Výsledky vyhledávání - "Jeffrey W. Habig"

Food safety evaluation for R-proteins introduced by biotechnology: A case study of VNT1 in late blight protected potatoes

Autor: Cathy X. Zhong, Matthew G. Pence, Aaron Rowland, Jeffrey W. Habig

Publikováno v: Regulatory Toxicology and Pharmacology. 95:66-74

Resistance genes (R-genes) from wild potato species confer protection against disease and can be introduced into cultivated potato varieties using breeding or biotechnology. The R-gene, Rpi-vnt1, which encodes the VNT1 protein, protects against late

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82abe32b7449e8da71597574c176721a
https://doi.org/10.1016/j.yrtph.2018.03.008

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Akademický článek

In C. elegans, high levels of dsRNA allow RNAi in the absence of RDE-4.

Autor: Jeffrey W Habig, P Joseph Aruscavage, Brenda L Bass

Publikováno v: PLoS ONE, Vol 3, Iss 12, p e4052 (2008)

C. elegans Dicer requires an accessory double-stranded RNA binding protein, RDE-4, to enact the first step of RNA interference, the cleavage of dsRNA to produce siRNA. While RDE-4 is typically essential for RNAi, we report that in the presence of hig

Externí odkaz: https://doaj.org/article/0606cd392dd5475499f7ff2330d8ae19

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Genes misregulated in C. elegans deficient in Dicer, RDE-4, or RDE-1 are enriched for innate immunity genes

Autor: Noah C. Welker, Jeffrey W. Habig, Brenda L. Bass

Publikováno v: RNA. 13:1090-1102

We describe the first microarray analysis of a whole animal containing a mutation in the Dicer gene. We used adult Caenorhabditis elegans and, to distinguish among different roles of Dicer, we also performed microarray analyses of animals with mutati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3934732864a43938e3c76fc49b8fc05f
https://doi.org/10.1261/rna.542107

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The Conformation of the 3′ End of the Minus-Strand DNA Makes Multiple Contributions to Template Switches during Plus-Strand DNA Synthesis of Duck Hepatitis B Virus

Autor: Jeffrey W. Habig, Daniel D. Loeb

Publikováno v: Journal of Virology. 77:12401-12411

Two template switches are necessary during plus-strand DNA synthesis of the relaxed circular (RC) form of the hepadnavirus genome. The 3′ end of the minus-strand DNA makes important contributions to both of these template switches. It acts as the d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28776c25e715b5866908498a666432c
https://doi.org/10.1128/jvi.77.23.12401-12411.2003

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Small DNA Hairpin Negatively Regulates In Situ Priming during Duck Hepatitis B Virus Reverse Transcription

Autor: Jeffrey W. Habig, Daniel D. Loeb

Publikováno v: Journal of Virology. 76:980-989

There are two mutually exclusive pathways for plus-strand DNA synthesis in hepadnavirus reverse transcription. The predominant pathway gives rise to relaxed circular DNA, while the other pathway yields duplex linear DNA. Both pathways use the same RN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66a490e5bb9ce7427f80a52656baed88
https://doi.org/10.1128/jvi.76.3.980-989.2002

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Improved extraction and complete mass spectral characterization of steroidal alkaloids from Veratrum californicum

Autor: Christopher M, Chandler, Jeffrey W, Habig, Ashley A, Fisher, Katherine V, Ambrose, Susana T, Jiménez, Owen M, McDougal

Publikováno v: Natural product communications. 8(8)

Four steroidal alkaloids extracted from the roots and rhizomes of Veratrum californicum were separated by high performance liquid chromatography (HPLC) and identified using high resolution electrospray ionization time of flight tandem mass spectromet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8728f10f80001a7b8fd6c555543243af
https://pubmed.ncbi.nlm.nih.gov/24079166

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Identification of an amino-terminal fragment of apolipoprotein E4 that localizes to neurofibrillary tangles of the Alzheimer's disease brain

Autor: Jeffrey W. Habig, Kendra G. Coonse, Lindsey W. Catlin, Troy T. Rohn

Publikováno v: Brain research. 1475

Although the risk factor for harboring the apolipoprotein E4 (apoE4) allele in late-onset Alzheimer's disease (AD) is well known, the mechanism by which apoE4 contributes to AD pathogenesis has yet to be clarified. Preferential cleavage of the ApoE4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a1cc32b431b02bbbc0ac4e1770602a0
https://pubmed.ncbi.nlm.nih.gov/22902767

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In C. elegans, high levels of dsRNA allow RNAi in the absence of RDE-4

Autor: Brenda L. Bass, P. Joseph Aruscavage, Jeffrey W. Habig

Publikováno v: PLoS ONE
PLoS ONE, Vol 3, Iss 12, p e4052 (2008)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be38e5898546d0e644ea3b749df7c7e
https://pubmed.ncbi.nlm.nih.gov/19112503

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miRNA editing--we should have inosine this coming

Autor: Taraka Dale, Jeffrey W. Habig, Brenda L. Bass

Publikováno v: Molecular cell. 25(6)

The most prevalent type of RNA editing is mediated by ADAR (adenosine deaminase acting on RNA) enzymes, which convert adenosines to inosines (a process known as A→I RNA editing) in double-stranded (ds)RNA substrates. A→I RNA editing was long thou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d983a57185f5f68b1e8e95b450bfd6d
https://pubmed.ncbi.nlm.nih.gov/17139332

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