Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Jelena, Skuljec"'
Autor:
Konstantin Fritz Jendretzky, Lisa-Marie Lezius, Thea Thiele, Franz Felix Konen, André Huss, Lena Heitmann, Yunus Emre Güzeloglu, Philipp Schwenkenbecher, Kurt-Wolfram Sühs, Jelena Skuljec, Mike Peter Wattjes, Torsten Witte, Christoph Kleinschnitz, Refik Pul, Hayrettin Tumani, Stefan Gingele, Thomas Skripuletz
Publikováno v:
Neurological Research and Practice, Vol 6, Iss 1, Pp 1-10 (2024)
Abstract Background Diagnosing multiple sclerosis (MS) is challenging due to diverse symptoms and the absence of specific biomarkers. Concurrent autoimmune diseases (AID) or non-specific antibodies further complicate diagnosis, progression monitoring
Externí odkaz:
https://doaj.org/article/8e185e916ca14246bf45240d22f85721
Autor:
Hans Georg Mannherz, Heidi Budde, Muhammad Jarkas, Roua Hassoun, Natalia Malek-Chudzik, Antonina J. Mazur, Jelena Skuljec, Refik Pul, Markus Napirei, Nazha Hamdani
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 2, Pp 151407- (2024)
We analyzed actin cytoskeleton alterations during NET extrusion by neutrophil-like dHL-60 cells and human neutrophils in the absence of DNase1 containing serum to avoid chromatin degradation and microfilament disassembly. NET-formation by dHL-60 cell
Externí odkaz:
https://doaj.org/article/54c354006106440fb8831ac2fa492eb0
Autor:
Stefan, Braune, Eleni, Karamasioti, Philip, van Hoevell, Arnfin, Bergmann, Jelena, Skuljec, Aksel, Siva, NTD Study Group, Refik, Pul
Publikováno v:
In Multiple Sclerosis and Related Disorders October 2024 90
Autor:
Markus Leo, Linda-Isabell Schmitt, Fabian Mairinger, Andreas Roos, Christina Hansmann, Stefanie Hezel, Jelena Skuljec, Refik Pul, Ulrike Schara-Schmidt, Christoph Kleinschnitz, Tim Hagenacker
Publikováno v:
Cells, Vol 12, Iss 19, p 2374 (2023)
5q-related Spinal muscular atrophy (SMA) is a hereditary multi-systemic disorder leading to progressive muscle atrophy and weakness caused by the degeneration of spinal motor neurons (MNs) in the ventral horn of the spinal cord. Three SMN-enhancing d
Externí odkaz:
https://doaj.org/article/f0c4e965a11049a49b14bcde21c3a753
Autor:
Leoni Rolfes, Steffen Pfeuffer, Jelena Skuljec, Xia He, Chuanxin Su, Sinem-Hilal Oezalp, Marc Pawlitzki, Tobias Ruck, Melanie Korsen, Konstanze Kleinschnitz, Derya Aslan, Tim Hagenacker, Christoph Kleinschnitz, Sven G. Meuth, Refik Pul
Publikováno v:
Cells, Vol 12, Iss 9, p 1243 (2023)
Cladribine has been approved for the treatment of multiple sclerosis (MS) and its administration results in a long-lasting depletion of lymphocytes. As lymphopenia is known to hamper immune responses to vaccination, we evaluated the immunogenicity of
Externí odkaz:
https://doaj.org/article/2c69ab7ca65a4bdfa251f6365b4ab19b
Autor:
Ana Milosevic, Irena Lavrnja, Danijela Savic, Katarina Milosevic, Jelena Skuljec, Ivana Bjelobaba, Marija M. Janjic
Publikováno v:
Cells, Vol 12, Iss 7, p 1045 (2023)
Multiple sclerosis (MS) is an autoimmune disease affecting the CNS and occurring far more prevalently in women than in men. In both MS and its animal models, sex hormones play important immunomodulatory roles. We have previously shown that experiment
Externí odkaz:
https://doaj.org/article/7d50de04757a45fd9f47a9ee8662b0c4
Autor:
Michael Fleischer, Helene Schuh, Nela M. Bickmann, Tim Hagenacker, Karlgeorg Krüger, Thomas Skripuletz, Melanie Fiedler, Christoph Kleinschnitz, Refik Pul, Jelena Skuljec
Publikováno v:
Neurologia i Neurochirurgia Polska. 56:236-245
Fatigue is the most frequent symptom in multiple sclerosis (MS), although it is still poorly understood due to its complexity and subjective nature. There is an urgent need to identify reliable biomarkers to improve disease prognosis and therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825cda7b5b2be724ad2c21a67a70939d
https://doi.org/10.5603/pjnns.a2022.0043
https://doi.org/10.5603/pjnns.a2022.0043
Autor:
Jelena Skuljec, Adan Chari Jirmo, Anika Habener, Steven R. Talbot, Refik Pul, Ruth Grychtol, Malik Aydin, Christoph Kleinschnitz, Christine Happle, Gesine Hansen
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Tissue macrophages are important components of tissue homeostasis and inflammatory pathologies. In the peritoneal cavity, resident macrophages interact with a variety of immune cells and can exhibit broad range of phenotypes and functions. Forkhead-b
Externí odkaz:
https://doaj.org/article/22fca28064b6464480e6aa578f9d9c1d
Autor:
Christoph Kleinschnitz, Jana Hackert, Anja Gäckler, Sven G. Meuth, Refik Pul, Helene Schuh, Tobias Ruck, Andreas Kribben, Kristina Schönfelder, Julia Krämer, Ute Eisenberger, Steffen Pfeuffer, Jelena Skuljec, Tim Hagenacker, Michael Fleischer, Frederick Pfister
Publikováno v:
Multiple Sclerosis (Houndmills, Basingstoke, England)
Background: Oral cladribine is an approved disease-modifying drug for the treatment of relapsing multiple sclerosis. In controlled clinical trials as well as in post marketing safety assessments, autoimmune conditions have not yet been reported as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d80d10bcfc829fdae792b8982fbb6f1a
https://doi.org/10.1177/13524585211022719
https://doi.org/10.1177/13524585211022719
Autor:
Jelena Skuljec, Markus Chmielewski, Christine Happle, Anika Habener, Mandy Busse, Hinrich Abken, Gesine Hansen
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Cellular therapy with chimeric antigen receptor (CAR)-redirected cytotoxic T cells has shown impressive efficacy in the treatment of hematologic malignancies. We explored a regulatory T cell (Treg)-based therapy in the treatment of allergic airway in
Externí odkaz:
https://doaj.org/article/bc91ba0d31094e63b8d304750bf7d2c2