Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jehangir Cama"'
Autor:
Jehangir Cama, Kareem Al Nahas, Marcus Fletcher, Katharine Hammond, Maxim G. Ryadnov, Ulrich F. Keyser, Stefano Pagliara
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Antimicrobial resistance challenges the ability of modern medicine to contain infections. Given the dire need for new antimicrobials, polypeptide antibiotics hold particular promise. These agents hit multiple targets in bacteria starting wit
Externí odkaz:
https://doaj.org/article/7d4c17a3d49a4890b5caf90ea541e8d6
Autor:
Liam Ives, Alizée Pace, Fabian Bor, Qingshen Jing, Tom Wade, Jehangir Cama, Vikas Khanduja, Sohini Kar-Narayan
Publikováno v:
Materials & Design, Vol 219, Iss , Pp 110747- (2022)
Balancing forces within weight-bearing joints such as the hip during joint replacement is essential for implant longevity. Minimising implant failure and the corresponding need for expensive and difficult revision surgery is vital to both improve the
Externí odkaz:
https://doaj.org/article/c34f23d9b3854952b3f45f48f748d276
Autor:
Olivia Goode, Ashley Smith, Ashraf Zarkan, Jehangir Cama, Brandon M. Invergo, Daaniyah Belgami, Santiago Caño-Muñiz, Jeremy Metz, Paul O’Neill, Aaron Jeffries, Isobel H. Norville, Jonathan David, David Summers, Stefano Pagliara
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Persister and viable but non-culturable (VBNC) cells are two clonal subpopulations that can survive multidrug exposure via a plethora of putative molecular mechanisms. Here, we combine microfluidics, time-lapse microscopy, and a plasmid-enco
Externí odkaz:
https://doaj.org/article/6d1f31061d5a4954937de418453ed324
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93168 (2014)
Indole has diverse signalling roles, including modulation of biofilm formation, virulence and stress responses. Changes are induced by indole concentrations of 0.5-1.0 mM, similar to those found in the supernatant of Escherichia coli stationary phase
Externí odkaz:
https://doaj.org/article/9d4b676f1bc746a29f321d8804f623e8
Autor:
Kareem Al Nahas, Marcus Fletcher, Katharine Hammond, Christian Nehls, Jehangir Cama, Maxim G. Ryadnov, Ulrich F. Keyser
Funder: Phospholipid Research Center
Funder: Engineering and Physical Sciences Research Council
Funder: Trinity College, University of Cambridge
Funder: Department for Business, Energy and Industrial Strategy, UK Government
Host d
Funder: Engineering and Physical Sciences Research Council
Funder: Trinity College, University of Cambridge
Funder: Department for Business, Energy and Industrial Strategy, UK Government
Host d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb462d5b870e7e56fdecdc620d209ae
Autor:
Katharine Hammond, K. Al Nahas, Marcus Fletcher, Stefano Pagliara, Jehangir Cama, Maxim G. Ryadnov, Ulrich F. Keyser
Antimicrobial resistance challenges the ability of modern medicine to contain infections. Given the dire need for new antimicrobials, peptide antibiotics hold particular promise. These agents hit multiple targets in bacteria starting with their most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9aa9b70a7db0e1d63d7e09c1124a94e2
https://doi.org/10.1101/2021.09.08.459503
https://doi.org/10.1101/2021.09.08.459503
Autor:
Alizée Pace, Tom Wade, Vikas Khanduja, Qingshen Jing, Jehangir Cama, Liam Ives, Fabian Bor, Sohini Kar-Narayan
Balancing forces within weight-bearing joints such as the hip during joint replacement surgeries is essential for implant longevity. Minimising implant failure is vital to improve patient wellbeing and alleviate pressure on healthcare systems. With i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dab95dabe96a5f707508d38cc3d9e42
https://doi.org/10.1101/2021.08.19.456934
https://doi.org/10.1101/2021.08.19.456934
Autor:
Jehangir Cama, Marcus Fletcher, Kareem Al Nahas, Christian Nehls, Maxim G. Ryadnov, Katharine Hammond, Ulrich F. Keyser
Host defense or antimicrobial peptides hold promise for providing new pipelines of effective antimicrobial agents. Their activity quantified against model phospholipid membranes is fundamental to a detailed understanding of their structure-activity r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::224d95b20ee42f0aa29cfe01f128d713
https://doi.org/10.1101/2021.08.13.455434
https://doi.org/10.1101/2021.08.13.455434
Autor:
Jeremy Metz, Stefano Pagliara, Isobel H. Norville, Ashraf Zarkan, Aaron R. Jeffries, Jehangir Cama, David K. Summers, Santiago Caño-Muñiz, Olivia Goode, Paul O'Neill, Jonathan David, Brandon M. Invergo, Daaniyah Belgami, Ashley Smith
Publikováno v:
mBio
mBio, Vol 12, Iss 4 (2021)
mBio, Vol 12, Iss 4 (2021)
Persister and viable but non-culturable (VBNC) cells are two clonal subpopulations that can survive multidrug exposure via a plethora of putative molecular mechanisms. Here, we combine microfluidics, time-lapse microscopy, and a plasmid-encoded fluor
Autor:
Katharine Hammond, Flaviu Cipcigan, Bart W. Hoogenboom, Marcus Fletcher, Helen Lewis, Phillip J. Stansfeld, Patrick W. Simcock, Jason Crain, Ulrich F. Keyser, Fausto Martelli, Mark S.P. Sansom, Jehangir Cama, Kareem Al Nahas, Jascindra Ravi, Valeria Losasso, Stefano Pagliara, Maxim G. Ryadnov
Publikováno v:
ACS Nano
ACS nano
ACS nano
Disruption of cell membranes is a fundamental host defense response found in virtually all forms of life. The molecular mechanisms vary but generally lead to energetically favored circular nanopores. Here, we report an elaborate fractal rupture patte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a5bebdd5de53e144ca8a16971aa6a0
http://wrap.warwick.ac.uk/154253/1/WRAP-Switching-cytolytic-nanopores-antimicrobial-fractal-ruptures-single-side-chain-mutation-2021.pdf
http://wrap.warwick.ac.uk/154253/1/WRAP-Switching-cytolytic-nanopores-antimicrobial-fractal-ruptures-single-side-chain-mutation-2021.pdf