Anti-parasitic dinuclear thiolato-bridged arene ruthenium complexes alter the mitochondrial ultrastructure and membrane potential in Trypanosoma brucei bloodstream forms

Autor: Jelk, Jennifer, Balmer, Vreni, Stibal, David, Giannini, Federico, Süss-Fink, Georg, Bütikofer, Peter, Furrer, Julien, Hemphill, Andrew

Publikováno v: In Experimental Parasitology October 2019 205

Cellular and Molecular Targets of Nucleotide-Tagged Trithiolato-Bridged Arene Ruthenium Complexes in the Protozoan Parasites Toxoplasma gondii and Trypanosoma brucei

Autor: Anghel, Nicoleta, Müller, Joachim, Serricchio, Mauro, Jelk, Jennifer, Bütikofer, Peter, Boubaker, Ghalia, Imhof, Dennis, Ramseier, Jessica, Desiatkina, Oksana, Paunescu, Emilia, Braga, Sophie Marie-Pierre, Heller, Manfred, Furrer, Julien, Hemphill, Andrew

Publikováno v: Anghel, Nicoleta; Müller, Joachim; Serricchio, Mauro; Jelk, Jennifer; Bütikofer, Peter; Boubaker, Ghalia; Imhof, Dennis; Ramseier, Jessica; Desiatkina, Oksana; Paunescu, Emilia; Braga, Sophie Marie-Pierre; Heller, Manfred; Furrer, Julien; Hemphill, Andrew (2021). Cellular and Molecular Targets of Nucleotide-Tagged Trithiolato-Bridged Arene Ruthenium Complexes in the Protozoan Parasites Toxoplasma gondii and Trypanosoma brucei. International journal of molecular sciences, 22(19) Molecular Diversity Preservation International MDPI 10.3390/ijms221910787
International Journal of Molecular Sciences, Vol 22, Iss 10787, p 10787 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 19

Toxoplasma gondii is an apicomplexan parasite that infects and proliferates within many different types of host cells and infects virtually all warm-blooded animals and humans. Trypanosoma brucei is an extracellular kinetoplastid that causes human Af

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e6b46d2fd00b2340a3485cf9c52ff28
https://boris.unibe.ch/160247/1/Anghel_et_al_ijms-22-10787-v2.pdf

Phosphatidylethanolamine in Trypanosoma brucei Is Organized in Two Separate Pools and Is Synthesized Exclusively by the Kennedy Pathway

Autor: Signorell, Aita, Rauch, Monika, Jelk, Jennifer, Ferguson, Michael A.J., Bütikofer, Peter

Publikováno v: In Journal of Biological Chemistry 29 August 2008 283(35):23636-23644

Lipoprotein aggregation protects human monocyte-derived macrophages from OxLDL-induced cytotoxicity

Autor: Asmis, Reto ^*, Begley, Jim G. ^*, Jelk, Jennifer ^*, Everson, William V.

Publikováno v: In Journal of Lipid Research June 2005 46(6):1124-1132

TbLpn, a key enzyme in lipid droplet formation and phospholipid metabolism, is essential for mitochondrial integrity and growth of Trypanosoma brucei

Autor: Dawoody Nejad, Ladan, Serricchio, Mauro, Jelk, Jennifer, Hemphill, Andrew, Bütikofer, Peter

Mammalian phosphatidic acid phosphatases, also called lipins, show high amino acid sequence identity to Saccharomyces cerevisiae Pah1p and catalyze the dephosphorylation of phosphatidic acid (PA) to diacylglycerol. Both the substrate and product of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b510bda848b0e7c7ecfa6ac39ef528c2