Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jeffrey X, Xie"'
Autor:
Jeffrey X. Xie, Helen Alderson, James Ritchie, Philip A. Kalra, Yanmei Xie, Kaili Ren, Hanh Nguyen, Tian Chen, Pamela Brewster, Rajesh Gupta, Lance D. Dworkin, Deepak Malhotra, Christopher J. Cooper, Jiang Tian, Steven T. Haller
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Abstract Soluble CD40 ligand (sCD40L) has been implicated in the development of renal injury. The CD40 receptor exists in a soluble form, sCD40R, and has been shown to function as a competitive antagonist against CD40 activation. We analyzed whether
Externí odkaz:
https://doaj.org/article/48f5f24ffe304226aa5bceacf2bedcf1
Autor:
Gustavo Blanco, Jeffrey X. Xie, Jiayan Wang, Kayleigh C Terrell, Liquan Cai, Sandrine V. Pierre, Zijian Xie, Hua Zhu, Shreya Tapan Mukherji, Minqi Huang, Adam J Martin, Xiaoyu Cui, Judith A. Heiny, Xiaoliang Wang, Marco T Pessoa, Laura C Kutz, Joseph I. Shapiro
Publikováno v:
Acta physiologica (Oxford, England). 232(3)
Aim Highly prevalent diseases such as insulin resistance and heart failure are characterized by reduced metabolic flexibility and reserve. We tested whether Na/K-ATPase (NKA)-mediated regulation of Src kinase, which requires two NKA sequences specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::102b40445737ab81b28a28ef0c9d36dd
https://pubmed.ncbi.nlm.nih.gov/33991391
https://pubmed.ncbi.nlm.nih.gov/33991391
Autor:
Pauline V, Marck, Marco T, Pessoa, Yunhui, Xu, Laura C, Kutz, Dominic M, Collins, Yanling, Yan, Cierra, King, Xiaoliang, Wang, Qiming, Duan, Liquan, Cai, Jeffrey X, Xie, Jerry B, Lingrel, Zijian, Xie, Jiang, Tian, Sandrine V, Pierre
Publikováno v:
International Journal of Molecular Sciences
The Na/K-ATPase is the specific receptor for cardiotonic steroids (CTS) such as ouabain and digoxin. At pharmacological concentrations used in the treatment of cardiac conditions, CTS inhibit the ion-pumping function of Na/K-ATPase. At much lower con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::04f6c5346e534cc70353b2235be7beb1
https://pubmed.ncbi.nlm.nih.gov/33801629
https://pubmed.ncbi.nlm.nih.gov/33801629
Autor:
Pauline V Marck, Zijian Xie, Liquan Cai, Tong Wang, Yunhui Xu, Joseph I. Shapiro, Jeffrey X. Xie, Feng Feng, Minqi Huang
Publikováno v:
Mol Pharmacol
Recent studies have revealed that Na/K-ATPase (NKA) can transmit signals through ion-pumping–independent activation of pathways relayed by distinct intracellular protein/lipid kinases, and endocytosis challenges the traditional definition that card
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee94b363fe77b2ea97f4131cee3e171c
https://pubmed.ncbi.nlm.nih.gov/33495275
https://pubmed.ncbi.nlm.nih.gov/33495275
Autor:
Yiliang Chen, Joseph I. Shapiro, Dianqing Wu, Xiaoliang Wang, Xiaoyu Cui, Liquan Cai, Jue Zhang, Jiayan Wang, Jeffrey X. Xie, Guo-Zhang Zhu, Isabel Larre, Zijian Xie, Sandrine V. Pierre
Publikováno v:
Science Advances
Caveolin binding motif of Na/K-ATPase is essential for mammals and C. elegans organogenesis.
