Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jeffrey Y. Lee"'
Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells
Autor:
Peter A.C. Wing, Thomas P. Keeley, Xiaodong Zhuang, Jeffrey Y. Lee, Maria Prange-Barczynska, Senko Tsukuda, Sophie B. Morgan, Adam C. Harding, Isobel L.A. Argles, Samvid Kurlekar, Marko Noerenberg, Craig P. Thompson, Kuan-Ying A. Huang, Peter Balfe, Koichi Watashi, Alfredo Castello, Timothy S.C. Hinks, William James, Peter J. Ratcliffe, Ilan Davis, Emma J. Hodson, Tammie Bishop, Jane A. McKeating
Publikováno v:
Cell Reports, Vol 35, Iss 3, Pp 109020- (2021)
Summary: COVID-19, caused by the novel coronavirus SARS-CoV-2, is a global health issue with more than 2 million fatalities to date. Viral replication is shaped by the cellular microenvironment, and one important factor to consider is oxygen tension,
Externí odkaz:
https://doaj.org/article/0e81e8390d8b4bff8a888f023b7b0038
Autor:
Tamsin J. Samuels, Yoav Arava, Aino I. Järvelin, Francesca Robertson, Jeffrey Y. Lee, Lu Yang, Ching-Po Yang, Tzumin Lee, David Ish-Horowicz, Ilan Davis
Publikováno v:
Biology Open, Vol 9, Iss 5 (2020)
During Drosophila and vertebrate brain development, the conserved transcription factor Prospero/Prox1 is an important regulator of the transition between proliferation and differentiation. Prospero level is low in neural stem cells and their immediat
Externí odkaz:
https://doaj.org/article/111c245f4fda40cb8f0d79a59b779481
Autor:
Jeffrey Y Lee, Peter AC Wing, Dalia S Gala, Marko Noerenberg, Aino I Järvelin, Joshua Titlow, Xiaodong Zhuang, Natasha Palmalux, Louisa Iselin, Mary Kay Thompson, Richard M Parton, Maria Prange-Barczynska, Alan Wainman, Francisco J Salguero, Tammie Bishop, Daniel Agranoff, William James, Alfredo Castello, Jane A McKeating, Ilan Davis
Publikováno v:
eLife, Vol 11 (2022)
Despite an unprecedented global research effort on SARS-CoV-2, early replication events remain poorly understood. Given the clinical importance of emergent viral variants with increased transmission, there is an urgent need to understand the early st
Externí odkaz:
https://doaj.org/article/9faa31e3a35e4bed8c3ceedffa1e3c5f
Autor:
Dalia S. Gala, Jeffrey Y. Lee, Maria Kiourlappou, Joshua S. Titlow, Rita O. Teodoro, Ilan Davis
SUMMARYThe polarization of cells often involves the transport of specific mRNAs and their localized translation in distal projections. Neurons and glia both contain long cytoplasmic processes with important functions. mRNA localization has been studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87a0a2c821e5a10093fd92aee3aa2a50
https://doi.org/10.1101/2022.11.30.518536
https://doi.org/10.1101/2022.11.30.518536
Autor:
Ilan Davis, Stephen Taylor, Richard M Parton, Ilias Kounatidis, Mary Kay Thompson, Aino I Järvelin, Diana Arman, Staci Thornton, Alex Dallman-Porter, Hugh Mulvey, Finn Strivens, Helena S Francis, Sam Garforth, David Miguel Susano Pinto, Florence L Young, Joyce J S Yu, Darragh Ennis, Dalia S Gala, Jeffrey Y Lee, Ana Palanca, Maria Kiourlappou, Joshua S Titlow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe45f4f48e580480acf4aef36d18034f
https://doi.org/10.15252/rc.2022705875
https://doi.org/10.15252/rc.2022705875
Autor:
Joshua S Titlow, Maria Kiourlappou, Ana Palanca, Jeffrey Y Lee, Dalia S Gala, Darragh Ennis, Joyce J S Yu, Florence L Young, David Miguel Susano Pinto, Sam Garforth, Helena S Francis, Finn Strivens, Hugh Mulvey, Alex Dallman-Porter, Staci Thornton, Diana Arman, Aino I Järvelin, Mary Kay Thompson, Ilias Kounatidis, Richard M Parton, Stephen Taylor, Ilan Davis
SummaryWhile post-transcriptional control is thought to be required at the periphery of neurons and glia, its extent is unclear. Here, we investigate systematically the spatial distribution and expression of mRNA at single molecule sensitivity and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d33fc79b55cf104fee60fb1c19c05c1b
https://doi.org/10.1101/2022.03.21.485142
https://doi.org/10.1101/2022.03.21.485142
Autor:
Peter AC Wing, Jeffrey Y Lee, Dalia S Gala, Marko Noerenberg, Aino I Järvelin, Joshua Titlow, Xiaodong Zhuang, Natasha Palmalux, Louisa Iselin, Mary Kay Thompson, Richard M Parton, Maria Prange-Barczynska, Alan Wainman, Francisco J Salguero, Tammie Bishop, Daniel Agranoff, William James, Alfredo Castello, Jane A McKeating, Ilan Davis
Publikováno v:
eLife, Vol 11 (2022)
Despite an unprecedented global research effort on SARS-CoV-2, early replication events remain poorly understood. Given the clinical importance of emergent viral variants with increased transmission, there is an urgent need to understand the early st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f83d2c06db6d8990167652952f2eff4
https://eprints.gla.ac.uk/261282/1/261282.pdf
https://eprints.gla.ac.uk/261282/1/261282.pdf
Autor:
Mar Puigdellívol, Stefan Milde, Anna Vilalta, Tom O.J. Cockram, David H. Allendorf, Jeffrey Y. Lee, Jacob M. Dundee, Katryna Pampuščenko, Vilmante Borutaite, Hugh N. Nuthall, Jack H. Brelstaff, Maria Grazia Spillantini, Guy C. Brown
Publikováno v:
Cell Reports
Summary Microglia are implicated in neurodegeneration, potentially by phagocytosing neurons, but it is unclear how to block the detrimental effects of microglia while preserving their beneficial roles. The microglial P2Y6 receptor (P2Y6R) – activat
Autor:
Peter AC Wing, Jeffrey Y Lee, Dalia S Gala, Marko Noerenberg, Aino I Järvelin, Joshua Titlow, Xiaodong Zhuang, Natasha Palmalux, Louisa Iselin, Mary Kay Thompson, Richard M Parton, Maria Prange-Barczynska, Alan Wainman, Francisco J Salguero, Tammie Bishop, Daniel Agranoff, William James, Alfredo Castello, Jane A McKeating, Ilan Davis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2310bc79cbe7663ef121700a9200ace1
https://doi.org/10.7554/elife.74153.sa2
https://doi.org/10.7554/elife.74153.sa2
Autor:
Louisa Iselin, Alan Wainman, Richard M. Parton, Jane A. McKeating, Marko Noerenberg, Mary Kay Thompson, Alfredo Castello, William James, Ilan Davis, Aino I. Järvelin, Daniel Agranoff, Natasha Palmalux, Dalia Gala, Jeffrey Y. Lee, Josh Titlow, Peter A C Wing, Xiaodong Zhuang
SummaryDespite an unprecedented global research effort on SARS-CoV-2, early replication events remain poorly understood. Given the clinical importance of emergent viral variants with increased transmission, there is an urgent need to understand the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90c9c0ea5d984a6e3e1055ee23dbf95d
https://doi.org/10.1101/2021.06.29.450133
https://doi.org/10.1101/2021.06.29.450133