Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jelena, Nedjic"'
Autor:
Maryknoll Palisoc, Sulei Xu, Jelena Nedjic, Natalia Shulzhenko, Changsik Shin, Richard R. Rodrigues, Sravya Kurapati, Indira Purushothaman, Iannis Aifantis, Eugene Lin, Sathi Babu Chodisetti, Zia Ur Rahman, Azree Zaffran Ashraf, Matthias Mack, Pingnian He, Balázs Koscsó, Chetna Soni, Kavitha Gowda, Yuka Imamura Kawasawa, Milena Bogunovic, Haoyu Sun, Andrey Morgun
Publikováno v:
Science Immunology. 5
Intestinal mononuclear phagocytes (MPs) are composed of heterogeneous dendritic cell (DC) and macrophage subsets necessary for the initiation of immune response and control of inflammation. Although MPs in the normal intestine have been extensively s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85f8e757b23fa92e1f7d50d362ec9f8a
https://doi.org/10.1126/sciimmunol.aax0062
https://doi.org/10.1126/sciimmunol.aax0062
Autor:
Balázs, Koscsó, Sravya, Kurapati, Richard R, Rodrigues, Jelena, Nedjic, Kavitha, Gowda, Changsik, Shin, Chetna, Soni, Azree Zaffran, Ashraf, Indira, Purushothaman, Maryknoll, Palisoc, Sulei, Xu, Haoyu, Sun, Sathi Babu, Chodisetti, Eugene, Lin, Matthias, Mack, Yuka Imamura, Kawasawa, Pingnian, He, Ziaur S M, Rahman, Iannis, Aifantis, Natalia, Shulzhenko, Andrey, Morgun, Milena, Bogunovic
Publikováno v:
Sci Immunol
Intestinal mononuclear phagocytes (MPs) are composed of heterogeneous dendritic cell (DC) and macrophage subsets necessary for the initiation of immune response and control of inflammation. Although MPs in the normal intestine have been extensively s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::40dca0f29bf9b032838f5a44e84ceb93
https://pubmed.ncbi.nlm.nih.gov/32276965
https://pubmed.ncbi.nlm.nih.gov/32276965
Autor:
Meinrad Busslinger, Esther Lutgens, Norbert Gerdes, Tomoyoshi Yamano, Jelena Nedjic, Benedikt Brors, Madlen Steinert, Maria Hinterberger, Sheena Pinto, Naozumi Ishimaru, Sandra D Koser, Bruno Kyewski, Ludger Klein
Publikováno v:
Immunity, 42(6), 1048-1061. Cell Press
Summary Thymic antigen-presenting cells (APCs) such as dendritic cells and medullary thymic epithelial cells (mTECs) use distinct strategies of self-antigen expression and presentation to mediate central tolerance. The thymus also harbors B cells; wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a56a3afa14eff3431ef68e94209df0
https://doi.org/10.1016/j.immuni.2015.05.013
https://doi.org/10.1016/j.immuni.2015.05.013
Autor:
Alexander Steinkasserer, Elisabetta Petrozziello, Jelena Nedjic, Christine Federle, Hidde L. Ploegh, Julia von Rohrscheidt, Satoshi Ishido, Lena Krzyzak, Ludger Klein
Publikováno v:
The Journal of Experimental Medicine
Rockefeller University Press
Rockefeller University Press
Work from the Klein lab shows that CD83 supports T cell selection in the thymus by restraining March8-mediated MHCII ubiquitination and internalization.
Deficiency of CD83 in thymic epithelial cells (TECs) dramatically impairs thymic CD4 T cell
Deficiency of CD83 in thymic epithelial cells (TECs) dramatically impairs thymic CD4 T cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65029e5a9f5466e1836879441908b3f8
https://pubmed.ncbi.nlm.nih.gov/27503071
https://pubmed.ncbi.nlm.nih.gov/27503071
Publikováno v:
Current Opinion in Immunology. 21:92-97
Functional and biochemical assays indicate a substantial contribution of intracellularly derived peptides to the MHC class II 'ligandome'. Macroautophagy, a process traditionally known for its role in cellular housekeeping and adaptation to nutrient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::359bf90eb1acc5cf8de53b3271176ddd
https://doi.org/10.1016/j.coi.2009.01.013
https://doi.org/10.1016/j.coi.2009.01.013
Publikováno v:
Cell Cycle. 7:3625-3628
During intrathymic generation of the T cell repertoire, a series of selection processes ensures that only self-MHC (Major Histocompatibility Complex) restricted and self-tolerant T cells are allowed to survive. Interactions with MHC ligands on the su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0e5f8a50c4e81192f28a2a43eaa463
https://doi.org/10.4161/cc.7.23.7121
https://doi.org/10.4161/cc.7.23.7121
Autor:
Elisabeth Paietta, Sandrine Poglio, Vanina Gabriela Da Ros, Jay P. Patel, Jeremy B. Samon, Thomas Trimarchi, Jasmin M. Siegle, Maria Dominguez, Kim De Keersmaecker, Jacob M. Rowe, Tien Huynh, Ross L. Levine, Patrik Asp, Zuojian Tang, Dolors Ferres-Marco, Michael Hadler, Adolfo A. Ferrando, Filippo Utro, Janis Racevskis, Françoise Pflumio, Aristotelis Tsirigos, Maria Sol Flaherty, Stuart M. Brown, Iannis Aifantis, Raul Rabadan, Panagiotis Ntziachristos, Jelena Nedjic, Isaura Rigo, Pieter Van Vlierberghe
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature medicine
instname
Nature medicine
T cell acute lymphoblastic leukemia (T-ALL) is an immature hematopoietic malignancy driven mainly by oncogenic activation of NOTCH1 signaling1. In this study we report the presence of loss-of-function mutations and deletions of the EZH2 and SUZ12 gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c8784ab8a0eb31dd9c6940649a5e356
http://hdl.handle.net/10261/66875
http://hdl.handle.net/10261/66875
Publikováno v:
Autophagy. 4(8)
During T cell development in the thymus, scanning of peptide/major histocompatibility (MHC) molecule complexes on the surface of thymic epithelial cells ensures that only useful (self-MHC restricted) and harmless (self-tolerant) thymocytes survive. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450a1744c1ed2158c45948695296e8ca
https://pubmed.ncbi.nlm.nih.gov/18927488
https://pubmed.ncbi.nlm.nih.gov/18927488
Publikováno v:
Nature. 455(7211)
Macro-autophagy in thymic epithelial cells is shown to contribute to endogenous antigen processing and selection of major histocompatibility complex class II (MHC II)-restricted CD4 T cells. This suggests that autophagy focuses the MHC class II/pepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af5913835a8fc69f3e503d1e60154581
https://pubmed.ncbi.nlm.nih.gov/18701890
https://pubmed.ncbi.nlm.nih.gov/18701890
Publikováno v:
Autophagy. 9:931-932
During development in the thymus, each T lymphocyte is equipped with one, essentially unique, T cell receptor (TCR)-specificity. Due to its random nature, this process inevitably also leads to the emergence of potentially dangerous T lymphocytes that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39dd8bf7678a45e7688c1256a7953844
https://doi.org/10.4161/auto.24374
https://doi.org/10.4161/auto.24374