Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Jeffry D. Sander"'
Autor:
Y. Esther Tak, Gaylor Boulay, Lukuo Lee, Sowmya Iyer, Nicholas T. Perry, Hayley T. Schultz, Sara P. Garcia, Liliane Broye, Joy E. Horng, Shruthi Rengarajan, Beverly Naigles, Angela Volorio, Jeffry D. Sander, Jingyi Gong, Nicolò Riggi, J. Keith Joung, Miguel N. Rivera
Publikováno v:
Cell Genomics, Vol 2, Iss 4, Pp 100119- (2022)
Summary: Repeat elements can be dysregulated at a genome-wide scale in human diseases. For example, in Ewing sarcoma, hundreds of inert GGAA repeats can be converted into active enhancers when bound by EWS-FLI1. Here we show that fusions between EWS
Externí odkaz:
https://doaj.org/article/95b2c278cc204064b4d31361085de605
Autor:
Huirong Gao, Jasdeep Mutti, Joshua K. Young, Meizhu Yang, Megan Schroder, Brian Lenderts, Lijuan Wang, Dave Peterson, Grace St. Clair, Spencer Jones, Lanie Feigenbutz, Wally Marsh, Min Zeng, Susan Wagner, Jeffry Farrell, Kay Snopek, Chris Scelonge, Xiaoyi Sopko, Jeffry D. Sander, Scott Betts, A. Mark Cigan, N. Doane Chilcoat
Publikováno v:
Frontiers in Plant Science, Vol 11 (2020)
Modern maize hybrids often contain biotech and native traits. To-date all biotech traits have been randomly inserted in the genome. Consequently, developing hybrids with multiple traits is expensive, time-consuming, and complex. Here we report using
Externí odkaz:
https://doaj.org/article/1e57717eb81b4cd696863de608e3ba39
Autor:
Scott D. Betts, Sutirtha Basu, Joy Bolar, Russ Booth, Shujun Chang, A. Mark Cigan, Jeffry Farrell, Huirong Gao, Kristi Harkins, Anthony Kinney, Brian Lenderts, Zhongsen Li, Lu Liu, Michelle McEnany, Jasdeep Mutti, Dave Peterson, Jeffry D. Sander, Chris Scelonge, Xiaoyi Sopko, Dave Stucker, Emily Wu, N. Doane Chilcoat
Publikováno v:
Frontiers in Plant Science, Vol 10 (2019)
Development of transgenic cell lines or organisms for industrial, agricultural, or medicinal applications involves inserting DNA into the target genome in a way that achieves efficacious transgene expression without a deleterious impact on fitness. T
Externí odkaz:
https://doaj.org/article/d27d6e7e6bea4223b39d97fcf33b1e21
Autor:
Hui-Shan Li, Divya V. Israni, Keith A. Gagnon, Kok Ann Gan, Michael H. Raymond, Jeffry D. Sander, Kole T. Roybal, J. Keith Joung, Wilson W. Wong, Ahmad S. Khalil
Publikováno v:
Science
Synthetic gene circuits that precisely control human cell function could expand the capabilities of gene- and cell-based therapies. However, platforms for developing circuits in primary human cells that drive robust functional changes in vivo and hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce117349f45b5a23bca41469b23a003
https://europepmc.org/articles/PMC10054295/
https://europepmc.org/articles/PMC10054295/
Autor:
Jeffry D. Sander, Sergei Svitashev, Sandeep Kumar, William J. Gordon-Kamm, Pierluigi Barone, Todd J. Jones
Publikováno v:
Genome editing for precision crop breeding ISBN: 9781786764478
Genome editing for precision crop breeding
Genome editing for precision crop breeding
Despite the conspicuous and rapid development of genome editing tools, implementing this technology in plants often remains constrained by our inability to regenerate fertile genome-modified plants. Finding a viable combination of delivery method, ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10487b4c188643c0c9e33be270c5c4c8
https://doi.org/10.4324/9781003048237-9
https://doi.org/10.4324/9781003048237-9
Autor:
Jeffry D. Sander, J. Keith Joung, Divya V. Israni, Kole T. Roybal, Hui-Shan Li, Keith A. Gagnon, Wilson W. Wong, Ahmad S. Khalil
Synthetic biology seeks to enable the rational design of regulatory molecules and circuits to reprogram cellular behavior. The application of this approach to human cells could lead to powerful gene and cell-based therapies that provide transformativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5314f234e4eced1e0989f3ed6fd71d85
https://doi.org/10.1101/2021.02.22.432371
https://doi.org/10.1101/2021.02.22.432371
Autor:
Woong Y Hwang, Yanfang Fu, Deepak Reyon, Morgan L Maeder, Prakriti Kaini, Jeffry D Sander, J Keith Joung, Randall T Peterson, Jing-Ruey Joanna Yeh
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68708 (2013)
We have previously reported a simple and customizable CRISPR (clustered regularly interspaced short palindromic repeats) RNA-guided Cas9 nuclease (RGN) system that can be used to efficiently and robustly introduce somatic indel mutations in endogenou
Externí odkaz:
https://doaj.org/article/ac7dbb56bb564ab4a308baa536e6c2a3
Autor:
Susan Wagner, Min Zeng, Wally Marsh, Joshua K. Young, Huirong Gao, A. Mark Cigan, Scott D. Betts, Lijuan Wang, Spencer Jones, Meizhu Yang, Brian Lenderts, Kay Snopek, Jeffry Farrell, Jasdeep S. Mutti, Xiaoyi Sopko, Lanie Feigenbutz, Dave Peterson, N. Doane Chilcoat, Megan Schroder, Jeffry D. Sander, Grace St. Clair, Christopher J. Scelonge
Publikováno v:
Frontiers in Plant Science, Vol 11 (2020)
Frontiers in Plant Science
Frontiers in Plant Science
Modern maize hybrids often contain biotech and native traits. To-date all biotech traits have been randomly inserted in the genome. Consequently, developing hybrids with multiple traits is expensive, time-consuming, and complex. Here we report using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2320a7beb6205d70366f34bc606c50e0
https://doi.org/10.3389/fpls.2020.00535
https://doi.org/10.3389/fpls.2020.00535
Autor:
Dave Stucker, Kristi Harkins, A. Mark Cigan, Sutirtha Basu, Brian Lenderts, Scott D. Betts, Jeffry D. Sander, Jasdeep S. Mutti, Zhongsen Li, Jeffry Farrell, Joy Bolar, Shujun Chang, Michelle McEnany, Emily Wu, Xiaoyi Sopko, Dave Peterson, Huirong Gao, Russ Booth, Anthony J. Kinney, Christopher J. Scelonge, Lu Liu, N. Doane Chilcoat
Publikováno v:
Frontiers in Plant Science
Frontiers in Plant Science, Vol 10 (2019)
Frontiers in Plant Science, Vol 10 (2019)
Development of transgenic cell lines or organisms for industrial, agricultural, or medicinal applications involves inserting DNA into the target genome in a way that achieves efficacious transgene expression without a deleterious impact on fitness. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c41349b22fc22007862f1ae27f9102a
http://europepmc.org/articles/PMC6821721
http://europepmc.org/articles/PMC6821721
Autor:
Jeffry D, Sander
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1931
The application of CRISPR/Cas to introduce targeted genomic edits is powering research and discovery across the genetic frontier. Applying CRISPR/Cas in sorghum can facilitate the study of gene function and unlock our understanding of this robust cro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::19c9ead75bfac2947d208c061b4bc176
https://pubmed.ncbi.nlm.nih.gov/30652289
https://pubmed.ncbi.nlm.nih.gov/30652289