Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Jeffrey W. Allen"'
Oncofetal Chondroitin Sulfate Is a Highly Expressed Therapeutic Target in Non-Small Cell Lung Cancer
Autor:
Htoo Zarni Oo, Zoltan Lohinai, Nastaran Khazamipour, Joey Lo, Gunjan Kumar, Jessica Pihl, Hans Adomat, Noushin Nabavi, Hakhamanesh Behmanesh, Beibei Zhai, Robert Dagil, Swati Choudhary, Tobias Gustavsson, Thomas M. Clausen, Jeffrey D. Esko, Jeffrey W. Allen, Michael A. Thompson, Nhan L. Tran, Judit Moldvay, Balazs Dome, Ali Salanti, Nader Al-Nakouzi, Glen J. Weiss, Mads Daugaard
Publikováno v:
Cancers, Vol 13, Iss 17, p 4489 (2021)
Broad-spectrum therapeutics in non-small cell lung cancer (NSCLC) are in demand. Most human solid tumors express proteoglycans modified with distinct oncofetal chondroitin sulfate (CS) chains that can be detected and targeted with recombinant VAR2CSA
Externí odkaz:
https://doaj.org/article/53bdcac7991a4b849db695f66547e9e1
Autor:
Jasgit C. Sachdev, Jessica N. Snider, Jeffrey W. Allen, Lee S. Schwartzberg, Robyn R. Young, Ahmed Y. Javed, Matthew P. Smeltzer, Furhan Yunus, Carmel S. Verrier, Mohammad Jahanzeb
Publikováno v:
Journal of Cancer and Allied Specialties, Vol 2, Iss 1 (2016)
Purpose: This phase II neoadjuvant study investigated whether nab paclitaxel, carboplatin and bevacizumab given before neoadjuvant doxorubicin/cyclophosphamide (AC) produced higher pathologic complete response (pCR) rates in triple- negative breast c
Externí odkaz:
https://doaj.org/article/167a5538fb324c858a09f1c7b1d521a1
In Vivo Delivery of a DNA-Encoded Monoclonal Antibody Protects Non-human Primates against Zika Virus
Autor:
Ghiabe Guibinga, Janess M. Mendoza, David B. Weiner, Laurent Humeau, Stephanie Ramos, Jian Yan, Sagar B. Kudchodkar, Trevor R.F. Smith, Kanika Asija, Jeffrey W. Allen, Piyush Borole, Jing Chen, Martina Beltramello, Ami Patel, Mamadou A. Bah, Karin Stettler, Davide Corti, Rianne Esquivel, Amy C. Durham, Hyeree Choi, Daniel H. Park, Shareef Shaheen, Kate E. Broderick, Karuppiah Muthumani
Publikováno v:
Molecular Therapy
Zika virus (ZIKV) infection is endemic to several world regions, and many others are at high risk for seasonal outbreaks. Synthetic DNA-encoded monoclonal antibody (DMAb) is an approach that enables in vivo delivery of highly potent mAbs to control i
Autor:
Mohammad G. Abdallah, Monica S. Allen, Jeffrey W. Allen, Joseph A. Buchanan-Vega, Robert Magnusson, Brett R. Wenner
Publikováno v:
Optical Sensors and Sensing Congress.
We determine the bulk index of a buffer and the surface index and thickness of an analyte. We use sensitivity data to calculate nominal variable changes and a lookup table for larger deviations.
Autor:
Jeffrey W. Allen, Joseph G. Grzywacz
Publikováno v:
Family Relations. 66:568-583
Family science has been doing translational science since before it came into vogue. Nevertheless, the field has been subjected to the same forces in the broader academy that have created a widening chasm between discovery and practice. Thus, the pri
Publikováno v:
Journal of Thoracic Oncology. 7:390-396
Background: Accurate staging of resected lung cancer requires mediastinal lymph node (MLN) examination. MLN dissection (MLND) and systematic sampling (SS) are acceptable procedures; random sampling (RS) and no sampling (NS) are not. Forty percent of
One of the most important challenges faced by the DoD is agility on a changing battlefield. Many times we are only a step ahead of foes, and solutions presented to the warfighter need to address these rapidly evolving threats. This demands agile and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e647d5f635244f91695012e4816da04a
https://doi.org/10.21236/ad1012979
https://doi.org/10.21236/ad1012979
Publikováno v:
Cancer. 117:134-142
BACKGROUND: Curative treatment of early stage nonsmall cell lung cancer (NSCLC) requires good quality surgical resection (GQR). The degree of compliance with national recommendations for GQR is poorly defined. We sought to quantitatively define the d
Autor:
Allen Berry, A. Farooq, David Spencer, Thomas F. O'Brien, Raymond U. Osarogiagbon, Jeffrey W. Allen
Publikováno v:
Journal of Thoracic Oncology. 5(2):191-196
PurposeMetastasis to lymph nodes (LNs) connotes poor prognosis in non-small cell lung cancer (NSCLC). Sufficient LNs must be examined to accurately determine LN negativity. Patients with no LNs examined (pNx) have an indeterminate stage, may have und
Autor:
Mohammad Jahanzeb, Jeffrey W. Allen
Publikováno v:
Journal of the National Comprehensive Cancer Network. 6:285-293
Non-small cell lung cancer (NSCLC) continues to be the leading cause of cancer-related mortality in the United States. Current standard care for treating NSCLC is surgical resection, when feasible, followed by adjuvant chemotherapy in stages II and I