Výsledky vyhledávání - "Jeffry S. Mann"

Comparison of MR Contrast–enhancing Properties of Albumin-(biotin)10-(gadopentetate)25, a Macromolecular MR Blood Pool Contrast Agent, and Its Microscopic Distribution

Autor: Robert C. Brasch, Jeffry S. Mann, Heidi C. Roberts, Franci Demsar, Timothy P.L. Roberts, Werner Rosenau, Cornelis F. van Dijke, Michael F. Wendland

Publikováno v: Academic Radiology. 9:S257-S260

Macromolecular contrast media (MMCM) specifically designed to enhance the blood pool do not substantially penetrate the endothelial barrier of most normal tissues but will penetrate tumor microvascular endothelium readily. Consequently, steady increa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a65be9ca289931b85c29c762a232b507
https://doi.org/10.1016/s1076-6332(03)80451-8

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Quantification of liver blood volume: comparison of ultra short ti inversion recovery echo planar imaging (ulstir-epi), with dynamic 3d-gradient recalled echo imaging

Autor: Cornelis F. van Dijke, Timothy P.L. Roberts, Robert C. Brasch, David M. Shames, Heidi C. Schwickert, Alexander R. Disston, Jeffry S. Mann, Andreas Mühler

Publikováno v: Magnetic Resonance in Medicine. 34:845-852

An ultra-short TI inversion recovery echo-planar imaging (ULSTIR-EPI) sequence was designed to reduce the influence of water exchange on fractional tissue blood volume (BV) estimation by measurement of T1-changes induced by a gadolinium-based macromo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc9f10f6e07c2565769f5b8f49cbf70
https://doi.org/10.1002/mrm.1910340609

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Molecular amplifiers: synthesis and functionalization of a poly(aminopropyl)dextran bearing a uniquely reactive terminus for univalent attachment to biomolecules

Autor: Jeffry S. Mann, Jin Cheng Huang, John F. W. Keana

Publikováno v: Bioconjugate Chemistry. 3:154-159

The synthesis and characterization of the versatile dextran-based molecular amplifier 6 is described. Dextran (Mr = 40,200) was selectively monofunctionalized in high yield at its reducing terminus via reductive amination with 2-(4-nitrophenyl)ethyla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88161ffbc5a1b7a34533db1aad2fd412
https://doi.org/10.1021/bc00014a010

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Novel nitroxides for spin-labelling, -trapping, and magnetic resonance imaging applications

Autor: Jeffry S. Mann, Jane H. Park, James M. May, Brian J. Sweetman, V. S. Prabhu, Gerald M. Rosen, Laszlo Lex, Yexin Wu, John F. W. Keana, Sovitj Pou

Publikováno v: Pure and Applied Chemistry. 62:201-205

We describe the synthesis of the isotopically labelled nitrone spin traps 7,9, and 10, and spin labelled cytochalasin B derivatives 15 23. We describe a new general route to proxy1 nitroxide spin labelled fatty acids, for example, 28 and 29, and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd8918bb3d727c2cbb88a1e2aaff6b84
https://doi.org/10.1351/pac199062020201

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Comparison of gadopentetate dimeglumine and albumin-(Gd-DTPA)30 for microvessel characterization in an intracranial glioma model

Autor: Jeffry S. Mann, James Fick, Kenneth Aldape, Timothy P.L. Roberts, Robert C. Brasch, Susanne Ostrowitzki, Mark A. Israel, Michael F. Wendland

Publikováno v: Journal of magnetic resonance imaging : JMRI. 8(4)

To compare the performance of macromolecular albumin gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA)30 and low molecular weight gadopentetate dimeglumine for microvessel characterization, we examined an intracranial 9L glioma model in which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48247b598181dee990a759d3f649cab3
https://pubmed.ncbi.nlm.nih.gov/9702880

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Magnetic resonance imaging detects suppression of tumor vascular permeability after administration of antibody to vascular endothelial growth factor

Autor: Melnyk O, Jeffry S. Mann, Timothy P.L. Roberts, Napoleone Ferrara, van Bruggen N, Robert C. Brasch, Christine D. Pham, Robert L. Cohen

Publikováno v: Cancer investigation. 16(4)

Macromolecular contrast medium-enhanced magnetic resonance imaging (MR/) and tumor-volume measurements were applied to monitor the effects of anti-vascular endothelial growth factor (anti-VEGF) antibody on microvascular characteristics and tumor grow

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b4e57979fab9f11a1061f7b92f6b133
https://pubmed.ncbi.nlm.nih.gov/9589031

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A MRI spatial mapping technique for microvascular permeability and tissue blood volume based on macromolecular contrast agent distribution

Autor: Franci Demsar, Jeffry S. Mann, Robert C. Brasch, David M. Shames, Maythem Saeed, Heidi C. Schwickert, Cornelis F. van Dijke, Timothy P.L. Roberts

Publikováno v: Magnetic resonance in medicine. 37(2)

A rapid and automated method for two-dimensional spatial depiction (mapping) of quantitative physiological tissue characteristics derived from contrast enhanced MR imaging was developed and tested in disease models of cancer, inflammation, and myocar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eabf55828c4b13e5fc6752468e398a5
https://pubmed.ncbi.nlm.nih.gov/9001148

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Assessing tumor angiogenesis using macromolecular MR imaging contrast media

Autor: Ostap Melnyk, Timothy P.L. Roberts, Christine D. Pham, Robert C. Brasch, Nick Van Bruggen, Kees Van Dijke, David M. Shames, Susanne Ostrowitzki, Jeffry S. Mann

Publikováno v: Journal of magnetic resonance imaging : JMRI. 7(1)

MRI enhanced with a macromolecular contrast medium (MMCM) has previously been shown to estimate tumor microvascular characteristics that correlate closely with histologic microvascular density, an established surrogate of tumor angiogenesis. A simila

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2ac68b6c8c2061bb2a037d1ef9d19f3
https://pubmed.ncbi.nlm.nih.gov/9039595

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Mapping abnormal synovial vascular permeability in temporomandibular joint arthritis in the rabbit using MRI

Autor: David M. Shames, Charles Peterfy, Timothy P.L. Roberts, S. Tomazic, Franci Demsar, B. A. Kirk, Sunil Kapila, Jeffry S. Mann, R C Brasch, C. F. Van Dijke

Publikováno v: Scopus-Elsevier

An automated method for two-dimensional spatial depiction (mapping) of quantitative physiological tissue characteristics derived from contrast-enhanced MRI was applied to a model of inflammatory disease represented by antigen-induced arthritis of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7956ff870688ace52698737434addec
https://pubmed.ncbi.nlm.nih.gov/9010085

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