Derivatives of 4-methyl-1,2,3-benzoxathiazine 2,2-dioxide as selective inhibitors of human carbonic anhydrases IX and XII over the cytosolic isoforms I and II

Autor: Jekaterīna Ivanova, Morteza Abdoli, Alessio Nocentini, Raivis Žalubovskis, Claudiu T. Supuran

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)

A series of 4-methyl-1,2,3-benzoxathiazine-2,2-dioxides with various substituents in 5, 6 or 7 positions was obtained from corresponding 2’-hydroxyacetophenones in their reaction with sulphamoyl chloride. 6- and 7-aryl substituted 4-methyl-1,2,3-be

Externí odkaz: https://doaj.org/article/8c6ab762574840a493a4d802c308b153

1,2,3-Benzoxathiazine-2,2-dioxides – effective inhibitors of human carbonic anhydrases

Autor: Jekaterina Ivanova, Morteza Abdoli, Alessio Nocentini, Raivis Žalubovskis, Claudiu T. Supuran

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1, Pp 225-238 (2023)

A series of 1,2,3-benzoxathiazine-2,2-dioxides possessing various substituents in the 5, 7, or 8 position was obtained from corresponding 2-hydroxybenzaldehydes in their reaction with sulfamoyl chloride. 5-, 7-, and 8-aryl substituted 1,2,3-benzoxath

Externí odkaz: https://doaj.org/article/33ffeb43bc8347a7a75b6913fe2231aa

Reactivity of Aziridine-2-Carboxamide (Leakadine) with Nucleophiles in Aqueous Solutions*

Autor: Ivars Kalvinsh, Edvards Liepinsh, Jekaterīna Ivanova, Raivis Žalubovskis, Rihards Aleksis, Kristaps Jaudzems

Publikováno v: Chemistry of Heterocyclic Compounds. 49:1589-1598

We describe studies of aziridine-2-carboxamide (Leakadine) reactivity with N-, O-, and S-nucleophiles in aqueous solutions using NMR spectroscopy and chemical synthesis. The results show that nucleophilic ring opening reactions of Leakadine with N- a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c468e505f6ceec5c10c178243b783b42
https://doi.org/10.1007/s10593-014-1410-x

European General Practice Research Network (EGPRN): Abstracts from the EGPRN conference in Riga, Latvia, 11–14 May 2017. Theme: ‘Reducing the risk of chronic diseases in general practice/family medicine’

Autor: Ruth Kalda, Vija Silina, Sabine Bayen-Krohn, Nathalie Deruytter, Sven Streit, Marjolein Verschoor, Nicolas Rodondi Bonfim Daiana, Robert A. Burman, Tuz Canan, Claire Collins, Kitanovska Gerasimovska Biljana, Sandra Gintere, Raquel Bravo Gómez, Kath Hoffmann, Tugrul Biyiklioglu, Pavlo Kolesnyk, Enkeleint-Aggelos Mechili, Michael Harris, Yochai Schonmann, O. Bleich, Andre Matalon, Hanny Yeshua, Shlomo Vinker, Judit Prus, Doron S. Comaneshter, Arnon D. Cohen, Amnon Lahad, Ludmila Terjajeva, Iveta Skurule, Jean Yves Le Reste, Ronan Le Mer, Jeremy Derriennic, Michele odorico, Delphine le Goff, Sophie Lalande, Patrice Nabbe, Bernard Le Floch, Alice Billot Grasset, Jean Baptiste Nousbaum, Marie O’Shea, Margo Wrigley, Jim Ryan, Brian Osborne, Jogin Thakore, Donal O. Hanlon, Pearse Finegan, Elina Skuja, Elin Kristina Zackrisson, Ilze Skuja, Stefan Bösner, Jamal Abushi, Norbert Donner-Banzhoff, Erik Stolper, Paul Van Royen, Margje van de Wiel, Loes van Bokhoven, Geert Jan Dinant, Katharina Schmalstieg, Wolfgang Himmel, Eva Hummers, Maxime Pautrat, Catherine Laporte, Jean Pierre Lebeau, Jekaterina Ivanova, Miguel-Angel Muñoz, Helene Vaillant-Roussel, Heidrun Lingner, Jacopo Demurtas, Ana-Luisa Neves, Peter Torsza, Radost Asenova, Zalika Klemenc-Ketis, Liam Glynn, Hayriye Kulbay, José-Maria Verdú, Hava Tabenkin, Melissa Nothnagle, Jeffrey Borkan, Kathrin Schlöszler, Robert Splittgerber, Anne Kühlwind, Ausra Saxvik, Anna Franz, Inger Hagqvist, Stig Rödjer, Göran Bondjers, Marija Petek Šter, Polona Selič, Johannes Hauswaldt, Stephanie Heinemann, Ann Verhoeven, Elke Leuridan, Lieve Peremans, Roy Remmen, Leonard Mada, Roxana Tilea

Publikováno v: European Journal of General Practice, Vol 23, Iss 1, Pp 227-240 (2017)

Externí odkaz: https://doaj.org/article/08b5c334fd97436a8c8ef04a4bdd2b96