Výsledky vyhledávání - "Jelle Jacobs"

Akademický článek

dachshund Potentiates Hedgehog Signaling during Drosophila Retinogenesis.

Autor: Catarina Brás-Pereira, Delphine Potier, Jelle Jacobs, Stein Aerts, Fernando Casares, Florence Janody

Publikováno v: PLoS Genetics, Vol 12, Iss 7, p e1006204 (2016)

Proper organ patterning depends on a tight coordination between cell proliferation and differentiation. The patterning of Drosophila retina occurs both very fast and with high precision. This process is driven by the dynamic changes in signaling acti

Externí odkaz: https://doaj.org/article/5635e6f747d2444d9b2fe8d2e38f8b40

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Akademický článek

Discovery of transcription factors and regulatory regions driving in vivo tumor development by ATAC-seq and FAIRE-seq open chromatin profiling.

Autor: Kristofer Davie, Jelle Jacobs, Mardelle Atkins, Delphine Potier, Valerie Christiaens, Georg Halder, Stein Aerts

Publikováno v: PLoS Genetics, Vol 11, Iss 2, p e1004994 (2015)

Genomic enhancers regulate spatio-temporal gene expression by recruiting specific combinations of transcription factors (TFs). When TFs are bound to active regulatory regions, they displace canonical nucleosomes, making these regions biochemically de

Externí odkaz: https://doaj.org/article/06c04a5555414c05a03f1378b8b54139

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Robust stability analysis of an energy-efficient control in a Networked Control System with application to unmanned ground vehicles

Autor: Ángel Cuenca, Jelle Jacobs, Antonio González, Julián Salt

Publikováno v: Information Sciences. 578:64-84

In this paper, the robust stability and disturbance rejection performance analysis of an energy-efficient control is addressed in the framework of Networked Control System (NCS). The control scheme under study integrates periodic event-triggered cont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0bf0bccce3f0eb50bbf629e0c799d8c2
https://doi.org/10.1016/j.ins.2021.07.016

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Widespread regulatory specificities between transcriptional corepressors and enhancers inDrosophila

Autor: Jelle Jacobs, Michaela Pagani, Christoph Wenzl, Alexander Stark

Animal development and homeostasis critically depend on the accurate regulation of gene transcription, which includes the silencing of genes that should not be expressed. Repression is mediated by a specific class of transcription factors (TFs) terme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85cc67183f3f57f865fe982433840497
https://doi.org/10.1101/2022.11.07.515017

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Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice

Publikováno v: Science

Mixed signals at tumor margins The Hippo signaling pathway has been implicated in tumor growth, sparking interest in the pathway as a potential therapeutic target. In a study of liver cancer in genetically manipulated mice, Moya et al. discovered tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234c109f36b57c4eab816f97aa40c901
https://hdl.handle.net/20.500.14017/03a10daa-4bf0-482c-8c9d-9b1ef20770f8

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An Ectopic Network of Transcription Factors Regulated by Hippo Signaling Drives Growth and Invasion of a Malignant Tumor Model

Autor: Lucia Romanelli, Jelle Jacobs, Jana Mach, Mardelle Atkins, Delphine Potier, Georg Halder, Stein Aerts, Fisun Hamaratoglu

Publikováno v: Current Biology

Cancer cells have abnormal gene expression profiles; however, to what degree these are chaotic or driven by structured gene regulatory networks is often not known. Here we studied a model of Ras-driven invasive tumorigenesis in Drosophila epithelial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85c1c598a7036031a17e5ca88cc3305e

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The transcription factor Grainy head primes epithelial enhancers for spatiotemporal activation by displacing nucleosomes

Autor: Jasper Wouters, Giulia Paciello, Sara Aibar, Mardelle Atkins, Gert Hulselmans, Delphine Potier, Valerie Christiaens, Hana Imrichova, Georg Halder, Duygu Koldere, Kristofer Davie, Lucia Romanelli, Ibrahim Ihsan Taskiran, Stein Aerts, Carmen Bravo González-Blas, Jelle Jacobs

Publikováno v: Nature Genetics
Nature Genetics, Nature Publishing Group, In press, 50 (7), pp.1011-1020. ⟨10.1038/s41588-018-0140-x⟩
Nature genetics

Transcriptional enhancers function as docking platforms for combinations of transcription factors (TFs) to control gene expression. How enhancer sequences determine nucleosome occupancy, TF recruitment and transcriptional activation in vivo remains u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3187b99aae7cb5d3e772ad2c6f86e61
https://hal.archives-ouvertes.fr/hal-03392207

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Hippo Reprograms the Transcriptional Response to Ras Signaling

Autor: Malini Natarajan, Fisun Hamaratoglu, Leticia Sansores-Garcia, Julia Zeitlinger, Georg Halder, Justine Pascual, Stein Aerts, Jelle Jacobs

Publikováno v: Developmental cell. 42(6)

Hyperactivating mutations in Ras signaling are hallmarks of carcinomas. Ras signaling mediates cell fate decisions as well as proliferation during development. It is not known what dictates whether Ras signaling drives differentiation versus prolifer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa085b72014bb0cdaa2917cf5a9016a
https://pubmed.ncbi.nlm.nih.gov/28950097

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dachshund Potentiates Hedgehog Signaling during Drosophila Retinogenesis

Autor: Delphine Potier, Fernando Casares, Catarina Brás-Pereira, Jelle Jacobs, Stein Aerts, Florence Janody

Publikováno v: PLoS Genetics, Vol 12, Iss 7, p e1006204 (2016)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
PLoS Genetics
PLoS Genetics, Public Library of Science, 2016, 12 (7), pp.e1006204. ⟨10.1371/journal.pgen.1006204⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd0f864bf7ee9ece87b0e036b55bfcbc
http://europepmc.org/articles/PMC4956209?pdf=render

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