/10.1111/j.1601-0825.2011.01885.x
Autor:
BM Lodde, Paul P. Tak, Jelle L. Vosters, Gabor G. Illei, Nienke Roescher, Marcelo A. Catalán, John A. Chiorini
Publikováno v:
Oral Diseases. 18:96-106
Oral Diseases (2011) 18, 96–106 Objective: Non-obese diabetic (NOD) mice develop an autoimmune exocrinopathy that shows similarities with Sjogren’s syndrome. They provide an experimental model to study the pathoetiogenesis of this disease. Materi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c36712818895d5353655ee07e2b0e57d
https://doi.org/10.1111/j.1601-0825.2011.01852.x
https://doi.org/10.1111/j.1601-0825.2011.01852.x
Autor:
John A. Chiorini, Paul P. Tak, William D. Swaim, Patrizio Caturegli, Melissa A. Landek-Salgado, Hiroaki Kimura, Hongen Yin, Jelle L. Vosters
Publikováno v:
Arthritis and rheumatism, 60(12), 3633-3641. John Wiley and Sons Inc.
Objective Interleukin-12 (IL-12) is a pleiotropic cytokine that is elevated in the affected organs of patients with Sjogren's syndrome (SS). We have previously reported that overexpression of IL-12 in CBA mice leads to mononuclear infiltration of sal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e22cf918966ff193024458351759464
https://doi.org/10.1002/art.24980
https://doi.org/10.1002/art.24980
Autor:
Niels Broekstra, F. A. Koopman, Margriet J. Vervoordeldonk, Jelle L. Vosters, Paul P. Tak, Nienke Roescher
Publikováno v:
Oral diseases, 21(7), 858-865. Wiley-Blackwell
Objective Activation of the cholinergic anti-inflammatory pathway (CAP) has been shown to reduce inflammation in animal models, while abrogation of the pathway increases inflammation. We investigated whether modulation of CAP influences inflammation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3bf9a519ad57201be93520f3d633b6
https://pubmed.ncbi.nlm.nih.gov/26096224
https://pubmed.ncbi.nlm.nih.gov/26096224
Publikováno v:
Future Rheumatology. 1:433-440
Sjogren’s syndrome (SS) is a complex autoimmune disorder characterized by mononuclear infiltration of the exocrine glands. There is an increased interest to use immunomodulatory protein therapy to target inflammatory components thought to be import
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c94f373e7ec490bcf66a5b181cd4a629
https://doi.org/10.2217/17460816.1.4.433
https://doi.org/10.2217/17460816.1.4.433