Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Jejoong Yoo"'
Autor:
Ki-Baek Jeong, Minju Ryu, Jin-Sik Kim, Minsoo Kim, Jejoong Yoo, Minji Chung, Sohee Oh, Gyunghee Jo, Seong-Gyu Lee, Ho Min Kim, Mi-Kyung Lee, Seung-Wook Chi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Efficient screening of protein-drug interactions (PDIs) has been impeded by the limitations of current biophysical approaches. Here, the authors present a funneled YaxAB nanopore sensor which allows label-free, single-molecule detection of proteins a
Externí odkaz:
https://doaj.org/article/54c373ddae0b4cd79378d22673a63deb
Autor:
Seu-Na Lee, Hwa-Jin Cho, Hyeongseop Jeong, Bumhan Ryu, Hyuk-Joon Lee, Minsoo Kim, Jejoong Yoo, Jae-Sung Woo, Hyung Ho Lee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Connexin 36 (Cx36) gap junction channel is responsible for signal transmission in electrical synapses. Here, the authors determine cryo-EM structures of Cx36, providing insights into a potential role of lipids in the channel gating.
Externí odkaz:
https://doaj.org/article/be34f9ad35c84967aec756611a123668
Autor:
Hyuk-Joon Lee, Hyung Jin Cha, Hyeongseop Jeong, Seu-Na Lee, Chang-Won Lee, Minsoo Kim, Jejoong Yoo, Jae-Sung Woo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Gap junction intercellular channels (GJIChs) facilitate direct communication between adjacent cells. Here, authors provide high-resolution information on dynamic structural changes in Cx43 GJICh that are necessary to understand the gating mechanism.
Externí odkaz:
https://doaj.org/article/3ade39c189824e13bf2b039251b987e1
Publikováno v:
ACS Omega, Vol 6, Iss 29, Pp 18728-18736 (2021)
Externí odkaz:
https://doaj.org/article/d0cab0751d6b43d6a61b0a3a169ea5fe
Autor:
Alexander Ohmann, Chen-Yu Li, Christopher Maffeo, Kareem Al Nahas, Kevin N. Baumann, Kerstin Göpfrich, Jejoong Yoo, Ulrich F. Keyser, Aleksei Aksimentiev
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Mimicking enzyme function and improving upon it is a challenge facing nanotechnology. Here the authors design a DNA nanostructure that catalyzes the transport of lipids between bilayers at a rate three orders of magnitude higher than biological enzym
Externí odkaz:
https://doaj.org/article/2f5231c7aff4488f9f6fa528592e67b0
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
Theoretical studies suggest that homologous DNA duplexes can preferentially associate with one another in the absence of proteins. Here, the authors show that GC-rich DNA with methylated cytosine and AT-rich DNA duplexes associate more strongly than
Externí odkaz:
https://doaj.org/article/c40d2f4f315e48da9b0b3d60a2ebb5fa
Autor:
Thuy T. M. Ngo, Jejoong Yoo, Qing Dai, Qiucen Zhang, Chuan He, Aleksei Aksimentiev, Taekjip Ha
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Cytosine modifications are important epigenetic markers yet their physical influence on DNA is not well understood. Here, Ngo et al. show that different alterations affect DNA flexibility, suggesting a mechanism where modifications change accessibili
Externí odkaz:
https://doaj.org/article/0efdd629e1b94ac2be9c3b50a9bcee44
Publikováno v:
Soft Matter. 18:3313-3317
Protein phase separation in biological systems has captured the attention of scientists in the last decade; however, the main mechanism underlying protein phase separation in cells remains unclear. Biologists, physicists, and chemists have all tried
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b9285bad6308567d1224628c686291
https://doi.org/10.1039/d2sm00384h
https://doi.org/10.1039/d2sm00384h
Publikováno v:
Nucleic Acids Research
Eukaryotic genome and methylome encode DNA fragments’ propensity to form nucleosome particles. Although the mechanical properties of DNA possibly orchestrate such encoding, the definite link between ‘omics’ and DNA energetics has remained elusi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f1d3037792f00462febe2ac44987378
https://doi.org/10.1093/nar/gkab967
https://doi.org/10.1093/nar/gkab967
Autor:
Jejoong Yoo
Publikováno v:
Journal of the Korean Physical Society. 78:461-466
The molecular dynamics simulation using the so-called force field is a computational method to investigate the conformational stability and dynamics of various biomolecules, including proteins and nucleic acids. While a force-balanced force field is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::756cc94addb4c35a46b0fbe29462e2eb
https://doi.org/10.1007/s40042-021-00063-9
https://doi.org/10.1007/s40042-021-00063-9