Zobrazeno 1 - 10
of 526
pro vyhledávání: '"Jeggo, P. A."'
Autor:
Martin D. Burkhalter, Tom Stiff, Lars D. Maerz, Teresa Casar Tena, Heike Wiese, Julian Gerhards, Steffen A. Sailer, Linh Anna Trúc Vu, Max Duong Phu, Cornelia Donow, Marius Alupei, Sebastian Iben, Marco Groth, Sebastian Wiese, Joseph A. Church, Penelope A. Jeggo, Melanie Philipp
Publikováno v:
Cell Death and Disease, Vol 15, Iss 9, Pp 1-14 (2024)
Abstract The WD repeat-containing protein 4 (WDR4) has repeatedly been associated with primary microcephaly, a condition of impaired brain and skull growth. Often, faulty centrosomes cause microcephaly, yet aberrant cilia may also be involved. Here,
Externí odkaz:
https://doaj.org/article/c7c8e616bb0a44d686f248d5e16d846c
Akademický článek
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Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Ines S Amorim, Sylvie Challal, Laetitia Cistarelli, Thierry Dorval, Laurene Abjean, Manuelle Touzard, Nicolas Arbez, Arnaud François, Fany Panayi, Ross Jeggo, Erika Cecon, Atsuro Oishi, Julie Dam, Ralf Jockers, Patricia Machado
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0283941 (2023)
Intracellular accumulation of tau protein is a hallmark of Alzheimer's Disease and Progressive Supranuclear Palsy, as well as other neurodegenerative disorders collectively known as tauopathies. Despite our increasing understanding of the mechanisms
Externí odkaz:
https://doaj.org/article/8015c54627e64350a7b3b92db676e019
Autor:
François-Xavier Blaudin de Thé, Benjamin Lassus, Ari W. Schaler, Stephanie L. Fowler, Chris N. Goulbourne, Ross Jeggo, Clotilde Mannoury la Cour, Mark J. Millan, Karen E. Duff
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-19 (2021)
Abstract In Alzheimer’s disease and related tauopathies, trans-synaptic transfer and accumulation of pathological tau from donor to recipient neurons is thought to contribute to disease progression, but the underlying mechanisms are poorly understo
Externí odkaz:
https://doaj.org/article/6ec10d2a588a40fb82206e796520623e
Autor:
Selvakumar Anbalagan, Cecilia Ström, Jessica A. Downs, Penny A. Jeggo, David McBay, Anna Wilkins, Kai Rothkamm, Kevin J. Harrington, John R. Yarnold, Navita Somaiah
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Recent clinical trials in breast and prostate cancer have established that fewer, larger daily doses (fractions) of radiotherapy are safe and effective, but these do not represent personalised dosing on a patient-by-patient basis. Understand
Externí odkaz:
https://doaj.org/article/c9e7edacfb97484e949e3d81da55de3a
Autor:
Bharath Sampadi, Sylvia Vermeulen, Branislav Mišovic, Jan J. Boei, Tanveer S. Batth, Jer-Gung Chang, Michelle T. Paulsen, Brian Magnuson, Joost Schimmel, Hanneke Kool, Cyriel S. Olie, Bart Everts, Alfred C. O. Vertegaal, Jesper V. Olsen, Mats Ljungman, Penny A. Jeggo, Leon H. F. Mullenders, Harry Vrieling
Publikováno v:
Cells, Vol 11, Iss 23, p 3794 (2022)
Cancer risk after ionizing radiation (IR) is assumed to be linear with the dose; however, for low doses, definite evidence is lacking. Here, using temporal multi-omic systems analyses after a low (LD; 0.1 Gy) or a high (HD; 1 Gy) dose of X-rays, we s
Externí odkaz:
https://doaj.org/article/c1d30103c56243f683bc88e1eec647e6
Publikováno v:
BMJ Open Quality, Vol 9, Iss 4 (2020)
Smoking tobacco is a major public health issue and a significant cause of increased mortality. People with a first episode of psychosis are more likely to smoke and the subgroup that goes on to have schizophrenia will have a significantly reduced lif
Externí odkaz:
https://doaj.org/article/0ab8e565cad0481aad88d0a109e29548
Publikováno v:
Radiation Research, 2005 Jul 01. 164(1), 53-62.
Externí odkaz:
https://www.jstor.org/stable/3581513