Výsledky vyhledávání - "Jegot, Gwenhael"

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Profiling of FSHR Negative Allosteric Modulators on LH/CGR Reveals Biased Antagonism with Implications in Steroidogenesis

Autor: Ayoub, Mohammed Akli, Yvinec, Romain, Jégot, Gwenhaël, Dias, James A., Poli, Sonia-Maria, Poupon, Anne, Crépieux, Pascale, Reiter, Eric

Publikováno v: Molecular and Cellular Endocrinology, 436:10--22 (2016)

Biased signaling has recently emerged as an interesting mean to modulate the function of many G protein-coupled receptors (GPCRs). Previous studies reported two negative allosteric modulators (NAMs) of follicle-stimulating hormone receptor (FSHR), AD

Externí odkaz: http://arxiv.org/abs/1808.00310

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Akademický článek

Biased signalling in follicle stimulating hormone action

Autor: Landomiel, Flavie, Gallay, Nathalie, Jégot, Gwenhael, Tranchant, Thibaud, Durand, Guillaume, Bourquard, Thomas, Crépieux, Pascale, Poupon, Anne, Reiter, Eric

Publikováno v: In Molecular and Cellular Endocrinology 25 January 2014 382(1):452-459

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Two Negative Allosteric Modulators (NAMS) display biased activities on FSH-induced β-arrestin recruitment at the FSH-R

Autor: Jegot, Gwenhael, Poupon, Anne, Crepieux, Pascale, Langonné Gallay, Nathalie, Poli, Sonia-Maria, Dias, James A., Reiter, Eric

National audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::eabf6e9aa88ddfbe53db948893f81802
https://hal.inrae.fr/hal-02740119

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Predicting the 3D structure of macromolecular assemblies using PRIOR

Autor: Bourquard, Thomas, Landomiel, Flavie, Jegot, Gwenhael, Decourtye, Jérémy, Maurel, Marie-Christine, Reiter, Eric, Crépieux, Pascale, Ritchie, David, Azé, Jérôme, Poupon, Anne

Publikováno v: International Conference on Gonadotropins & Receptors
International Conference on Gonadotropins & Receptors, Sep 2014, Tours, France. 2014, ICGRIII International Conference on Gonadotropins & Receptors
International Conference on Gonadotropins & Receptors, Sep 2014, Tours, France., 2014, ICGRIII International Conference on Gonadotropins & Receptors

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::bd62b11c8d005c934d6cbc418f465fb9
https://hal.inrae.fr/hal-02743415

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Thermal stability of Single-Chain bovine FSH with hCG-CTP linker

Autor: Jouanny, Camille, Mariot, Julie, Amrane, Samir, Klett, Danièle, Cahoreau, Claire, Jegot, Gwenhael, Bourdoncle, Anne, Combarnous, Yves

National audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6f81623f3122763915d9261a21b54f6e
https://hal.inrae.fr/hal-02739065

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S680 single nucleotide polymorphism of the FSH receptor increases FSH-induced beta-arrestin recruitment while reducing beta-arrestin-dependent translocation of active PKA to the nucleus

Autor: Tranchant, Thibaud, Durand, Guillaume, Landomiel, Flavie, Jegot, Gwenhael, Gallay, Nathalie, Piketty, Vincent, Gauthier, Christophe, Ulloa-Aguirre, Alfredo, Bourquard, Thomas, Poupon, Anne, Crepieux, Pascale, Royère, Dominique, Reiter, Eric

Publikováno v: Gordon Research Conference in Molecular Pharmacology
Gordon Research Conference in Molecular Pharmacology, Apr 2013, Lucca (Barga), Italy. 2013

International audience; A polymorphism at position 680 (N→S) of the human FSH receptor (FSHR) has been associated with an increased resistance to FSH in women bearing an S/S genotype, whereas the effects of ovarian hyperstimulation syndrome (OHSS)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ca8f2744413225ce6700138460076df7
https://hal.inrae.fr/hal-02811177

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