Several signaling events have been recognized as essential for regulating cell lineage specification and organogenesis in animals. We find that the gain
Several signaling events have been recognized as essential for regulating cell lineage specification and organogenesis in animals. We find that the gain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76788e19f2f914ae2f97721b326f4000
http://europepmc.org/articles/PMC7253156
http://europepmc.org/articles/PMC7253156
Autor:
David J Kennedy, Jue Zhang, Hui Yu, Jeffrey X. Xie, Jiang Tian, Xiaoyu Cui, Joseph I. Shapiro, Steven T. Haller, Shungang Zhang, Deepak Malhotra, Fatimah K Khalaf
Publikováno v:
Nephrology Dialysis Transplantation. 33:1138-1149
Background Recent studies have highlighted a critical role for CD40 in the pathogenesis of renal injury and fibrosis. However, little is currently understood about the regulation of CD40 in this setting. Methods We use novel Na/K-ATPase cell lines an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c021be3748971d143effa5f0f090c203
https://doi.org/10.1093/ndt/gfx334
https://doi.org/10.1093/ndt/gfx334
Autor:
Jeffrey X. Xie, Reetam Majumder, Xiaoming Fan, Christopher J. Cooper, Yanmei Xie, Lijun Liu, Pamela S. Brewster, Christopher A. Drummond, Steven T. Haller, Lance D. Dworkin, Jiang Tian, Tian Chen
Publikováno v:
Gene. 627:1-8
Liquid biopsies have advanced rapidly in recent years for use in diagnostic and prognostic applications. One important aspect of this advancement is the growth in our understanding of microRNA (miRNA) biology. The measurement of miRNAs packaged withi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::908d7e8480a41780d5df8872a19cdc80
https://doi.org/10.1016/j.gene.2017.06.003
https://doi.org/10.1016/j.gene.2017.06.003
Autor:
Yanling Yan, Yunhui Xu, Cierra King, Zijian Xie, Jiang Tian, Laura C Kutz, Qiming Duan, Xiaoliang Wang, Sandrine V. Pierre, Pauline V Marck, Liquan Cai, Jerry B. Lingrel, Marco T Pessoa, Dominic M Collins, Jeffrey X. Xie
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 7
International Journal of Molecular Sciences, Vol 22, Iss 3462, p 3462 (2021)
Volume 22
Issue 7
International Journal of Molecular Sciences, Vol 22, Iss 3462, p 3462 (2021)
The Na/K-ATPase is the specific receptor for cardiotonic steroids (CTS) such as ouabain and digoxin. At pharmacological concentrations used in the treatment of cardiac conditions, CTS inhibit the ion-pumping function of Na/K-ATPase. At much lower con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc889459bb7b102d6fa86775b2da75f
https://doi.org/10.3390/ijms22073462
https://doi.org/10.3390/ijms22073462
Autor:
Steven T. Haller, Jiang Tian, Denzil P. Mathew, Joseph I. Shapiro, Jeffrey X. Xie, Yanling Yan, Christopher J. Cooper, Christopher A. Drummond, Xiaoming Fan, Dawn-Alita Hernandez, Laura E. Crotty Alexander, Jiang Liu, David J. Kennedy
Publikováno v:
Physiological Genomics. 48:950-960
Clinical studies indicate that smoking combustible cigarettes promotes progression of renal and cardiac injury, leading to functional decline in the setting of chronic kidney disease (CKD). However, basic studies using in vivo small animal models tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abde567713fe0950e660c9d32648fcb1
https://doi.org/10.1152/physiolgenomics.00070.2016
https://doi.org/10.1152/physiolgenomics.00070.2016
Autor:
Steven T. Haller, Jeffrey X. Xie, Michael C. Hill, Christopher J. Cooper, Jiang Liu, Joseph I. Shapiro, Jiang Tian, Huilin Shi, Zijian Xie, David J. Kennedy, Christopher A. Drummond, Xiaoming Fan, Michael R. Garrett
Publikováno v:
Physiological Genomics. 48:220-229
Chronic kidney disease (CKD) is accompanied by cardiac fibrosis, hypertrophy, and dysfunction, which are commonly referred to as uremic cardiomyopathy. Our previous studies found that Na/K-ATPase ligands or 5/6th partial nephrectomy (PNx) induces car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3d8d6e0d6a77acc89ec0476d9a5293a
https://doi.org/10.1152/physiolgenomics.00116.2015
https://doi.org/10.1152/physiolgenomics.00116.2015