Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jeffrey van Haren"'
Autor:
Maxime C van Zwam, Anubhav Dhar, Willem Bosman, Wendy van Straaten, Suzanne Weijers, Emiel Seta, Ben Joosten, Jeffrey van Haren, Saravanan Palani, Koen van den Dries
Publikováno v:
PLoS Biology, Vol 22, Iss 3, p e3002551 (2024)
Mammals have 6 highly conserved actin isoforms with nonredundant biological functions. The molecular basis of isoform specificity, however, remains elusive due to a lack of tools. Here, we describe the development of IntAct, an internal tagging strat
Externí odkaz:
https://doaj.org/article/7551166c07cc4412b7038354880bbaf1
Publikováno v:
eLife, Vol 12 (2023)
A challenge in analyzing dynamic intracellular cell biological processes is the dearth of methodologies that are sufficiently fast and specific to perturb intracellular protein activities. We previously developed a light-sensitive variant of the micr
Externí odkaz:
https://doaj.org/article/b460e12d2f484cd7b6513c8f5053e47c
Autor:
Ksenija Drabek, Laura Gutiérrez, Marcel Vermeij, Thomas Clapes, Sunita R. Patel, Jean-Charles Boisset, Jeffrey van Haren, Ana L. Pereira, Zhe Liu, Umut Akinci, Tatjana Nikolic, Wilfred van IJcken, Mirjam van den Hout, Marjolein Meinders, Clara Melo, Clara Sambade, Dubravka Drabek, Rudi W. Hendriks, Sjaak Philipsen, Mieke Mommaas, Frank Grosveld, Helder Maiato, Joseph E. Italiano, Jr., Catherine Robin, Niels Galjart
Publikováno v:
Cell Reports, Vol 2, Iss 4, Pp 781-788 (2012)
Mammalian CLASPs are microtubule plus-end tracking proteins whose essential function as regulators of microtubule behavior has been studied mainly in cultured cells. We show here that absence of murine CLASP2 in vivo results in thrombocytopenia, prog
Externí odkaz:
https://doaj.org/article/3e5cff7148ce447398adad76a986d785
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2430
Micropatterning of extracellular matrix proteins enables defining cell position and shape in experiments investigating intracellular dynamics and organization. While such standardization is advantageous in automated and quantitative analysis of many
Autor:
Adrienne E. D. Stormo, Farbod Shavarebi, Molly FitzGibbon, Elizabeth M. Earley, Hannah Ahrendt, Lotus S. Lum, Erik Verschueren, Danielle L. Swaney, Gaia Skibinski, Abinaya Ravisankar, Jeffrey van Haren, Emily J. Davis, Jeffrey R. Johnson, John Von Dollen, Carson Balen, Jacob Porath, Claudia Crosio, Christian Mirescu, Ciro Iaccarino, William T. Dauer, R. Jeremy Nichols, Torsten Wittmann, Timothy C. Cox, Steve Finkbeiner, Nevan J. Krogan, Scott A. Oakes, Annie Hiniker
Publikováno v:
Journal of Cell Biology, 221(4):e202010065. Rockefeller University Press
The Journal of cell biology, vol 221, iss 4
The Journal of cell biology, vol 221, iss 4
Missense mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of familial Parkinson’s Disease (PD); however, pathways regulating LRRK2 subcellular localization, function, and turnover are not fully defined. We performed quant
Publikováno v:
Current Opinion in Cell Biology, 66, 1-10. Elsevier Ltd.
Curr Opin Cell Biol
Curr Opin Cell Biol
Cell biology is moving from observing molecules to controlling them in real time, a critical step towards a mechanistic understanding of how cells work. Initially developed from light-gated ion channels to control neuron activity, optogenetics now de
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619827
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ba339f46ae41089308647be43163f52
https://doi.org/10.1007/978-1-0716-1983-4_29
https://doi.org/10.1007/978-1-0716-1983-4_29
Autor:
Christine Fagotto-Kaufmann, Anne Debant, Amandine Falco, Freddy Jeanneteau, Marion Bonhomme, Jérôme Boudeau, Niels Galjart, Jeffrey van Haren, Carlos Sánchez-Huertas
Publikováno v:
Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2020, 219 (9), ⟨10.1083/jcb.201905199⟩
The Journal of Cell Biology
Digital.CSIC. Repositorio Institucional del CSIC
instname
Journal of Cell Biology, 219(9):e201905199. Rockefeller University Press
Journal of Cell Biology, Rockefeller University Press, 2020, 219 (9), ⟨10.1083/jcb.201905199⟩
The Journal of Cell Biology
Digital.CSIC. Repositorio Institucional del CSIC
instname
Journal of Cell Biology, 219(9):e201905199. Rockefeller University Press
Trabajo presentado al 17th Meeting of the Spanish Society for Developmental Biology (SEBD), celebrado de forma virtual del 18 al 20 de noviembre de 2020.
The microtubule plus-end tracking proteins (+TIPs) are central players in the coordination
The microtubule plus-end tracking proteins (+TIPs) are central players in the coordination
Autor:
Torsten Wittmann, Rabab A. Charafeddine, Klaus M. Hahn, Jeffrey van Haren, Andreas Ettinger, Hui Wang
Publikováno v:
Nat. Cell Biol. 20, 252–261 (2018)
Nature cell biology, vol 20, iss 3
Nature cell biology
Nature cell biology, vol 20, iss 3
Nature cell biology
End-binding proteins (EBs) are adaptors that recruit functionally diverse microtubule plus-end-tracking proteins (+TIPs) to growing microtubule plus ends. To test with high spatial and temporal accuracy how, when and where + TIP complexes contribute