Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Jeffrey W. Almond"'
Autor:
Nicholas Glanville, Gary R McLean, Bruno Guy, Valerie Lecouturier, Catherine Berry, Yves Girerd, Christophe Gregoire, Ross P Walton, Rebecca M Pearson, Tatiana Kebadze, Nicolas Burdin, Nathan W Bartlett, Jeffrey W Almond, Sebastian L Johnston
Publikováno v:
PLoS Pathogens, Vol 9, Iss 9, p e1003669 (2013)
Human rhinovirus (RV) infections are the principle cause of common colds and precipitate asthma and COPD exacerbations. There is currently no RV vaccine, largely due to the existence of ∼150 strains. We aimed to define highly conserved areas of the
Externí odkaz:
https://doaj.org/article/07717b4341ab44fc8f7b80ae6c35376c
Autor:
Ghazi Auda, Minor Philip David, Jeffrey W. Almond, Sarah Knowlson, Janet Meredith, David M. Stone, Geraldine Ferguson, Andrew Joseph Macadam
Publikováno v:
Journal of Virology. 80:8653-8663
The global eradication of poliomyelitis caused by wild-type virus is likely to be completed within the next few years, despite immense logistic and political difficulties, and may ultimately be followed by the cessation of vaccination. However, the e
Publikováno v:
British Medical Bulletin
There is currently intense research activity aimed at the development of new delivery systems for vaccines. The goal is to identify optimal methods for presenting target antigens to the immune system in a manner that will elicit immune responses appr
Autor:
Jeffrey W. Almond, Yasmin Chaudhry, Wendy S. Barclay, Janet Meredith, Andrew Richardson, David J.A. Evans, Ian Goodfellow
Publikováno v:
University of St Andrews CRIS
Poliovirus, the archetypal picornavirus, is arguably one of the best characterized of all viruses. The availability of infectious molecular clones (33) has enabled the application of reverse genetics to understand the function of the nonstructural pr
Publikováno v:
Journal of General Virology. 80:3145-3152
Decay accelerating factor (DAF) functions as a cell attachment receptor for a wide range of human enteroviruses, the interaction accounting for the haemagglutination phenotype exhibited by many members of this family. Haemagglutination inhibition ass
Publikováno v:
Journal of Virology. 73:9952-9958
We showed previously that a human rhinovirus 14 (HRV14) 3′ untranslated region (3′ UTR) on a poliovirus genome was able to replicate with nearly wild-type kinetics (J. B. Rohll, D. H. Moon, D. J. Evans, and J. W. Almond, J. Virol 69:7835–7844,
Publikováno v:
Journal of General Virology. 79:1715-1723
The presence of cellular factors that bind to the 3' untranslated region (UTR) of picornaviruses was investigated by electrophoretic mobility shift assays (EMSAs). A cellular factor(s) that binds specifically the 3' UTR of polio-, coxsackie- and rhin
Autor:
Robert M. Powell, Jeffrey W. Almond, Trevor Ward, Pamela A. Pipkin, David J.A. Evans, Phillip D. Minor
Publikováno v:
University of St Andrews CRIS
Echoviruses (EVs) are members of the Enterovirus genus of the family Picornaviridae and are important human pathogens. They are associated with a wide spectrum of clinical syndromes, including rashes, diarrhea, aseptic meningitis, respiratory disease
Autor:
Ian Goodfellow, V Schmitt, David J.A. Evans, Robert M. Powell, Jeffrey W. Almond, Trevor Ward
Publikováno v:
University of St Andrews CRIS
Europe PubMed Central
Europe PubMed Central
Several echoviruses (EVs) have previously been shown to use decay accelerating factor (DAF) as a cellular receptor. Since DAF is expressed on erythrocytes, EVs that use this receptor cause haemagglutination. Here we show that all EVs that haemaggluti
Autor:
David J.A. Evans, Jeffrey W. Almond
Publikováno v:
Trends in Microbiology. 6:198-202
Recent studies have identified at least nine distinct receptors used by the piconaviruses for cell entry. Does the evolution of receptor usage correlate with the different tropisms observed in this group of viruses, and does this influence pathogenes