Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jelena Scekic-Zahirovic"'
Autor:
Jelena Scekic-Zahirovic, Inmaculada Sanjuan-Ruiz, Vanessa Kan, Salim Megat, Pierre De Rossi, Stéphane Dieterlé, Raphaelle Cassel, Marguerite Jamet, Pascal Kessler, Diana Wiesner, Laura Tzeplaeff, Valérie Demais, Sonu Sahadevan, Katharina M. Hembach, Hans-Peter Muller, Gina Picchiarelli, Nibha Mishra, Stefano Antonucci, Sylvie Dirrig-Grosch, Jan Kassubek, Volker Rasche, Albert Ludolph, Anne-Laurence Boutillier, Francesco Roselli, Magdalini Polymenidou, Clotilde Lagier-Tourenne, Sabine Liebscher, Luc Dupuis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Mutations in the RNA binding protein FUS are associated with ALS. Here the authors show that in FUS knock-in mice there is a progressive increase in neuronal activity in the frontal cortex which is associated with altered synaptic gene expression.
Externí odkaz:
https://doaj.org/article/81d53965ba1c4f5cbe4fa11bc13113fd
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that affects selected cortical and spinal neuronal populations, leading to progressive paralysis and death. A growing body of evidences suggests that the disease may origi
Externí odkaz:
https://doaj.org/article/8a1ed8a5b50042f1995609ace847b0c7
Publikováno v:
Brain Sciences, Vol 11, Iss 3, p 369 (2021)
Amyotrophic lateral sclerosis (ALS) is a devastating and fatal neurodegenerative disease arising from the combined degeneration of upper motor neurons (UMN) in the motor cortex, and lower motor neurons (LMN) in the brainstem and spinal cord. This dua
Externí odkaz:
https://doaj.org/article/93db53e0b6864c3fbde7d3d58396af1b
Autor:
Sung Min Han, Hajer El Oussini, Jelena Scekic-Zahirovic, Jack Vibbert, Pauline Cottee, Jeevan K Prasain, Hugo J Bellen, Luc Dupuis, Michael A Miller
Publikováno v:
PLoS Genetics, Vol 9, Iss 9, p e1003738 (2013)
Mutations in VAPB/ALS8 are associated with amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA), two motor neuron diseases that often include alterations in energy metabolism. We have shown that C. elegans and Drosophila neurons secr
Externí odkaz:
https://doaj.org/article/0bb41b9fa1984e32b1e5534b1076581f
Autor:
Matei Bolborea, Pauline Vercruysse, Tselmen Daria, Johanna C. Reiners, Najwa Ouali Alami, Simon J. Guillot, Stéphane Dieterlé, Jérôme Sinniger, Jelena Scekic-Zahirovic, Amela Londo, Hippolyte Arcay, Marc-Antoine Goy, Claudia Nelson de Tapia, Dietmar R. Thal, Kazumoto Shibuya, Ryo Otani, Kimihito Arai, Satoshi Kuwabara, Albert C. Ludolph, Francesco Roselli, Deniz Yilmazer-Hanke, Luc Dupuis
Publikováno v:
Acta neuropathologica 145(6), 773-791 (2023). doi:10.1007/s00401-023-02569-x
Amyotrophic lateral sclerosis (ALS) is associated with impaired energy metabolism, including weight loss and decreased appetite which are negatively correlated with survival. Neural mechanisms underlying metabolic impairment in ALS remain unknown. AL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f18d3d203fa3b8454fd5faf2f5793b7
https://lirias.kuleuven.be/handle/20.500.12942/719930
https://lirias.kuleuven.be/handle/20.500.12942/719930
Publikováno v:
Brain Sciences; Volume 11; Issue 3; Pages: 369
Amyotrophic lateral sclerosis (ALS) is a devastating and fatal neurodegenerative disease arising from the combined degeneration of upper motor neurons (UMN) in the motor cortex, and lower motor neurons (LMN) in the brainstem and spinal cord. This dua
Autor:
Jelena, Scekic-Zahirovic, Mathieu, Fischer, Geoffrey, Stuart-Lopez, Thibaut, Burg, Johan, Gilet, Sylvie, Dirrig-Grosch, Christine, Marques, Marie-Christine, Birling, Pascal, Kessler, Caroline, Rouaux
Publikováno v:
Progress in neurobiology. 200
Amyotrophic lateral sclerosis (ALS) arises from the combined degeneration of motor neurons (MN) and corticospinal neurons (CSN). Recent clinical and pathological studies suggest that ALS might start in the motor cortex and spread along the corticofug
Autor:
Thibaut Burg, Mathieu Fischer, Geoffrey Stuart-Lopez, Jelena Scekic-Zahirovic, Caroline Rouaux, Marie-Christine Birling, Pascal Kessler
While clinical evidence of combined degeneration of the bulbar and spinal motor neurons (MN) together with the corticospinal neurons (CSN) is required to diagnose Amyotrophic Lateral Sclerosis (ALS), preclinical studies have mostly concentrated on MN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5741b61951a43f25ccac06df44b66983
https://doi.org/10.1101/2020.01.09.900944
https://doi.org/10.1101/2020.01.09.900944
Publikováno v:
Annals of Neurology
Autor:
Thibaut, Burg, Charlotte, Bichara, Jelena, Scekic-Zahirovic, Mathieu, Fischer, Geoffrey, Stuart-Lopez, Aurore, Brunet, François, Lefebvre, Matilde, Cordero-Erausquin, Caroline, Rouaux
Publikováno v:
Annals of neurology. 88(4)
Recent studies carried out on amyotrophic lateral sclerosis patients suggest that the disease might initiate in the motor cortex and spread to its targets along the corticofugal tracts. In this study, we aimed to test the corticofugal hypothesis of a