Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Jeffrey W. Skimming"'
Publikováno v:
Vascular Pharmacology. 43:404-410
We recently demonstrated that lipoic acid suppresses endotoxin-stimulated expression of inducible nitric oxide synthase and nitric oxide production in mouse macrophages. In this study, we tested whether lipoic acid suppresses these inflammatory media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eacfc29eaf3d9dbdc9afb199088d4990
https://doi.org/10.1016/j.vph.2005.08.005
https://doi.org/10.1016/j.vph.2005.08.005
Publikováno v:
Human Molecular Genetics. 13:1669-1675
Gene therapy holds great promise for curing Duchenne muscular dystrophy (DMD), the most common fatal inherited childhood muscle disease. Success of DMD gene therapy depends upon functional improvement in both skeletal and cardiac muscle. Numerous gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbaad0828f4909a04042289ed5021617
https://doi.org/10.1093/hmg/ddh174
https://doi.org/10.1093/hmg/ddh174
Publikováno v:
Free Radical Research. 38:675-682
The heat shock response protects against sepsis-induced mortality, organ injury, cardiovascular dysfunction, and apoptosis. Several inducers of the heat shock response, such as hyperthermia, sodium arsenite, and pyrollidine dithiocarbonate, inhibit N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e49df0eab627987e482c0fd08803970
https://doi.org/10.1080/10715760410001702503
https://doi.org/10.1080/10715760410001702503
Autor:
Jeffrey W. Skimming, Paul J. Sarcia, Bruce R. Stevens, Charles E. Wood, Philip O. Scumpia, Ikram U. Haque, Omer Nasiroglu, Chun-Jen Huang
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 285:L484-L491
The in vivo mechanisms by which glucocorticoids inhibit nitric oxide expression await detailed investigation. In cell culture experiments, glucocorticoids have been shown to inhibit inducible nitric oxide synthase (iNOS) formation and activity. Gluco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41619a4174b9b756dd9a1ff495bc41de
https://doi.org/10.1152/ajplung.00433.2002
https://doi.org/10.1152/ajplung.00433.2002
Publikováno v:
Shock. 20:41-45
We recently reported that hypothermia protects against intrapulmonary nitric oxide overproduction and nitric oxide-mediated lung injury in endotoxemic rats. Few studies have been performed to investigate whether hypothermia reduces inflammation by af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b310bfbfb57f120ea6721adc773b8b
https://doi.org/10.1097/01.shk.0000071080.50028.f2
https://doi.org/10.1097/01.shk.0000071080.50028.f2
Autor:
Jeffrey W. Skimming, Xiaoying Fang, Charles E. Wood, Chun-Jen Huang, Paul N Slovin, Omer Nasiroglu
Publikováno v:
Resuscitation. 55:201-209
Hemorrhagic shock has been shown to upregulate intrapulmonary inducible nitric oxide (NO) synthase (iNOS) expression. Increased intrapulmonary iNOS expression is reflected by increases in concentrations of NO in the airways. The purpose of this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0559afa97bdc2c685efa8b94b24eadf1
https://doi.org/10.1016/s0300-9572(02)00158-2
https://doi.org/10.1016/s0300-9572(02)00158-2
Publikováno v:
Intensive Care Medicine. 28:1145-1150
Objective. Excess nitric oxide (NO) and its reactive derivatives cause oxidative reactions that lead to cell death. Propofol, an intravenous anesthetic, exhibits antioxidant properties. Diprivan is a widely used commercial preparation of propofol tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b597530f76da63dc16eb37120ab09f0
https://doi.org/10.1007/s00134-002-1380-9
https://doi.org/10.1007/s00134-002-1380-9
Autor:
Jeffrey W. Skimming, J. Robert Cade, Charles E. Wood, Omer Nasiroglu, Malcolm Privette, Chun-Jen Huang, Paul N Slovin, Pini Orbach
Publikováno v:
Resuscitation. 50:109-115
Pyruvate is an energy substrate that has both inotropic and antioxidant properties. In this study, we tested the hypothesis that survivorship would be better after resuscitation with 1.7% sodium pyruvate than 0.9% sodium chloride in a profound hemorr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e50cfc68409cc822c75602bee7bf3d
https://doi.org/10.1016/s0300-9572(01)00325-2
https://doi.org/10.1016/s0300-9572(01)00325-2
Autor:
Jeffrey W. Skimming, H.K. Spalding, David J. Burchfield, M J Jaeger, Michael J. Banner, Paul W. Davenport
Publikováno v:
Critical Care Medicine. 29:1195-1200
Objective: To test the hypothesis that nitric oxide inhalation facilitates CO 2 elimination by decreasing alveolar deadspace in an ovine model of acute lung injury. Design: Prospective, placebo-controlled, randomized, crossover model. Setting: Univer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0331ee28b3676843c0928f5764c3cdd
https://doi.org/10.1097/00003246-200106000-00022
https://doi.org/10.1097/00003246-200106000-00022
Autor:
Jeffrey W. Skimming
Publikováno v:
Current Problems in Pediatrics. 28:253-264
Binding of NO to heavy metal-containing proteins probably accounts for many of its physiologic actions. NO inhalation is a promising new treatment for various disorders of neonates. The therapy is most likely to benefit premature neonates who are hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ead476320668f932bbc588659eb6dce
https://doi.org/10.1016/s0045-9380(98)80011-x
https://doi.org/10.1016/s0045-9380(98)80011-x