Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jehanne Hassan"'
Autor:
Victoria Jennings, Kevin Harrington, Hardev Pandha, Alan Melcher, Adel Samson, Fiona Errington-Mais, Victoria Roulstone, Eva Crespo-Rodriguez, Galabina Bozhanova, Shane Foo, Emmanuel C Patin, Martin McLaughlin, Malin Pedersen, Richard Vile, Joan Kyula, Jehanne Hassan, Lizzie Appleton, Charleen ML Chan Wah Hak, Gabby Baker, Edward Armstrong, Matthew Chiu, Masahiro Ono
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 3 (2022)
Background Combination herpes simplex virus (HSV) oncolytic virotherapy and BRAF inhibitors (BRAFi) represent promising immunogenic treatments for BRAF mutant melanoma, but an improved understanding of the immunobiology of combinations is needed to i
Externí odkaz:
https://doaj.org/article/316204113b0e4019ac28423a26ae7cf2
Autor:
Elizabeth Appleton, Jehanne Hassan, Charleen Chan Wah Hak, Nanna Sivamanoharan, Anna Wilkins, Adel Samson, Masahiro Ono, Kevin J. Harrington, Alan Melcher, Erik Wennerberg
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Cancer patients with low or absent pre-existing anti-tumour immunity (“cold” tumours) respond poorly to treatment with immune checkpoint inhibitors (ICPI). In order to render these patients susceptible to ICPI, initiation of de novo tumour-target
Externí odkaz:
https://doaj.org/article/e7dcf450480948f789c0097fc31a8b73
Autor:
José Almeida-Santos, Rita Berkachy, Chanidapa Adele Tye, Jehanne Hassan, Bahire Kalfaoglu, Murray E. Selkirk, Masahiro Ono
CD4 T-cells require T-cell receptor (TCR) signalling for their activation and differentiation. Foxp3+ regulatory T-cells (Treg) are dependent on TCR signals for their differentiation and suppressive function. However, it is not fully known how TCR si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e646650249f636ca2821596d81a72980
https://doi.org/10.1101/2022.07.21.500987
https://doi.org/10.1101/2022.07.21.500987
Autor:
Jehanne Hassan, Elizabeth Appleton, Bahire Kalfaoglu, Malin Pedersen, José Almeida-Santos, Hisashi Kanemaru, Nobuko Irie, Shane Foo, Omnia Reda, Benjy J.Y. Tan, Il-mi Okazaki, Taku Okazaki, Yorifumi Satou, Kevin Harrington, Alan Melcher, Masahiro Ono
The blockade of the immune checkpoints PD-1 and CTLA-4 enhances T cell response. However, it is largely unknown how antigen-reactive T cells regulate their checkpoint expression in vivo and whether and how the checkpoint blockade can change activatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db8cb1d9af3e601a3c1d0591c82c161e
https://doi.org/10.1101/2022.07.19.500582
https://doi.org/10.1101/2022.07.19.500582
Autor:
Galabina Bozhanova, Jehanne Hassan, Lizzie Appleton, Victoria Jennings, Shane Foo, Martin McLaughlin, Charleen ML Chan Wah Hak, Emmanuel C Patin, Eva Crespo-Rodriguez, Gabby Baker, Edward Armstrong, Matthew Chiu, Hardev Pandha, Adel Samson, Victoria Roulstone, Joan Kyula, Richard Vile, Fiona Errington-Mais, Malin Pedersen, Kevin Harrington, Masahiro Ono, Alan Melcher
Publikováno v:
Journal for ImmunoTherapy of Cancer. 10:e004410
BackgroundCombination herpes simplex virus (HSV) oncolytic virotherapy and BRAF inhibitors (BRAFi) represent promising immunogenic treatments for BRAF mutant melanoma, but an improved understanding of the immunobiology of combinations is needed to im