Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Jehan Mardan"'
Autor:
Charlotte M. Niemeyer, Perihan Mir, Azadeh Zahabi, Cornelia Zeidler, Malte U Ritter, Tim Ripperger, Masoud Nasri, Siarhei Kandabarau, Anna Solovyeva, Benjamin Dannenmann, Benedikt Oswald, Maksim Klimiankou, Doris Steinemann, Patricia Arreba-Tutusaus, Jehan Mardan, Nico Lachmann, Julia Skokowa, Miriam Erlacher, Karl Welte, Thomas Moritz, Martina Konantz, Frederic Stein, Tatsuya Morishima, Claudia Lengerke
Publikováno v:
Cell Stem Cell. 28:906-922.e6
Severe congenital neutropenia (CN) is a pre-leukemic bone marrow failure syndrome that can evolve to acute myeloid leukemia (AML). Mutations in CSF3R and RUNX1 are frequently observed in CN patients, although how they drive the transition from CN to