The potential roles of gossypol as anticancer agent: advances and future directions

Autor: Danijela Paunovic, Jovana Rajkovic, Radmila Novakovic, Jelica Grujic-Milanovic, Reham Hassan Mekky, Dragos Popa, Daniela Calina, Javad Sharifi-Rad

Publikováno v: Chinese Medicine, Vol 18, Iss 1, Pp 1-17 (2023)

Abstract Gossypol, a polyphenolic aldehyde derived from cottonseed plants, has seen a transformation in its pharmaceutical application from a male contraceptive to a candidate for cancer therapy. This shift is supported by its recognized antitumor pr

Externí odkaz: https://doaj.org/article/a47b6226143b43679abc2bacdd762381

Characterization of dried chokeberry fruit extract and its chronic effects on blood pressure and oxidative stress in spontaneously hypertensive rats

Autor: Nada Ćujić, Katarina Savikin, Zoran Miloradovic, Milan Ivanov, Una-Jovana Vajic, Danijela Karanovic, Jelica Grujic-Milanovic, Djurdjica Jovovic, Nevena Mihailovic-Stanojevic

Publikováno v: Journal of Functional Foods, Vol 44, Iss , Pp 330-339 (2018)

The potential beneficial effects of chronic consumption of dried chokeberry fruit extract (DCE) were evaluated in the present in vivo study. The study concentrates on haemodynamic parameters, lipid profile and oxidative stress in spontaneously hypert

Externí odkaz: https://doaj.org/article/e327ccc14168498ba8d5f31a6f2ac1cf

Moderate consumption of alcohol-free red wine provide more beneficial effects on systemic haemodynamics, lipid profile and oxidative stress in spontaneously hypertensive rats than red wine

Autor: Nevena Mihailovic-Stanojevic, Katarina Savikin, Jelena Zivkovic, Gordana Zdunic, Zoran Miloradovic, Milan Ivanov, Danijela Karanovic, Una-Jovana Vajic, Djurdjica Jovovic, Jelica Grujic-Milanovic

Publikováno v: Journal of Functional Foods, Vol 26, Iss , Pp 719-730 (2016)

Numerous studies have shown that moderate wine consumption is associated with decreased incidence of cardiovascular disease, including hypertension. Others observed that moderate alcohol consumption lowers the risk of cardiovascular events. The aim o

Externí odkaz: https://doaj.org/article/1554309b0e4d49f3912db891abd3004e

Resveratrol Protects Cardiac Tissue in Experimental Malignant Hypertension Due to Antioxidant, Anti-Inflammatory, and Anti-Apoptotic Properties

Autor: Jelica Grujic-Milanovic, Ivica Milosavljevic, Djurdjica Jovovic, Vesna Jaćević, Nevena Mihailovic-Stanojevic, Sladjan Milanovic, Zoran Miloradovic

Publikováno v: International Journal of Molecular Sciences; Volume 22; Issue 9; Pages: 5006
International Journal of Molecular Sciences, Vol 22, Iss 5006, p 5006 (2021)
International Journal of Molecular Sciences

Hypertension is one of the most prevalent and powerful contributors of cardiovascular diseases. Malignant hypertension is a relatively rare but extremely severe form of hypertension accompanied with heart, brain, and renal impairment. Resveratrol, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50a04809e2f8b5192a68e8cfdb2ff863

DNA, protein and lipid oxidative damage in tissues of spontaneously hypertensive versus normotensive rats

Autor: Nevena Mihailovic-Stanojevic, Jelica Grujic-Milanovic, Djurdjica Jovovic, Biljana Spremo-Potparević, Marija Bruic, Lada Zivkovic, Danijela Karanovic, Zoran Miloradovic

Publikováno v: International Journal of Biochemistry and Cell Biology
The International Journal of Biochemistry & Cell Biology

Oxidative damage to protein and lipid macromolecules in target organs in hypertension has been recognized as a major factor contributing to cardiovascular, cerebrovascular, and renal diseases. Data on protein and lipid oxidative damage in spontaneous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdbf5cc57a4a8bba66c27fa104eb734d
https://farfar.pharmacy.bg.ac.rs/handle/123456789/3981