Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jeffrey Y. Lai"'
Autor:
Naima G Sharaf, Mona Shahgholi, Esther Kim, Jeffrey Y Lai, David G VanderVelde, Allen T Lee, Douglas C Rees
Publikováno v:
eLife, Vol 10 (2021)
NmMetQ is a substrate-binding protein (SBP) from Neisseria meningitidis that has been identified as a surface-exposed candidate antigen for meningococcal vaccines. However, this location for NmMetQ challenges the prevailing view that SBPs in Gram-neg
Externí odkaz:
https://doaj.org/article/644cf02d64a6410194394509bed6ace7
Autor:
Esther Kim, Allen T. Lee, Douglas C. Rees, Jeffrey Y. Lai, Mona Shahgholi, David G. VanderVelde, Naima G. Sharaf
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
NmMetQ is a substrate-binding protein (SBP) from Neisseria meningitidis that has been identified as a surface-exposed candidate antigen for meningococcal vaccines. However, this location for NmMetQ challenges the prevailing view that SBPs in Gram-neg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e884c1a27f9a7f49ee8cf798c5197eef
https://elifesciences.org/articles/69742
https://elifesciences.org/articles/69742
Publikováno v:
Protein Science : A Publication of the Protein Society
The bacterial periplasmic methionine‐binding protein MetQ is involved in the import of methionine by the cognate MetNI methionine ATP binding cassette (ABC) transporter. The MetNIQ system is one of the few members of the ABC importer family that ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc7ab09ae447f6b475c4f43d296f524
https://doi.org/10.1002/pro.3694
https://doi.org/10.1002/pro.3694
Autor:
Allen T. Lee, Esther Kim, Naima G. Sharaf, Mona Shahgholi, David G. VanderVelde, Jeffrey Y. Lai, Douglas C. Rees
NmMetQ is a substrate binding protein (SBP) from Neisseria meningitidis that has been identified as a surface-exposed candidate antigen for meningococcal vaccines. However, this location for NmMetQ challenges the prevailing view that SBPs in Gram-neg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b56850fbd90401cd88999e87f91fb33
https://doi.org/10.1101/2021.05.04.442564
https://doi.org/10.1101/2021.05.04.442564
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The high-affinity methionine importer MetNI belongs to the ATP Binding Cassette (ABC) family of transporters that carry out the ATP-dependent uptake of substrates into cells. As with other ABC importers, MetNI requires a soluble binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::497d74e0820c5146a2c58970fde6a4d5
https://doi.org/10.1073/pnas.1811003115
https://doi.org/10.1073/pnas.1811003115
Autor:
Michael H. B. Stowell, Keeshia Wang, Tamara Basta, Jonas Lee, John M. Heumann, Yung-Cheng Lee, Douglas C. Rees, Mary K. Morphew, Hsin-Jui Wu, Jeffrey Y. Lai, Nilanjan Ghosh
Publikováno v:
Proceedings of the National Academy of Sciences. 111:670-674
We demonstrate that membrane proteins and phospholipids can self-assemble into polyhedral arrangements suitable for structural analysis. Using the Escherichia coli mechanosensitive channel of small conductance (MscS) as a model protein, we prepared m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31ba2f13693d4a2477c14d4b7bb66701
https://doi.org/10.1073/pnas.1321936111
https://doi.org/10.1073/pnas.1321936111
Publikováno v:
Protein Science. 22:502-509
The mechanosensitive channel of small conductance (MscS) contributes to the survival of bacteria during osmotic downshock by transiently opening large diameter pores for the efflux of cellular contents before the membrane ruptures. Two crystal struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::593a228493faaf64e9ec078fb3590b64
https://doi.org/10.1002/pro.2222
https://doi.org/10.1002/pro.2222
Publikováno v:
Biological chemistry. 396(9-10)
Despite the ubiquitous role of ATP-binding cassette (ABC) importers in nutrient uptake, only the Escherichia coli maltose and vitamin B12 ABC transporters have been structurally characterized in multiple conformations relevant to the alternating acce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d19e1cc9dbc332ef44b5e75642de5e68
https://pubmed.ncbi.nlm.nih.gov/25803078
https://pubmed.ncbi.nlm.nih.gov/25803078