Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jelena Kezic"'
Autor:
Jelena Kezic, Paul G. McMenamin
Publikováno v:
Experimental eye research. 186
Previous studies have reported that topical exposure to the toll-like receptor (TLR) 9 ligand CpG-ODN causes widespread ocular inflammation, including retinal microglial activation and posterior segment inflammation. Here we sought to determine the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28868993af7ee2393d376742582d8eb2
https://pubmed.ncbi.nlm.nih.gov/31242444
https://pubmed.ncbi.nlm.nih.gov/31242444
Autor:
Mariapia A. Degli-Esposti, Peter Fleming, Kimmo Makinen, John V. Forrester, Christopher E. Andoniou, Matthew E. Wikstrom, Iona S. Schuster, Stephen R. Daley, Valentina Voigt, Jelena Kezic
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
Ocular antigens are sequestered behind the blood-retina barrier and the ocular environment protects ocular tissues from autoimmune attack. The signals required to activate autoreactive T cells and allow them to cause disease in the eye remain in part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c04c846c29ba106e6601a87a7b01e8
https://doi.org/10.1038/s41598-017-14618-z
https://doi.org/10.1038/s41598-017-14618-z
Publikováno v:
Neurobiology of Aging. 35:1722-1725
We have previously shown that the optic nerve of mice becomes increasingly vulnerable to injury with advancing age. Here, we investigated whether regular exercise can modify this age-related vulnerability and improve optic nerve recovery after injury
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bebde4617be9870163394df70cc76912
https://doi.org/10.1016/j.neurobiolaging.2014.01.019
https://doi.org/10.1016/j.neurobiolaging.2014.01.019
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 72:782-790
There has been considerable debate about whether dendritic cells (DCs), which are potent antigen-presenting cells pivotal to adaptive immune responses, are present in CNS parenchyma. In studies aimed at answering this issue, we discovered that while
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d7e964ac1bbf8620279e6e63daa1ad
https://doi.org/10.1097/nen.0b013e31829e8375
https://doi.org/10.1097/nen.0b013e31829e8375
Publikováno v:
Arthritis & Rheumatism. 64:762-771
OBJECTIVE—The spondyloarthropathies (such as ankylosing spondylitis) are multi-system inflammatory diseases that frequently result in uveitis, or intra-ocular eye inflammation. Despite the common co-occurrence of uveitis with arthritis, there has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::915bbfc3c7dec9a2a223f84037eed6ca
https://doi.org/10.1002/art.33404
https://doi.org/10.1002/art.33404
Publikováno v:
Investigative ophthalmologyvisual science. 56(5)
PURPOSE To induce chronic intraocular pressure (IOP) elevation in rat eyes by circumlimbal suture. METHODS Anesthetized (isoflurane) Long-Evans rats underwent unilateral circumlimbal suture implantation while the fellow eyes served as untreated contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7db6873b74eb6028c20153ae4a5d0e3
https://pubmed.ncbi.nlm.nih.gov/25829414
https://pubmed.ncbi.nlm.nih.gov/25829414
Publikováno v:
Experimental Eye Research. 83:1268-1280
The aim of the present study was to determine the capacity of resident corneal and limbal dendritic cells (DC) and macrophages to capture antigen (Ag) in vivo and compare this to their capacity in vitro to take up Ag during organ culture conditions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::108de9344d7d16134868dbd81c14125b
https://doi.org/10.1016/j.exer.2006.07.004
https://doi.org/10.1016/j.exer.2006.07.004
Publikováno v:
Clinical and Experimental Ophthalmology. 33:426-432
Anterior chamber-associated immune deviation (ACAID) is an animal model of tolerance induced experimentally by the injection of antigen into the anterior chamber of the eye. The unusual deviant immune response has both afferent and efferent arms and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::045db40f6b234903adf25a6259b00312
https://doi.org/10.1111/j.1442-9071.2005.01044.x
https://doi.org/10.1111/j.1442-9071.2005.01044.x
Autor:
Ian P. Wicks, Paul G. McMenamin, Gabrielle L. Goldberg, John V. Forrester, Xiangting Chen, Claude C.A. Bernard, Jelena Kezic
Publikováno v:
Journal of Neuroinflammation
Experimental autoimmune uveoretinitis (EAU) is a widely used experimental animal model of human endogenous posterior uveoretinitis. In the present study, we performed in vivo imaging of the retina in transgenic reporter mice to investigate dynamic ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3a83487853ac15cd1b4c07d18d12a69
https://doi.org/10.1186/s12974-015-0235-6
https://doi.org/10.1186/s12974-015-0235-6
Publikováno v:
Investigative ophthalmologyvisual science. 53(3)
PURPOSE The distribution, density, and phenotype of hyalocytes or vitreous macrophages in mouse eyes was examined during normal aging and in models of background diabetic retinopathy, retinal vascular proliferation, and exposure to TLR4 and TLR9 liga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::751610e9ca0cd87cbcdb3d12d8335668
https://pubmed.ncbi.nlm.nih.gov/22297487
https://pubmed.ncbi.nlm.nih.gov/22297487