Zobrazeno 1 - 10
of 216
pro vyhledávání: '"Jelle J Goeman"'
Autor:
Maria Fiorella Contarino, Ed J Kuijper, Andrea E van der Meulen-de Jong, Josbert J Keller, Jacobus J van Hilten, Jelle J Goeman, Hein W Verspaget, Karuna EW Vendrik, Vlada O Chernova, Elisabeth M Terveer, Joffrey van Prehn, Eric KL Berssenbrugge, Jannie GE Henderickx, Martijn P Bauer, Romy D Zwittink
Publikováno v:
BMJ Open, Vol 13, Iss 10 (2023)
Introduction Experimental studies suggest a role of gut microbiota in the pathophysiology of Parkinson’s disease (PD) via the gut–brain axis. The gut microbiota can also influence the metabolism of levodopa, which is the mainstay of treatment of
Externí odkaz:
https://doaj.org/article/a1f26c1154924ebd886a4fa9d984ae94
Autor:
Monika Hiller, Maria Sofia Falzarano, Iker Garcia-Jimenez, Valentina Sardone, Ruurd C Verheul, Linda Popplewell, Karen Anthony, Estibaliz Ruiz-Del-Yerro, Hana Osman, Jelle J Goeman, Kamel Mamchaoui, George Dickson, Alessandra Ferlini, Francesco Muntoni, Annemieke Aartsma-Rus, Virginia Arechavala-Gomeza, Nicole A Datson, Pietro Spitali
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204485 (2018)
BACKGROUND:Duchenne muscular dystrophy is a lethal disease caused by lack of dystrophin. Skipping of exons adjacent to out-of-frame deletions has proven to restore dystrophin expression in Duchenne patients. Exon 51 has been the most studied target i
Externí odkaz:
https://doaj.org/article/bfcda443e99b4e5388c172844550fbbe
Autor:
Roberta Rovito, Hans-Jörg Warnatz, Szymon M Kiełbasa, Hailiang Mei, Vyacheslav Amstislavskiy, Ramon Arens, Marie-Laure Yaspo, Hans Lehrach, Aloys C M Kroes, Jelle J Goeman, Ann C T M Vossen
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200652 (2018)
Congenital Cytomegalovirus infection (cCMV) is the leading infection in determining permanent long-term impairments (LTI), and its pathogenesis is largely unknown due to the complex interplay between viral, maternal, placental, and child factors. The
Externí odkaz:
https://doaj.org/article/d0aec4e74df94aa6afe02fab2c3e2ce1
Autor:
Krista E van Meijgaarden, Bhagwati Khatri, Steven G Smith, Anne M F H Drittij, Roelof A de Paus, Jelle J Goeman, Mei M Ho, Hazel M Dockrell, Helen McShane, Simone A Joosten, Tom H M Ottenhoff
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0201205 (2018)
BACKGROUND:Multiplex assays are increasingly applied to analyze multicomponent signatures of human immune responses, including the dynamics of cytokine and chemokine production, in observational as well as interventional studies following treatment o
Externí odkaz:
https://doaj.org/article/280d6518eb2f41ccb8c6ae2de8437623
Autor:
Hans Timmerman, Monique A H Steegers, Frank J P M Huygen, Jelle J Goeman, Nick T van Dasselaar, Marcel J Schenkels, Oliver H G Wilder-Smith, André P Wolff, Kris C P Vissers
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187961 (2017)
Neuropathic pain is clinically described as pain caused by a lesion or disease of the somatosensory nervous system. The aim of this study was to assess the validity of the Dutch version of the DN4, in a cross-sectional multicentre design, as a screen
Externí odkaz:
https://doaj.org/article/0a0d3e9f529c488a82745069626f57d5
Autor:
Yolande F M Ramos, Wouter den Hollander, Judith V M G Bovée, Nils Bomer, Ruud van der Breggen, Nico Lakenberg, J Christiaan Keurentjes, Jelle J Goeman, P Eline Slagboom, Rob G H H Nelissen, Steffan D Bos, Ingrid Meulenbelt
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103056 (2014)
ObjectiveIdentify gene expression profiles associated with OA processes in articular cartilage and determine pathways changing during the disease process.MethodsGenome wide gene expression was determined in paired samples of OA affected and preserved
Externí odkaz:
https://doaj.org/article/2fa3036c8c66493fa4581fdf30a306d5
Autor:
Chris Lauber, Jelle J Goeman, Maria del Carmen Parquet, Phan Thi Nga, Eric J Snijder, Kouichi Morita, Alexander E Gorbalenya
Publikováno v:
PLoS Pathogens, Vol 9, Iss 7, p e1003500 (2013)
The small size of RNA virus genomes (2-to-32 kb) has been attributed to high mutation rates during replication, which is thought to lack proof-reading. This paradigm is being revisited owing to the discovery of a 3'-to-5' exoribonuclease (ExoN) in ni
Externí odkaz:
https://doaj.org/article/ffe37aa6492648b288f00d6c33ddf777
Autor:
Sabrina A H M van den Tillaart, Wim E Corver, Dina Ruano Neto, Natalja T ter Haar, Jelle J Goeman, J Baptist M Z Trimbos, Gertjan J Fleuren, Jan Oosting
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67414 (2013)
Treatment choices for cervical cancer are primarily based on clinical FIGO stage and the post-operative evaluation of prognostic parameters including tumor diameter, parametrial and lymph node involvement, vaso-invasion, infiltration depth, and histo
Externí odkaz:
https://doaj.org/article/dbbf850262d44f48a705f1b69c2b443e
Autor:
Sandy A van Gool, Joyce A M Emons, Jeroen C H Leijten, Eva Decker, Carsten Sticht, Johannes C van Houwelingen, Jelle J Goeman, Carin Kleijburg, Sicco A Scherjon, Norbert Gretz, Jan Maarten Wit, Gudrun Rappold, Janine N Post, Marcel Karperien
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e44561 (2012)
We used human fetal bone marrow-derived mesenchymal stromal cells (hfMSCs) differentiating towards chondrocytes as an alternative model for the human growth plate (GP). Our aims were to study gene expression patterns associated with chondrogenic diff
Externí odkaz:
https://doaj.org/article/0d7f3ea473844d028838b15a55294cfd
Autor:
Willemijn M Passtoors, Judith M Boer, Jelle J Goeman, Erik B van den Akker, Joris Deelen, Bas J Zwaan, Ann Scarborough, Ruud van der Breggen, Rolf H A M Vossen, Jeanine J Houwing-Duistermaat, Gert Jan B van Ommen, Rudi G J Westendorp, Diana van Heemst, Anton J M de Craen, Andrew J White, David A Gunn, Marian Beekman, P Eline Slagboom
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e27759 (2012)
The Leiden Longevity Study consists of families that express extended survival across generations, decreased morbidity in middle-age, and beneficial metabolic profiles. To identify which pathways drive this complex phenotype of familial longevity and
Externí odkaz:
https://doaj.org/article/626bb1fceb39466c9dd77168f560b53b