Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jekaterina Nebogatova"'
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 617 (2024)
The potential for native proteins to serve as a platform for biocompatible, targeted, and personalized therapeutics in the context of genetic and metabolic disorders is vast. Nevertheless, their clinical application encounters challenges, particularl
Externí odkaz:
https://doaj.org/article/84950de87c0946c8ae279e2ba9c6bcbe
Autor:
Jekaterina Nebogatova, Heleri Heike Härk, Anett Puskar, Ly Porosk, Paolo Guazzi, Moataz Dowaidar, Ülo Langel, Kaido Kurrikoff
Publikováno v:
Biomolecules, Vol 13, Iss 12, p 1751 (2023)
The low bioavailability and high toxicity of plasmid DNA (pDNA)-based therapeutics pose challenges for their in vivo application. Extracellular vesicles (EVs) have great potential to overcome these limitations, as they are biocompatible native cargo
Externí odkaz:
https://doaj.org/article/47f4e8ca2d934d4f8af3f6f2f2b9d69c
Autor:
Ly Porosk, Jekaterina Nebogatova, Heleri Heike Härk, Birgit Vunk, Piret Arukuusk, Urve Toots, Mart Ustav, Ülo Langel, Kaido Kurrikoff
Publikováno v:
Pharmaceutics, Vol 14, Iss 9, p 1949 (2022)
Therapeutic proteins are currently at the apex of innovation in pharmaceutical medicine. However, their industrial production is technically challenging and improved methods for transient transfection of mammalian cell cultures are necessary. We aime
Externí odkaz:
https://doaj.org/article/c4dfbd138aa549bfabe4815d0ae62279
Autor:
Ly Porosk, Jekaterina Nebogatova, Heleri Heike Härk, Birgit Vunk, Piret Arukuusk, Urve Toots, Mart Ustav, Ülo Langel, Kaido Kurrikoff
Therapeutic proteins are currently at the hotspot of innovation in the pharmaceutical medicine. However, their industrial production is technically challenging and improved methods for transcriptional manipulation of mammalian industrial cell culture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb592c22e65ab976d7032727be8f711b
https://doi.org/10.1101/2022.03.15.484372
https://doi.org/10.1101/2022.03.15.484372
Autor:
Ly Porosk, Heleri Heike Härk, Renata Naporano Bicev, Ilja Gaidutšik, Jekaterina Nebogatova, Eger-Jasper Armolik, Piret Arukuusk, Emerson Rodrigo da Silva, Ülo Langel
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 5
Pages: 4277
Volume 24
Issue 5
Pages: 4277
Alzheimer’s disease (AD) is the most common neurodegenerative disease (ND) and the leading cause of dementia. It is characterized by non-linear, genetic-driven pathophysiological dynamics with high heterogeneity in the biological alterations and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d851cea67170fc01dc184212709aa9
https://doi.org/10.3390/ijms24054277
https://doi.org/10.3390/ijms24054277
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2383
The efficacy of transfection reagents and nanoparticles is often assessed by measuring levels of expressed reporter protein. Fluorescence and luminescence based assays provide sensitive, quantifiable and repeatable approaches. The genes expressing re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8d289d6a5abdd9c8d47465553af2b271
https://pubmed.ncbi.nlm.nih.gov/34766311
https://pubmed.ncbi.nlm.nih.gov/34766311
Publikováno v:
Methods in Molecular Biology ISBN: 9781071617519
The efficacy of transfection reagents and nanoparticles is often assessed by measuring levels of expressed reporter protein. Fluorescence and luminescence based assays provide sensitive, quantifiable and repeatable approaches. The genes expressing re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85b53ff41f31125e6b470d11376bdb60
https://doi.org/10.1007/978-1-0716-1752-6_33
https://doi.org/10.1007/978-1-0716-1752-6_33