Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jeffry S Kelley"'
Autor:
Darin J Falk, Meghan S Soustek, Adrian Gary Todd, Cathryn S Mah, Denise A Cloutier, Jeffry S Kelley, Nathalie Clement, David D Fuller, Barry J Byrne
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 2, Iss , Pp - (2015)
Pompe disease is an autosomal recessive genetic disorder characterized by a deficiency of the enzyme responsible for degradation of lysosomal glycogen (acid α-glucosidase (GAA)). Cardiac dysfunction and respiratory muscle weakness are primary feat
Externí odkaz:
https://doaj.org/article/442ce2508cf241e9bda6b41c905115b6
Primers used in the study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92dcba528e172105648668608ebcaf7b
https://doi.org/10.1158/1541-7786.22527710.v1
https://doi.org/10.1158/1541-7786.22527710.v1
The overlapped DEGs in MOLM14 cells and MV4-11 cells after FLT3-ITD inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ad82949b73bb25f36ea60ed10ae2ae
https://doi.org/10.1158/1541-7786.22527707.v1
https://doi.org/10.1158/1541-7786.22527707.v1
S1. Analysis of differential gene expression in MV4-11 cells with or without FLT3 TKIs. S2.Expression of GAMT, SLC7A1 and SLC6A9 in AML cells (n=173) from TCGA LAML dataset and normal bone marrow (BM) cells (n=70) from GTEx database. S3. FLT3-ITD N51
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00cc6487f73e8d41fcacc9d72a27ec76
https://doi.org/10.1158/1541-7786.22527713
https://doi.org/10.1158/1541-7786.22527713
Publikováno v:
Molecular cancer research : MCR. 20(2)
FMS-like tyrosine kinase 3 (FLT3) is one of the most frequently mutated genes in acute myeloid leukemia (AML), with the most common mutation being internal tandem duplications (ITD). The presence of FLT3-ITD in AML carries a particularly poor prognos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed4856e94e14ac888328e82a9a46f57
https://pubmed.ncbi.nlm.nih.gov/34635505
https://pubmed.ncbi.nlm.nih.gov/34635505
Autor:
Kerry O. Cresawn, Melissa A. Lewis, Martha Campbell-Thompson, Barry J. Byrne, Jeffry S. Kelley, Sean Germain, Denise A. Cloutier, Thomas J. Conlon, Darin J. Falk, David D. Fuller, Cathryn Mah, Thomas J. Fraites, Lara R. DeRuisseau
Publikováno v:
Molecular Therapy. 18:502-510
Pompe disease is a muscular dystrophy that results in respiratory insufficiency. We characterized the outcomes of targeted delivery of recombinant adeno-associated virus serotype 1 (rAAV2/1) vector to diaphragms of Pompe mice with varying stages of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1da3eb92682c30bef5a153ecc148f70e
https://doi.org/10.1038/mt.2009.305
https://doi.org/10.1038/mt.2009.305
Autor:
Cheryl Roberts, Denise A. Cloutier, Thomas J. Conlon, Barry J. Byrne, Stacy Porvasnik, Lynn A. Combee, Kirsten E. Erger, Saleem Islam, Nathalie Clement, Travis Cossette, Corinne R. Abernathy, Jeffry S. Kelley
Publikováno v:
Human gene therapy. Clinical development. 24(3)
A biodistribution and toxicology study was performed to test the acute toxicities of intradiaphragmatic injection of a recombinant adeno-associated virus (rAAV) 2/1-human acid alpha-Glucosidase (hGAA) driven by a cytomegalovirus (CMV) promoter (rAAV1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df8b1f8276874b65eeebb51d6a4ec69b
https://pubmed.ncbi.nlm.nih.gov/24021025
https://pubmed.ncbi.nlm.nih.gov/24021025
Publikováno v:
Journal of Biological Chemistry. 268:2969-2975
Purification and sequencing of proteins from cardiac sarcoplasmic reticulum (SR) vesicles have provided a framework for the study of SR function. Included among the SR proteins so far investigated are a collection of intralumenal proteins that stain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1be09de20f9e0ff0b076337c7014c75
https://doi.org/10.1016/s0021-9258(18)53868-0
https://doi.org/10.1016/s0021-9258(18)53868-0
Autor:
Jeffry S. Kelley, Shelley Collins, Lee Ann Lawson, Clive Wasserfall, Barry J. Byrne, Mark A. Atkinson, K. Harfe, Melissa E. Elder, Sushrusha Nayak, L. Falk
Publikováno v:
Molecular Genetics and Metabolism. 102:S31-S32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::078c758f7a2febd958c0a33ef5f87a48
https://doi.org/10.1016/j.ymgme.2010.11.107
https://doi.org/10.1016/j.ymgme.2010.11.107
Autor:
Anthony Stevens, David J. Lockhart, Jeffry S. Kelley, Elfrida R. Benjamin, Farhana Pruthi, Eric Sjoberg, Kenneth J. Valenzano, Evan Katz, Brandon Wustman, M. Cecilia Della Valle, Carrolee Barlow, Nestor Gomez, Barry J. Byrne, Xiaoyang Wu, Sheela Sitaraman
Publikováno v:
Molecular Genetics and Metabolism. 111:S25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3374003b5b71ef1cc9e5e1f3ae7ce85e
https://doi.org/10.1016/j.ymgme.2013.12.038
https://doi.org/10.1016/j.ymgme.2013.12.038