Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jelle, Offringa"'
Autor:
Daan van der Es, Adriaan P. IJzerman, Jelle Offringa, Xue Yang, Laura H. Heitman, Eelke B. Lenselink, Jacobus P. D. van Veldhoven, Boaz J. Kuiper
Publikováno v:
Journal of Medicinal Chemistry, 62(7), 3539-3552
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry
The development of covalent ligands for G protein-coupled receptors (GPCRs) is not a trivial process. Here, we report a streamlined workflow thereto from synthesis to validation, exemplified by the discovery of a covalent antagonist for the human ade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bf14842a65be649f77157c82babf912
http://hdl.handle.net/1887/80320
http://hdl.handle.net/1887/80320
Autor:
Xue, Yang, Jacobus P D, van Veldhoven, Jelle, Offringa, Boaz J, Kuiper, Eelke B, Lenselink, Laura H, Heitman, Daan, van der Es, Adriaan P, IJzerman
Publikováno v:
Journal of medicinal chemistry. 62(7)
[Image: see text] The development of covalent ligands for G protein-coupled receptors (GPCRs) is not a trivial process. Here, we report a streamlined workflow thereto from synthesis to validation, exemplified by the discovery of a covalent antagonist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::677d03a95880ad55ad931a5b73945fbd
https://pubmed.ncbi.nlm.nih.gov/30869893
https://pubmed.ncbi.nlm.nih.gov/30869893
